GO category Median vs T Pearson WMW p-value Median vs T Pearson WMW Z-score synapse [GO:0045202] 1.53E-08 5.65815 system process [GO:0003008] 2.18E-06 4.735887 multicellular organismal process [GO:0032501] 4.73E-06 4.576541 plasma membrane [GO:0005886] 1.17E-05 4.382318 system development [GO:0048731] 3.21E-05 4.158321 plasma membrane part [GO:0044459] 3.47E-05 4.140321 muscle development [GO:0007517] 4.98E-05 4.056684 synapse part [GO:0044456] 0.000152708 3.786624 neuron projection [GO:0043005] 0.000154116 3.784341 synaptic transmission [GO:0007268] 0.000155252 3.782515 postsynaptic membrane [GO:0045211] 0.000209452 3.707334 calcium ion binding [GO:0005509] 0.00021477 3.700978 neurological system process [GO:0050877] 0.000228675 3.685031 anatomical structure development [GO:0048856] 0.000456689 3.504952 structural constituent of muscle [GO:0008307] 0.000491997 3.485076 contractile fiber part [GO:0044449] 0.0005347 3.462742 G-protein coupled receptor protein signaling pathway [GO:0007186] 0.000668048 3.402367 transmission of nerve impulse [GO:0019226] 0.000807862 3.350087 neuron development [GO:0048666] 0.00083365 3.341373 structural constituent of eye lens [GO:0005212] 0.000852674 3.335104 neurogenesis [GO:0022008] 0.001317112 3.212225 extracellular region part [GO:0044421] 0.001363938 3.202176 neuron differentiation [GO:0030182] 0.001412673 3.192049 myofibril [GO:0030016] 0.001417635 3.191036 contractile fiber [GO:0043292] 0.001417635 3.191036 striated muscle development [GO:0014706] 0.001479103 3.178753 generation of precursor metabolites and energy [GO:0006091] 0.001510299 3.172697 regulation of immune system process [GO:0002682] 0.001571058 3.161227 axon [GO:0030424] 0.001573667 3.160744 nervous system development [GO:0007399] 0.001678658 3.141882 solute:sodium symporter activity [GO:0015370] 0.002016416 3.087804 anion:cation symporter activity [GO:0015296] 0.002100585 3.07563 cell junction [GO:0030054] 0.002188576 3.063372 wound healing [GO:0042060] 0.002241093 3.05627 cell-cell signaling [GO:0007267] 0.002247162 3.055459 extracellular space [GO:0005615] 0.002256174 3.054259 hemostasis [GO:0007599] 0.002276332 3.051589 visual perception [GO:0007601] 0.002358766 3.040894 sensory perception of light stimulus [GO:0050953] 0.002358766 3.040894 generation of neurons [GO:0048699] 0.00237639 3.038652 ribosome biogenesis and assembly [GO:0042254] 0.00258499 3.013211 skeletal muscle development [GO:0007519] 0.002625129 3.008532 organ development [GO:0048513] 0.002690848 3.001011 extracellular region [GO:0005576] 0.002702964 2.999643 channel activity [GO:0015267] 0.002814141 2.987343 passive transmembrane transporter activity [GO:0022803] 0.002814141 2.987343 sarcomere [GO:0030017] 0.002935645 2.974398 integral to plasma membrane [GO:0005887] 0.002967605 2.971074 intrinsic to plasma membrane [GO:0031226] 0.002967605 2.971074 organic acid:sodium symporter activity [GO:0005343] 0.00302371 2.965317 multicellular organismal development [GO:0007275] 0.003145377 2.953161 muscle system process [GO:0003012] 0.003190167 2.948794 pore complex [GO:0046930] 0.003453247 2.924216 calcium channel activity [GO:0005262] 0.003518347 2.918398 intracellular protein transport across a membrane [GO:0065002] 0.00376036 2.897595 axonogenesis [GO:0007409] 0.003794484 2.89476 neuron morphogenesis during differentiation [GO:0048667] 0.003794484 2.89476 neurite morphogenesis [GO:0048812] 0.003794484 2.89476 neurite development [GO:0031175] 0.004333837 2.852782 sensory perception [GO:0007600] 0.004393686 2.84842 regulation of body fluid levels [GO:0050878] 0.0045068 2.840322 transcriptional repressor complex [GO:0017053] 0.004587508 2.834656 blood coagulation [GO:0007596] 0.004982177 2.808184 startle response [GO:0001964] 0.005196913 2.794568 cell surface receptor linked signal transduction [GO:0007166] 0.005270519 2.790018 dendrite [GO:0030425] 0.005272651 2.789887 positive regulation of immune system process [GO:0002684] 0.005282659 2.789273 aromatic amino acid family metabolic process [GO:0009072] 