Physical forces in myelination and repair: a question of balance?

doi:10.1186/jbiol169

Journal of Biology

Volume 8
Issue 8

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Physical forces in myelination and repair: a question of balance?

Nina G Bauer and Charles ffrench-Constant

MRC Centre for Regenerative Medicine, Centre for Multiple Sclerosis Research, The University of Edinburgh, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

author email corresponding author email

Journal of Biology 2009, 8:78doi:10.1186/jbiol169


Published:	25 September 2009

Abstract

A recent report in BMC Cell Biology examines how the balance of extracellular forces and intracellular contractions regulate the shape changes required for oligodendrocyte myelination. A failure of remyelination such as seen in multiple sclerosis could be caused by loss of this balance.

See related research article http://www.biomedcentral.com/1471-2121/10/71 webcite