Conservation of core gene expression in vertebrate tissues
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* Corresponding authors: Quaid D Morris quaid.morris@gmail.com - Timothy R Hughes t.hughes@utoronto.ca
Journal of Biology 2009, 8:33 doi:10.1186/jbiol130
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BioMed Central: 8 citations
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Research article
Lino Ometto, Mingai Li, Luisa Bresadola, Claudio Varotto BMC Evolutionary Biology 2012, 12:7 (18 January 2012) |
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Review
Microarrays, deep sequencing and the true measure of the transcriptome John H Malone, Brian Oliver BMC Biology 2011, 9:34 (31 May 2011) Global measures of gene expression can now be extracted either from microarrays or from RNA-seq, which do not always seem to give the same answer. Malone and Oliver review the advantages and limitations of each and conclude that, with some important exceptions, they tell the same story.
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Research highlight
The similarity of gene expression between human and mouse tissues Robin D Dowell Genome Biology 2011, 12:101 (17 January 2011) Meta-analysis of human and mouse microarray data reveals conservation of patterns of gene expression.
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Research
Selection for the compactness of highly expressed genes in Gallus gallus You S Rao, Zhang F Wang, Xue W Chai, Guo Z Wu, Ming Zhou, Qing H Nie, Xi Q Zhang Biology Direct 2010, 5:35 (14 May 2010) |
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Editorial
Top ten in Journal of Biology in 2009: stem cells, influenza, pit bulls, Darwin, and more Miranda Robertson Journal of Biology 2009, 8:102 (31 December 2009) |
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Editorial
Gene regulation, evolvability and the limits of genomics Miranda Robertson Journal of Biology 2009, 8:94 (24 December 2009) |
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Opinion
Promoter architecture and the evolvability of gene expression Itay Tirosh, Naama Barkai, Kevin J Verstrepen Journal of Biology 2009, 8:95 (14 December 2009) Major evolutionary change depends on changes in gene expression. Itay Tirosh and colleagues review recent research on the influence of promoter architecture and mutations in regulatory proteins on divergent expression patterns and suggest what is required for evolvability.
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Minireview
The genomic 'inner fish' and a regulatory enigma in the vertebrates John Malone, Brian Oliver Journal of Biology 2009, 8:32 (16 April 2009) Brian Oliver and John Malone invoke our 'inner fish' in their commentary on new research in Journal of Biology which shows high conservation of tissue-specific gene expression from fish to human but without corresponding conservation in the gene regulatory sequences.
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