0.005462637 2.778406 behavior [GO:0007610] 0.005522956 2.774836 response to organic substance [GO:0010033] 0.00565844 2.766944 sodium:dicarboxylate symporter activity [GO:0017153] 0.005740566 2.762243 muscle contraction [GO:0006936] 0.006051677 2.744968 coagulation [GO:0050817] 0.00658278 2.717245 regulation of hormone secretion [GO:0046883] 0.00700379 2.696664 wide pore channel activity [GO:0022829] 0.007303502 2.682679 aromatic compound catabolic process [GO:0019439] 0.007317491 2.682039 humoral immune response mediated by circulating immunoglobulin [GO:0002455] 0.007405817 2.678023 activation of plasma proteins during acute inflammatory response [GO:0002541] 0.007405817 2.678023 complement activation [GO:0006956] 0.007405817 2.678023 complement activation, classical pathway [GO:0006958] 0.007405817 2.678023 negative regulation of immune system process [GO:0002683] 0.007424908 2.67716 cellular homeostasis [GO:0019725] 0.007596372 2.669502 homeostatic process [GO:0042592] 0.007649562 2.667158 regulation of adenylate cyclase activity [GO:0045761] 0.008521945 2.630659 secretory granule [GO:0030141] 0.008882204 2.616555 neurotransmitter transport [GO:0006836] 0.009038004 2.610613 voltage-gated calcium channel complex [GO:0005891] 0.00908068 2.609002 cation transmembrane transporter activity [GO:0008324] 0.009305807 2.60061 regulation of G-protein coupled receptor protein signaling pathway [GO:0008277] 0.009644338 2.588327 humoral immune response [GO:0006959] 0.010440409 2.560891 mRNA transport [GO:0051028] 0.010492851 2.55915 cell fate commitment [GO:0045165] 0.010597779 2.555689 vitamin binding [GO:0019842] 0.010806694 2.548888 neurotransmitter binding [GO:0042165] 0.010914299 2.545431 regulation of ion transport [GO:0043269] 0.011155042 2.537804 exopeptidase activity [GO:0008238] 0.011196443 2.536507 cellular morphogenesis during differentiation [GO:0000904] 0.011548574 2.525646 endopeptidase inhibitor activity [GO:0004866] 0.011597706 2.524154 protease inhibitor activity [GO:0030414] 0.011597706 2.524154 circulatory system process [GO:0003013] 0.011764384 2.519134 blood circulation [GO:0008015] 0.011764384 2.519134 cytoskeleton [GO:0005856] 0.012052772 2.510595 regulation of immune response [GO:0050776] 0.012078755 2.509835 energy derivation by oxidation of organic compounds [GO:0015980] 0.012361117 2.501664 calmodulin-dependent protein kinase activity [GO:0004683] 0.012375456 2.501254 regulation of secretion [GO:0051046] 0.012532494 2.496785 sequestering of calcium ion [GO:0051208] 0.012995446 2.483894 sequestering of metal ion [GO:0051238] 0.012995446 2.483894 synapse organization and biogenesis [GO:0050808] 0.014159206 2.453199 regulation of peptide secretion [GO:0002791] 0.015975672 2.409471 rhodopsin-like receptor activity [GO:0001584] 0.016057072 2.407616 voltage-gated calcium channel activity [GO:0005245] 0.016116884 2.406258 anion transmembrane transporter activity [GO:0008509] 0.016282543 2.40252 cyclase activity [GO:0009975] 0.016402602 2.399832 glycolipid metabolic process [GO:0006664] 0.016509349 2.397456 Z disc [GO:0030018] 0.016714477 2.392929 I band [GO:0031674] 0.016714477 2.392929 response to external stimulus [GO:0009605] 0.016848552 2.389996 neuropeptide signaling pathway [GO:0007218] 0.017644433 2.372996 regulation of blood pressure [GO:0008217] 0.017954637 2.366552 vasodilation [GO:0042311] 0.01857027 2.354047 regulation of neurotransmitter levels [GO:0001505] 0.019275829 2.340153 insulin secretion [GO:0030073] 0.019302786 2.339631 regulation of insulin secretion [GO:0050796] 0.019302786 2.339631 response to wounding [GO:0009611] 0.019552844 2.33482 innate immune response [GO:0045087] 0.01973374 2.331372 transmembrane receptor activity [GO:0004888] 0.020032671 2.325735 regulation of biological quality [GO:0065008] 0.02059994 2.315237 developmental process [GO:0032502] 0.020733307 2.312806 porin activity [GO:0015288] 0.020946537 2.308947 regulation of muscle contraction [GO:0006937] 0.021173739 2.304872 digestion [GO:0007586] 0.021176587 2.304821 