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Volume 8 (2009) - August 2009

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Minireview   Free Highly Accessed

The absolute pitch mind continues to reveal itself

Patrick Bermudez, Robert J Zatorre Journal of Biology 2009, 8:75 (27 August 2009)

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Insulators as mediators of intra- and inter-chromosomal interactions: a common evolutionary theme

Chin-Tong Ong, Victor G Corces Journal of Biology 2009, 8:73 (27 August 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Ong and Corces review the long-range inter- and intrachromosomal interactions that regulate gene expression in eukaryotes and discuss a recent study in BMC Molecular Biology that helps illustrate the diversity of insulation mechanisms at the interaction points.

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The complex genetic basis of simple behavior

Anna J Jasinska, Nelson B Freimer Journal of Biology 2009, 8:71 (27 August 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Jasinska and Freimer discuss a recent paper in BMC Biology by Mackay and colleagues that reveals the complex genetics behind fruitfly aggression, with implications for the dissection of human behaviours

Editorial   Open Access

Dysregulating the regulators

Miranda Robertson Journal of Biology 2009, 8:60 (27 August 2009)

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Beyond toxicity: aryl hydrocarbon receptor-mediated functions in the immune system

Brigitta Stockinger Journal of Biology 2009, 8:61 (17 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Brigitta Stockinger argues that the immunosuppressive effects of dioxin and other toxic aryl hydrocarbons may reflect disruption of the regulatory interactions between immune cells, which variably express the specific receptor for these compounds.

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Infectious causes of cancer and their detection

Lucy Dalton-Griffin, Paul Kellam Journal of Biology 2009, 8:67 (11 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Lucy Dalton-Griffin and Paul Kellam discuss the role of viruses in cancer following a recent paper in BMC Medical Genomics describing a new method of detecting viral DNA in cancer cells.

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The human spermatozoon – a stripped down but refined machine

Christopher LR Barratt, Vanessa Kay, Senga K Oxenham Journal of Biology 2009, 8:63 (7 August 2009)

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Christopher Barratt and colleagues review our current knowledge of the human sperm cell and available treatments for male subfertility in the light of a recent paper in BMC Developmental Biology on the role of the annulus.

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Parasite immunomodulation and polymorphisms of the immune system

Rick M Maizels Journal of Biology 2009, 8:62 (5 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Rick Maizels discusses a recent paper in BMC Biology on wild mammals that lend support to the hygiene hypothesis, and explains why genetic variants that reduce parasite-induced immunosuppression are associated with an increase in allergic reactions.


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