Journal of Biology
Tools
Share this article

Email updates

Keep up to date with the latest news and articles from Journal of Biology and BioMed Central.

Minireview

Physical forces in myelination and repair: a question of balance?

Nina G Bauer* and Charles ffrench-Constant

Author Affiliations

MRC Centre for Regenerative Medicine, Centre for Multiple Sclerosis Research, The University of Edinburgh, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

For all author emails, please log on.

Journal of Biology 2009, 8:78 doi:10.1186/jbiol169

Published: 25 September 2009

Abstract

A recent report in BMC Cell Biology examines how the balance of extracellular forces and intracellular contractions regulate the shape changes required for oligodendrocyte myelination. A failure of remyelination such as seen in multiple sclerosis could be caused by loss of this balance.

See related research article http://www.biomedcentral.com/1471-2121/10/71 webcite