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Volume 9 (2010) - January 2010

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The THO complex as a key mRNP biogenesis factor in development and cell differentiation

Sonia Jimeno, Andrés Aguilera Journal of Biology 2010, 9:6 (28 January 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The THO complex is implicated in RNA export from the nucleus, but exactly how is not clear. Jimeno and Aguilera discuss a new report on the THOC5 subunit in BMC Biology that suggests a role in differentiation.

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SnoPatrol: how many snoRNA genes are there?

Paul P Gardner, Alex Bateman, Anthony M Poole Journal of Biology 2010, 9:4 (25 January 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Gardner, Bateman and Poole review the current knowledge of small nucleolar RNAs (snoRNAs) and discuss two BMC Genomic papers reporting the identification of novel snoRNAs and the likelihood that there are many more out there.

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Sometimes one just isn't enough: do vertebrates contain an H2A.Z hyper-variant?

Monika Mehta, Hyun-Soo Kim, Michael-Christopher Keogh Journal of Biology 2010, 9:3 (21 January 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Nucleosomes present a variable platform for recruitment of transcriptional and repair machineries because of variant histones and post-translational modifications. Keogh and colleagues discuss reports in BMC Biology and BMC Evolutionary Biology that suggest further complexity, in conserved variants of the variants.

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Apical polarity in three-dimensional culture systems: where to now?

Jamie L Inman, Mina J Bissell Journal of Biology 2010, 9:2 (21 January 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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The water flea Daphnia - a 'new' model system for ecology and evolution?

Angelika Stollewerk Journal of Biology 2010, 9:21 (13 January 2010)

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