The genomic 'inner fish' and a regulatory enigma in the vertebrates

doi:10.1186/jbiol131

Journal of Biology

Volume 8
Issue 3

Viewing options:

Abstract
Full text
PDF (244KB)

Associated material:

Related literature:

Articles citing this article
on BioMed Central
on Google Scholar
on PubMed Central
Other articles by authors
on Google Scholar

Malone J
Oliver B

on PubMed

Malone J
Oliver B
Related articles/pages
on Google

on Google Scholar

on PubMed

Tools:

Post to:

Minireview

The genomic 'inner fish' and a regulatory enigma in the vertebrates

John Malone and Brian Oliver

Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892, USA

author email corresponding author email

Journal of Biology 2009, 8:32doi:10.1186/jbiol131


Published:	16 April 2009

Abstract

Information on how genomic information from fish to human encodes the same tissues has until now emerged one gene at a time. The study published in this issue now provides lists of genes and their expression levels for 20 vertebrate tissues spanning 450 million years of vertebrate evolution. It reveals a core set of genes with similar tissue-expression patterns yet no common regulatory signatures – a gene-expression paradox.