Letting go: modification of cell adhesion during apoptosis

doi:10.1186/jbiol152

Journal of Biology

Volume 8
Issue 5

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Letting go: modification of cell adhesion during apoptosis

Magali Suzanne¹^,2 and Hermann Steller¹

¹The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA

²Institute of Developmental Biology and Cancer, CNRS UMR6543, UniversitéNice – Sophia Antipolis, Parc Valrose, 06108 Nice cedex 2, France

author email corresponding author email

Journal of Biology 2009, 8:49doi:10.1186/jbiol152


Published:	28 May 2009

Abstract

Apoptosis appears to be a carefully orchestrated process for the ordered dismantling of cells. A recent paper in BMC Developmental Biology shows that the disassembly of adherens junctions during apoptosis in Drosophila is progressive and requires the amino-terminal cleavage of the β-catenin Armadillo by the apoptotic effector caspase DrICE.