serine-type endopeptidase inhibitor activity [GO:0004867] 0.021654819 2.296369 cell migration [GO:0016477] 0.02222133 2.286563 regulation of multicellular organismal process [GO:0051239] 0.022519533 2.281489 cAMP-mediated signaling [GO:0019933] 0.022795042 2.276852 membrane-bounded vesicle [GO:0031988] 0.02340705 2.266725 patterning of blood vessels [GO:0001569] 0.023641171 2.262911 energy reserve metabolic process [GO:0006112] 0.025422992 2.234914 second-messenger-mediated signaling [GO:0019932] 0.025439 2.23467 enzyme inhibitor activity [GO:0004857] 0.025515736 2.233504 sequence-specific DNA binding [GO:0043565] 0.026185254 2.223453 neurotransmitter receptor activity [GO:0030594] 0.026205453 2.223153 visual learning [GO:0008542] 0.027123566 2.209735 aromatic compound metabolic process [GO:0006725] 0.027499438 2.204354 positive regulation of immune response [GO:0050778] 0.028111107 2.195732 negative regulation of cell motility [GO:0051271] 0.028267019 2.193561 amine receptor activity [GO:0008227] 0.028834799 2.185738 di-, tri-valent inorganic cation transport [GO:0015674] 0.028862676 2.185357 catecholamine metabolic process [GO:0006584] 0.028870609 2.185249 phenol metabolic process [GO:0018958] 0.028870609 2.185249 dopamine metabolic process [GO:0042417] 0.028870609 2.185249 regulation of cell-cell adhesion [GO:0022407] 0.028879773 2.185124 calcium ion transport [GO:0006816] 0.028893134 2.184942 carbon-sulfur lyase activity [GO:0016846] 0.029094829 2.182199 axon guidance [GO:0007411] 0.029184809 2.180981 amine binding [GO:0043176] 0.029668171 2.174492 response to light stimulus [GO:0009416] 0.029695571 2.174127 negative regulation of response to stimulus [GO:0048585] 0.029900388 2.171407 electron transport chain [GO:0022900] 0.030457572 2.164088 monocarboxylic acid metabolic process [GO:0032787] 0.031045895 2.156484 microtubule organizing center [GO:0005815] 0.031788659 2.147058 non-membrane-bounded organelle [GO:0043228] 0.031901273 2.145645 intracellular non-membrane-bounded organelle [GO:0043232] 0.031901273 2.145645 caveola [GO:0005901] 0.032113828 2.142991 melanosome [GO:0042470] 0.032238063 2.141446 pigment granule [GO:0048770] 0.032238063 2.141446 activation of adenylate cyclase activity [GO:0007190] 0.032868193 2.13369 positive regulation of cyclase activity [GO:0031281] 0.032868193 2.13369 positive regulation of adenylate cyclase activity [GO:0045762] 0.032868193 2.13369 positive regulation of lyase activity [GO:0051349] 0.032868193 2.13369 platelet activation [GO:0030168] 0.033424586 2.126946 heart morphogenesis [GO:0003007] 0.033511686 2.125899 positive regulation of T cell differentiation [GO:0045582] 0.034275001 2.116821 positive regulation of lymphocyte differentiation [GO:0045621] 0.034275001 2.116821 spindle organization and biogenesis [GO:0007051] 0.034893491 2.109592 external side of plasma membrane [GO:0009897] 0.035478834 2.102851 detection of visible light [GO:0009584] 0.035930261 2.097716 detection of light stimulus involved in visual perception [GO:0050908] 0.035930261 2.097716 detection of light stimulus involved in sensory perception [GO:0050962] 0.035930261 2.097716 membrane-enclosed lumen [GO:0031974] 0.036433522 2.092056 organelle lumen [GO:0043233] 0.036433522 2.092056 glycosphingolipid metabolic process [GO:0006687] 0.037709551 2.077998 cell projection [GO:0042995] 0.037824637 2.07675 nuclear pore [GO:0005643] 0.038106246 2.07371 growth cone [GO:0030426] 0.038316005 2.071458 ion channel activity [GO:0005216] 0.038755583 2.066773 epithelial to mesenchymal transition [GO:0001837] 0.0390614 2.063539 delamination [GO:0060232] 0.0390614 2.063539 cell development [GO:0048468] 0.039741874 2.056422 regulation of response to stimulus [GO:0048583] 0.040224365 2.051437 transmembrane transporter activity [GO:0022857] 0.04027441 2.050923 synaptic vesicle [GO:0008021] 0.040432459 2.049303 translational elongation [GO:0006414] 0.040461202 2.049009 synaptogenesis [GO:0007416] 0.040521027 2.048398 presynaptic membrane [GO:0042734] 0.040607635 2.047514 