Resolution:
## Figure 2.
Population replacement and population suppression.
(a) In population replacement strategies, the wild population is invaded by a heritable
modification (e.g. transgene [5,9] or pathogenic Wolbachia [8]) that reduces the vector competence of the mosquitoes that carry it. The number of
competent vectors therefore declines, but the total number of (female) mosquitoes
remains relatively constant, though possibly with some transient change during the
invasion. (b) In contrast, a population suppression strategy aims to reduce the total number of
vector mosquitoes. The two panels illustrate the changes in female population number
and type over time for the two strategies. In both cases the situation will eventually
reverse due to various pressures such as resistance, mutation, immigration, etc, unless
some maintenance activities are undertaken.
Alphey |