Articles
Volume 8 (2009) - October 2009
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Review
Mechanisms of ubiquitin transfer by the anaphase-promoting complex Mary E Matyskiela, Monica C Rodrigo-Brenni, David O Morgan Journal of Biology 2009, 8:92 (26 October 2009) The anaphase-promoting complex (APC) is a giant ubiquitin ligase required for separation of the chromosomes at metaphase and exit from mitosis. David Morgan and colleagues explain how this complex combines specificity with flexibility, with implications for regulation by ubiquitination in general.
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Minireview
Targeting TNF-α for cancer therapy Elizabeth R Burton, Steven K Libutti Journal of Biology 2009, 8:85 (23 October 2009) |
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Minireview
TEs or not TEs? That is the evolutionary question Keren Vaknin, Amir Goren, Gil Ast Journal of Biology 2009, 8:83 (23 October 2009) |
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Opinion
Molecular machines or pleiomorphic ensembles: signaling complexes revisited Bruce J Mayer, Michael L Blinov, Leslie M Loew Journal of Biology 2009, 8:81 (16 October 2009) Intracellular signaling complexes are not machines but form and dissolve in myriad combinations. Bruce Mayer argues in a new series called Ockham's broom that it is time to confront this reality with modern imaging and mathematical tools.
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Editorial
Miranda Robertson Journal of Biology 2009, 8:79 (16 October 2009) |
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Minireview
Decoding the multifaceted HIV-1 virus-host interactome Eric Y Chan, Marcus J Korth, Michael G Katze Journal of Biology 2009, 8:84 (13 October 2009) |
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Minireview
Michael L Arnold, Noland H Martin Journal of Biology 2009, 8:82 (13 October 2009) |
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Question & Answer
Q&A: What are pharmacological chaperones and why are they interesting? Dagmar Ringe, Gregory A Petsko Journal of Biology 2009, 8:80 (13 October 2009) Small molecules that stabilize mutant proteins with high specificity can be used to treat protein misfolding and metabolic diseases: in a Q&A highlighting recent successes, Dagmar Ringe and Gregory Petsko explain how.
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Minireview
The effects of lipids on channel function Anthony G Lee Journal of Biology 2009, 8:86 (6 October 2009) |
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Editorial
Open questions about influenza A (H1N1) 2009 Miranda Robertson Journal of Biology 2009, 8:68 (2 October 2009) |