electron transporter activity [GO:0005489] 0.041122953 2.042288 learning [GO:0007612] 0.041596731 2.037532 substrate specific channel activity [GO:0022838] 0.041677295 2.036728 rRNA processing [GO:0006364] 0.041772196 2.035783 rRNA metabolic process [GO:0016072] 0.041772196 2.035783 positive regulation of response to stimulus [GO:0048584] 0.042343835 2.030125 heparin binding [GO:0008201] 0.042505908 2.028533 regulation of lipid metabolic process [GO:0019216] 0.042665367 2.026971 phosphatase regulator activity [GO:0019208] 0.042845985 2.025208 cytoplasmic membrane-bounded vesicle [GO:0016023] 0.043287132 2.020929 cytokine binding [GO:0019955] 0.043421916 2.019629 aerobic respiration [GO:0009060] 0.043740428 2.01657 cell activation [GO:0001775] 0.043805406 2.015948 carboxylesterase activity [GO:0004091] 0.044015384 2.013944 solute:cation symporter activity [GO:0015294] 0.044040342 2.013707 locomotory behavior [GO:0007626] 0.044263198 2.01159 receptor activity [GO:0004872] 0.044967674 2.004957 regulation of localization [GO:0032879] 0.045249839 2.002325 regulation of transport [GO:0051049] 0.045249839 2.002325 detection of light stimulus [GO:0009583] 0.046212779 1.993445 ion transmembrane transporter activity [GO:0015075] 0.046246786 1.993134 embryonic organ development [GO:0048568] 0.046357503 1.992124 cell redox homeostasis [GO:0045454] 0.046977129 1.986506 cyclic nucleotide biosynthetic process [GO:0009190] 0.047193188 1.984562 intermediate filament [GO:0005882] 0.0473649 1.983023 intermediate filament cytoskeleton [GO:0045111] 0.0473649 1.983023 G-protein coupled receptor activity [GO:0004930] 0.047469888 1.982084 regulation of vasodilation [GO:0042312] 0.048428736 1.973587 immunoglobulin mediated immune response [GO:0016064] 0.048627569 1.971843 B cell mediated immunity [GO:0019724] 0.048627569 1.971843 pattern binding [GO:0001871] 0.049061113 1.96806 glycosaminoglycan binding [GO:0005539] 0.049061113 1.96806 polysaccharide binding [GO:0030247] 0.049061113 1.96806 cellular lipid catabolic process [GO:0044242] 0.049198123 1.966871 glycerol ether metabolic process [GO:0006662] 0.049699228 1.962544 phosphoinositide-mediated signaling [GO:0048015] 0.049940758 1.960471 cyclic-nucleotide-mediated signaling [GO:0019935] 0.051094119 1.950688 receptor signaling protein activity [GO:0005057] 0.051757909 1.945142 chromosomal part [GO:0044427] 0.052237644 1.94117 lipid metabolic process [GO:0006629] 0.05229111 1.940729 cellular respiration [GO:0045333] 0.052573212 1.93841 chromosome, pericentric region [GO:0000775] 0.052628614 1.937956 oligosaccharyl transferase activity [GO:0004576] 0.053213864 1.933181 dolichyl-diphosphooligosaccharide-protein glycotransferase activity [GO:0004579] 0.053213864 1.933181 oligosaccharyl transferase complex [GO:0008250] 0.053213864 1.933181 peptidyl-asparagine modification [GO:0018196] 0.053213864 1.933181 protein amino acid N-linked glycosylation via asparagine [GO:0018279] 0.053213864 1.933181 protein serine/threonine kinase activity [GO:0004674] 0.053260636 1.932802 dystrophin-associated glycoprotein complex [GO:0016010] 0.053731964 1.928991 fatty acid beta-oxidation [GO:0006635] 0.054254269 1.924801 neurotransmitter metabolic process [GO:0042133] 0.05445372 1.92321 heart process [GO:0003015] 0.055310846 1.916426 heart contraction [GO:0060047] 0.055310846 1.916426 mismatch repair complex binding [GO:0032404] 0.058030232 1.895469 mesenchymal cell development [GO:0014031] 0.058973106 1.888394 mesenchymal cell differentiation [GO:0048762] 0.058973106 1.888394 signal transducer activity [GO:0004871] 0.059674238 1.883193 molecular transducer activity [GO:0060089] 0.059674238 1.883193 peptide metabolic process [GO:0006518] 0.06047881 1.877287 regulation of cyclase activity [GO:0031279] 0.060730393 1.875453 regulation of lyase activity [GO:0051339] 0.060730393 1.875453 cell communication [GO:0007154] 0.060788023 1.875034 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [GO:0016796] 0.061292615 1.871379 centrosome [GO:0005813] 0.062042446 