Articles
Volume 8 (2009) - March 2009
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Distant metastasis: not out of reach any more François Bertucci, Daniel Birnbaum Journal of Biology 2009, 8:28 (27 March 2009) Bertucci and Birnbaum review gene expression profiles published in BMC Medicine and BMC Cancer on distant cancer metastasis that predict poor outcome, but may help target anti-angiogenesis therapies.
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Pitfalls in the phylogenomic evaluation of human disease-causing mutations Andrew OM Wilkie Journal of Biology 2009, 8:26 (24 March 2009) Andrew Wilkie discusses (the pitfalls of) a new phylogenomic study, published in BMC Evolutionary Biology, that has identified conserved sequences in the MSX homeobox family proteins suspected to be involved in human diseases.
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Liaison amid disorder: non-native interactions may underpin long-range coupling in proteins Hue Chan, Zhuqing Zhang Journal of Biology 2009, 8:27 (13 March 2009) Chan and Zhang, discussing a study published in BMC Structural Biology, argue that while close contacts between amino acids stabilize protein folds, long-range destablilizing interactions may be important in allowing them to evolve new functions.
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Comment
Are we training pit bulls to review our manuscripts? Virginia Walbot Journal of Biology 2009, 8:24 (9 March 2009) Virginia Walbot accepts some of the blame for remorselessly negative reviewers, and suggests a training program for graduate students and post docs that will deliver a fairer assessment of manuscripts.
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Ingo Braasch, Walter Salzburger Journal of Biology 2009, 8:25 (5 March 2009) Ingo Braasch and Walter Salzburger discuss an article published in BMC Evolutionary Biology that suggests how differential evolution of the duplicated vitellogenin yolk protein genes in fish allowed the development of crucial new spawning strategies.
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