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Regulation of metabolism in Caenorhabditis elegans longevity
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* Corresponding author: Donald L Riddle driddle@msl.ubc.ca
1 Department of Medical Genetics, Faculty of Medicine, 263-2185 East Mall, The University of British Columbia, Vancouver, BC, V6T 1Z4 Canada
2 Michael Smith Laboratories, The University of British Columbia, Vancouver, BC, V6T 1Z4 Canada
Journal of Biology 2010, 9:7 doi:10.1186/jbiol215
Published: 10 February 2010Abstract
The nematode Caenorhabditis elegans is a favorite model for the study of aging. A wealth of genetic and genomic studies show that metabolic regulation is a hallmark of life-span modulation. A recent study in BMC Biology identifying metabolic signatures for longevity suggests that amino-acid pools may be important in longevity.
See research article http://www.biomedcentral.com/1741-7007/8/14 webcite.