1.865992 phototransduction [GO:0007602] 0.062304576 1.864122 phosphorus metabolic process [GO:0006793] 0.063025283 1.859013 phosphate metabolic process [GO:0006796] 0.063025283 1.859013 phosphorus-oxygen lyase activity [GO:0016849] 0.063203441 1.857758 lipid homeostasis [GO:0055088] 0.063624293 1.854803 cotranslational protein targeting to membrane [GO:0006613] 0.063913894 1.85278 gliogenesis [GO:0042063] 0.064917511 1.845826 cyclic nucleotide metabolic process [GO:0009187] 0.06554942 1.841492 acetyltransferase activity [GO:0016407] 0.065860875 1.839369 metal ion transport [GO:0030001] 0.06610004 1.837745 sensory perception of chemical stimulus [GO:0007606] 0.0663269 1.836208 sensory perception of smell [GO:0007608] 0.0663269 1.836208 G-protein coupled photoreceptor activity [GO:0008020] 0.066459756 1.83531 spindle pole [GO:0000922] 0.066552522 1.834684 negative regulation of cell-cell adhesion [GO:0022408] 0.06662418 1.834201 phosphatidylinositol phosphate kinase activity [GO:0016307] 0.067980828 1.825134 activation of immune response [GO:0002253] 0.06851929 1.821576 regulation of neurological system process [GO:0031644] 0.068651517 1.820706 regulation of synaptic transmission [GO:0050804] 0.068651517 1.820706 regulation of transmission of nerve impulse [GO:0051969] 0.068651517 1.820706 G-protein signaling, coupled to cAMP nucleotide second messenger [GO:0007188] 0.069070863 1.817956 dicarboxylic acid transmembrane transporter activity [GO:0005310] 0.069266868 1.816675 dicarboxylic acid transport [GO:0006835] 0.069266868 1.816675 identical protein binding [GO:0042802] 0.070558521 1.808308 actin filament organization [GO:0007015] 0.070739986 1.807143 mitochondrial respiratory chain [GO:0005746] 0.07145647 1.802566 hydrolase activity [GO:0016787] 0.071990041 1.799181 peptide hormone secretion [GO:0030072] 0.072069195 1.798681 exoribonuclease activity [GO:0004532] 0.072484218 1.796065 exoribonuclease activity, producing 5'-phosphomonoesters [GO:0016896] 0.072484218 1.796065 cytokine and chemokine mediated signaling pathway [GO:0019221] 0.072978705 1.792964 glycogen metabolic process [GO:0005977] 0.074103513 1.785974 glucan metabolic process [GO:0006073] 0.074103513 1.785974 nucleic acid transport [GO:0050657] 0.074163919 1.785601 RNA transport [GO:0050658] 0.074163919 1.785601 establishment of RNA localization [GO:0051236] 0.074163919 1.785601 skeletal muscle fiber development [GO:0048741] 0.074235663 1.785158 muscle fiber development [GO:0048747] 0.074235663 1.785158 lipid catabolic process [GO:0016042] 0.074519719 1.783409 carboxypeptidase activity [GO:0004180] 0.074585526 1.783005 neurotransmitter uptake [GO:0001504] 0.074792404 1.781735 oxidative phosphorylation [GO:0006119] 0.076592965 1.770806 nucleolar part [GO:0044452] 0.077049853 1.768066 RNA localization [GO:0006403] 0.07734239 1.766319 generation of a signal involved in cell-cell signaling [GO:0003001] 0.077879968 1.763122 lipase activity [GO:0016298] 0.078251756 1.760921 nucleotide biosynthetic process [GO:0009165] 0.078624287 1.758725 regulation of synaptic plasticity [GO:0048167] 0.079807296 1.751805 carbohydrate binding [GO:0030246] 0.080369553 1.748546 protein phosphatase regulator activity [GO:0019888] 0.080387011 1.748445 striated muscle contraction [GO:0006941] 0.081210109 1.743707 secondary metabolic process [GO:0019748] 0.081385053 1.742706 cytokinesis [GO:0000910] 0.081479452 1.742166 barbed-end actin filament capping [GO:0051016] 0.081783214 1.740432 actin filament capping [GO:0051693] 0.081783214 1.740432 DNA-dependent ATPase activity [GO:0008094] 0.082442888 1.736684 regulation of S phase [GO:0033261] 0.083835305 1.728854 cellular metal ion homeostasis [GO:0006875] 0.084263759 1.726465 metal ion homeostasis [GO:0055065] 0.084263759 1.726465 cellular carbohydrate metabolic process [GO:0044262] 0.085522255 1.719506 negative regulation of cell migration [GO:0030336] 0.085868117 1.717608 pigmentation during development [GO:0048066] 0.086621544 1.713495 lymphocyte mediated immunity [GO:0002449] 0.087259581 