Regulation of metabolism in Caenorhabditis elegans longevity
1 Department of Medical Genetics, Faculty of Medicine, 263-2185 East Mall, The University of British Columbia, Vancouver, BC, V6T 1Z4 Canada
2 Michael Smith Laboratories, The University of British Columbia, Vancouver, BC, V6T 1Z4 Canada
Journal of Biology 2010, 9:7 doi:10.1186/jbiol215Published: 10 February 2010
The nematode Caenorhabditis elegans is a favorite model for the study of aging. A wealth of genetic and genomic studies show that metabolic regulation is a hallmark of life-span modulation. A recent study in BMC Biology identifying metabolic signatures for longevity suggests that amino-acid pools may be important in longevity.