Letting go: modification of cell adhesion during apoptosis
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Journal of Biology 2009, 8:49 doi:10.1186/jbiol152Published: 28 May 2009
Apoptosis appears to be a carefully orchestrated process for the ordered dismantling of cells. A recent paper in BMC Developmental Biology shows that the disassembly of adherens junctions during apoptosis in Drosophila is progressive and requires the amino-terminal cleavage of the β-catenin Armadillo by the apoptotic effector caspase DrICE.