1.710034 structural constituent of cytoskeleton [GO:0005200] 0.088013681 1.70597 carboxylic acid binding [GO:0031406] 0.088061524 1.705713 protein phosphatase inhibitor activity [GO:0004864] 0.088171156 1.705125 peptidase activity [GO:0008233] 0.088358793 1.704119 cell fraction [GO:0000267] 0.088723038 1.702172 fat cell differentiation [GO:0045444] 0.088737103 1.702097 dendrite development [GO:0016358] 0.08913291 1.699989 membrane lipid catabolic process [GO:0046466] 0.089372189 1.698719 phosphorylation [GO:0016310] 0.089841287 1.696236 regulation of neuron differentiation [GO:0045664] 0.089850239 1.696188 cellular calcium ion homeostasis [GO:0006874] 0.090143629 1.694641 calcium ion homeostasis [GO:0055074] 0.090143629 1.694641 detection of external stimulus [GO:0009581] 0.090515503 1.692685 regulation of T cell differentiation [GO:0045580] 0.090520737 1.692657 regulation of lymphocyte differentiation [GO:0045619] 0.090520737 1.692657 glycerolipid metabolic process [GO:0046486] 0.09132996 1.688424 chloride ion binding [GO:0031404] 0.091494111 1.687568 anion binding [GO:0043168] 0.091494111 1.687568 carbohydrate homeostasis [GO:0033500] 0.092003487 1.684923 glucose homeostasis [GO:0042593] 0.092003487 1.684923 sodium ion transport [GO:0006814] 0.092422407 1.682756 chemical homeostasis [GO:0048878] 0.092749652 1.681068 mitotic metaphase/anaphase transition [GO:0007091] 0.09284612 1.680572 regulation of mitotic metaphase/anaphase transition [GO:0030071] 0.09284612 1.680572 transporter activity [GO:0005215] 0.092957602 1.679999 regulation of cytokine biosynthetic process [GO:0042035] 0.093379393 1.677835 cytokine biosynthetic process [GO:0042089] 0.093379393 1.677835 cytokine metabolic process [GO:0042107] 0.093379393 1.677835 eye development [GO:0001654] 0.093486067 1.677289 inositol or phosphatidylinositol phosphatase activity [GO:0004437] 0.093512079 1.677155 positive regulation of cell migration [GO:0030335] 0.093633441 1.676535 nucleotide-sugar metabolic process [GO:0009225] 0.093769669 1.675839 protein kinase activity [GO:0004672] 0.094465249 1.6723 replication fork [GO:0005657] 0.095222921 1.668468 central nervous system neuron development [GO:0021954] 0.095613922 1.6665 cytoplasmic membrane-bounded vesicle lumen [GO:0060205] 0.095861515 1.665257 ribonucleoprotein complex biogenesis and assembly [GO:0022613] 0.096121042 1.663957 protein phosphatase type 2A regulator activity [GO:0008601] 0.096296972 1.663077 positive regulation of multicellular organismal process [GO:0051240] 0.096932257 1.659912 phospholipase activity [GO:0004620] 0.096968154 1.659733 intramolecular oxidoreductase activity [GO:0016860] 0.09704083 1.659372 glycosylceramide metabolic process [GO:0006677] 0.097958591 1.654832 blood vessel morphogenesis [GO:0048514] 0.098031114 1.654475 calmodulin binding [GO:0005516] 0.098329872 1.653005 basal lamina [GO:0005605] 0.099027869 1.649585 membrane fraction [GO:0005624] 0.099226424 1.648616 protein amino acid phosphorylation [GO:0006468] 0.101512995 1.637562 nucleobase, nucleoside, nucleotide and nucleic acid transport [GO:0015931] 0.10157875 1.637248 lytic vacuole [GO:0000323] 0.101752063 1.636418 lysosome [GO:0005764] 0.101752063 1.636418 locomotion [GO:0040011] 0.101781978 1.636275 regulation of cell activation [GO:0050865] 0.101895868 1.635731 leukocyte migration [GO:0050900] 0.103998526 1.62577 mitotic sister chromatid segregation [GO:0000070] 0.104032668 1.62561 maintenance of location [GO:0051235] 0.104290616 1.624399 carbohydrate metabolic process [GO:0005975] 0.105176098 1.620262 mononuclear cell proliferation [GO:0032943] 0.106065916 1.616131 lymphocyte proliferation [GO:0046651] 0.106065916 1.616131 growth factor activity [GO:0008083] 0.106221349 1.615413 microtubule organizing center organization and biogenesis [GO:0031023] 0.106239659 1.615328 centrosome organization and biogenesis [GO:0051297] 0.106239659 1.615328 drug binding [GO:0008144] 0.106499861 1.614127 feeding behavior [GO:0007631] 0.107170959 1.61104 positive regulation of cell