Physical forces in myelination and repair: a question of balance?
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* Corresponding author: Nina G Bauer nina.g.bauer@ed.ac.uk
MRC Centre for Regenerative Medicine, Centre for Multiple Sclerosis Research, The University of Edinburgh, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
Journal of Biology 2009, 8:78 doi:10.1186/jbiol169
Published: 25 September 2009Abstract
A recent report in BMC Cell Biology examines how the balance of extracellular forces and intracellular contractions regulate the shape changes required for oligodendrocyte myelination. A failure of remyelination such as seen in multiple sclerosis could be caused by loss of this balance.
See related research article http://www.biomedcentral.com/1471-2121/10/71 webcite