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Open Access Research article

Madm (Mlf1 adapter molecule) cooperates with Bunched A to promote growth in Drosophila

Silvia Gluderer1, Erich Brunner2, Markus Germann3, Virginija Jovaisaite1, Changqing Li45, Cyrill A Rentsch36, Ernst Hafen1 and Hugo Stocker1*

Author Affiliations

1 Institute of Molecular Systems Biology, ETH Zurich, Wolfgang-Pauli-Strasse 16, 8093 Zurich, Switzerland

2 Center for Model Organism Proteomes, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland

3 Urology Research Laboratory, Departments of Urology and Clinical Research, University of Bern, Murtenstrasse 35, 3010 Bern, Switzerland

4 Institute of Zoology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland

5 Current address: Department of Medicine, Epigenetics and Progenitor Cell Keystone Program, Fox Chase Cancer Center, Cottman Avenue 333, Philadelphia, PA 19111, USA

6 Current address: Urologische Universitätsklinik, Universitätsspital Basel, Spitalstrasse 21, 4031 Basel, Switzerland

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Journal of Biology 2010, 9:9  doi:10.1186/jbiol216

Published: 11 February 2010

Additional files

Additional file 1:

Candidate list of three AP-MS experiments, including supporting information.

Format: PDF Size: 75KB Download file

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Open Data

Additional file 2:

Mapping of the BunA region sufficient for the interaction with Madm by means of Y2H and co-IP experiments.

Format: PDF Size: 1.9MB Download file

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Open Data

Additional file 3:

Mapping of the Madm region sufficient for the interaction with BunA by means of Y2H and co-IP experiments.

Format: PDF Size: 1.5MB Download file

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Open Data

Additional file 4:

Alignments of BunA and Madm interaction regions and western blots showing the specificity of the anti-BunA antibody.

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Open Data

Additional file 5:

Pictures of wing notches in bunA hypomorphic flies and Madm, bunA double-mutant mosaic eyes.

Format: PDF Size: 4.5MB Download file

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Open Data