differentiation [GO:0045597] 0.107287041 1.610508 cation transport [GO:0006812] 0.108092199 1.606828 vesicle [GO:0031982] 0.108430272 1.605289 AMP-activated protein kinase activity [GO:0004679] 0.108592987 1.604549 sphingolipid biosynthetic process [GO:0030148] 0.1088569 1.603352 adaptive immune response [GO:0002250] 0.109661291 1.599717 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [GO:0002460] 0.109661291 1.599717 organic acid catabolic process [GO:0016054] 0.110980032 1.593804 carboxylic acid catabolic process [GO:0046395] 0.110980032 1.593804 SH3 domain binding [GO:0017124] 0.110999515 1.593717 RNA helicase activity [GO:0003724] 0.111818687 1.590072 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [GO:0016810] 0.112336188 1.58778 metalloexopeptidase activity [GO:0008235] 0.114214024 1.579532 regulation of heart contraction [GO:0008016] 0.115052766 1.575883 phosphatase binding [GO:0019902] 0.115805399 1.572626 somitogenesis [GO:0001756] 0.115837348 1.572488 detection of stimulus involved in sensory perception [GO:0050906] 0.117892925 1.563679 site of polarized growth [GO:0030427] 0.118088031 1.562849 heterotrimeric G-protein complex [GO:0005834] 0.118998332 1.558992 immune response [GO:0006955] 0.121207364 1.549726 kinetochore [GO:0000776] 0.121426775 1.548813 positive regulation of alpha-beta T cell activation [GO:0046635] 0.121482643 1.54858 positive regulation of alpha-beta T cell differentiation [GO:0046638] 0.121482643 1.54858 UDP-glycosyltransferase activity [GO:0008194] 0.121768431 1.547393 vesicular fraction [GO:0042598] 0.121951504 1.546634 positive regulation of cytokine biosynthetic process [GO:0042108] 0.122109111 1.545981 platelet alpha granule lumen [GO:0031093] 0.12467344 1.53545 monovalent inorganic cation transport [GO:0015672] 0.125171956 1.533422 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616] 0.125483141 1.532159 positive regulation of T cell activation [GO:0050870] 0.126349679 1.528656 cell surface [GO:0009986] 0.127312053 1.524788 leukocyte mediated immunity [GO:0002443] 0.127377051 1.524527 gated channel activity [GO:0022836] 0.127608627 1.5236 response to drug [GO:0042493] 0.129058665 1.517824 protein dimerization activity [GO:0046983] 0.129205374 1.517243 cytoskeletal part [GO:0044430] 0.129545457 1.515897 negative regulation of biological process [GO:0048519] 0.129850917 1.51469 regulation of cell differentiation [GO:0045595] 0.13079158 1.510988 regulation of leukocyte activation [GO:0002694] 0.130884852 1.510622 regulation of T cell activation [GO:0050863] 0.130884852 1.510622 regulation of lymphocyte activation [GO:0051249] 0.130884852 1.510622 neuromuscular process [GO:0050905] 0.131029833 1.510053 organ morphogenesis [GO:0009887] 0.131164692 1.509525 serine-type peptidase activity [GO:0008236] 0.131872328 1.506759 serine hydrolase activity [GO:0017171] 0.131872328 1.506759 regulation of cell migration [GO:0030334] 0.132312718 1.505044 cell differentiation [GO:0030154] 0.13364678 1.499875 cellular developmental process [GO:0048869] 0.13364678 1.499875 cell fate determination [GO:0001709] 0.133817008 1.499218 G-protein signaling, coupled to cyclic nucleotide second messenger [GO:0007187] 0.134251021 1.497547 negative regulation of response to external stimulus [GO:0032102] 0.136923922 1.487344 peripheral nervous system development [GO:0007422] 0.137113849 1.486625 regulation of cell motility [GO:0051270] 0.138851211 1.480083 hormone secretion [GO:0046879] 0.139146528 1.478977 cytoplasmic vesicle [GO:0031410] 0.139189946 1.478814 learning and/or memory [GO:0007611] 0.139566603 1.477407 adult behavior [GO:0030534] 0.141261384 1.47111 condensed chromosome kinetochore [GO:0000777] 0.142229392 1.467539 condensed chromosome, pericentric region [GO:0000779] 0.142229392 1.467539 Golgi lumen [GO:0005796] 0.142737095 1.465674 nuclear membrane [GO:0031965] 0.143546036 1.462713 protein tyrosine kinase activity [GO:0004713] 0.144320979 1.459888 phosphatidylinositol metabolic process [GO:0046488] 0.144512505 1.459191 ligand-gated