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Regulation of metabolism in Caenorhabditis elegans longevity

Marco Gallo1 and Donald L Riddle12*

Author affiliations

1 Department of Medical Genetics, Faculty of Medicine, 263-2185 East Mall, The University of British Columbia, Vancouver, BC, V6T 1Z4 Canada

2 Michael Smith Laboratories, The University of British Columbia, Vancouver, BC, V6T 1Z4 Canada

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Citation and License

Journal of Biology 2010, 9:7  doi:10.1186/jbiol215

Published: 10 February 2010

Abstract

The nematode Caenorhabditis elegans is a favorite model for the study of aging. A wealth of genetic and genomic studies show that metabolic regulation is a hallmark of life-span modulation. A recent study in BMC Biology identifying metabolic signatures for longevity suggests that amino-acid pools may be important in longevity.

See research article http://www.biomedcentral.com/1741-7007/8/14 webcite.