Physical forces in myelination and repair: a question of balance?
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Journal of Biology 2009, 8:78 doi:10.1186/jbiol169Published: 25 September 2009
A recent report in BMC Cell Biology examines how the balance of extracellular forces and intracellular contractions regulate the shape changes required for oligodendrocyte myelination. A failure of remyelination such as seen in multiple sclerosis could be caused by loss of this balance.