ion channel activity [GO:0015276] 0.144614081 1.458822 ligand-gated channel activity [GO:0022834] 0.144614081 1.458822 cell-matrix adhesion [GO:0007160] 0.145712254 1.454845 macromolecular complex disassembly [GO:0032984] 0.14620366 1.453072 microsome [GO:0005792] 0.14807149 1.446377 immune system process [GO:0002376] 0.148104995 1.446257 cation channel activity [GO:0005261] 0.149701771 1.440586 polysaccharide metabolic process [GO:0005976] 0.149822157 1.44016 cellular polysaccharide metabolic process [GO:0044264] 0.149822157 1.44016 fatty acid metabolic process [GO:0006631] 0.149909926 1.43985 anatomical structure morphogenesis [GO:0009653] 0.150422235 1.438042 positive regulation of macromolecule biosynthetic process [GO:0010557] 0.150832958 1.436596 regulation of membrane potential [GO:0042391] 0.151033019 1.435892 vacuole [GO:0005773] 0.151062708 1.435788 negative regulation of cell activation [GO:0050866] 0.151497935 1.434261 smooth muscle contraction [GO:0006939] 0.151998956 1.432506 oxidoreductase activity, acting on CH-OH group of donors [GO:0016614] 0.15202074 1.43243 amino sugar metabolic process [GO:0006040] 0.152786475 1.429758 glucosamine metabolic process [GO:0006041] 0.152786475 1.429758 N-acetylglucosamine metabolic process [GO:0006044] 0.152786475 1.429758 purine nucleoside monophosphate metabolic process [GO:0009126] 0.152897553 1.429371 purine nucleoside monophosphate biosynthetic process [GO:0009127] 0.152897553 1.429371 purine ribonucleoside monophosphate metabolic process [GO:0009167] 0.152897553 1.429371 purine ribonucleoside monophosphate biosynthetic process [GO:0009168] 0.152897553 1.429371 sister chromatid segregation [GO:0000819] 0.153618308 1.426867 lymphocyte activation [GO:0046649] 0.154706411 1.423103 neuromuscular junction development [GO:0007528] 0.156153983 1.418126 acute inflammatory response [GO:0002526] 0.15646555 1.417059 anion channel activity [GO:0005253] 0.157041594 1.415092 alkali metal ion binding [GO:0031420] 0.159849963 1.405576 positive regulation of cell motility [GO:0051272] 0.160111605 1.404696 photoreceptor cell maintenance [GO:0045494] 0.161082509 1.40144 receptor binding [GO:0005102] 0.16153087 1.399941 protein complex binding [GO:0032403] 0.161657023 1.39952 sodium ion binding [GO:0031402] 0.162513518 1.396668 cell proliferation [GO:0008283] 0.162734139 1.395935 steroid hormone receptor activity [GO:0003707] 0.16284229 1.395576 protein disulfide isomerase activity [GO:0003756] 0.16390841 1.392046 intramolecular oxidoreductase activity, interconverting keto- and enol-groups [GO:0016862] 0.16390841 1.392046 intramolecular oxidoreductase activity, transposing S-S bonds [GO:0016864] 0.16390841 1.392046 peptide secretion [GO:0002790] 0.164481486 1.390156 adult walking behavior [GO:0007628] 0.165705626 1.386135 substrate-specific transmembrane transporter activity [GO:0022891] 0.165890997 1.385528 transferase activity, transferring acyl groups [GO:0016746] 0.166556071 1.383355 axon extension [GO:0048675] 0.166702285 1.382878 fatty acid catabolic process [GO:0009062] 0.167480103 1.380346 DNA packaging [GO:0006323] 0.167571415 1.380049 phosphoprotein binding [GO:0051219] 0.1704684 1.3707 protein domain specific binding [GO:0019904] 0.171010001 1.368966 protein phosphatase binding [GO:0019903] 0.171092832 1.368701 protein polymerization [GO:0051258] 0.171253117 1.368188 cofactor catabolic process [GO:0051187] 0.171473337 1.367485 positive regulation of transport [GO:0051050] 0.171678597 1.36683 vasculature development [GO:0001944] 0.172140365 1.365359 metallopeptidase activity [GO:0008237] 0.17308768 1.362349 cell-substrate adhesion [GO:0031589] 0.173821399 1.360027 protein serine/threonine phosphatase complex [GO:0008287] 0.173892996 1.359801 protein tetramerization [GO:0051262] 0.173917993 1.359722 ribosome assembly [GO:0042255] 0.174677222 1.357327 response to radiation [GO:0009314] 0.175348341 1.355217 organic acid metabolic process [GO:0006082] 0.177818286 1.347503 carboxylic acid metabolic process [GO:0019752] 0.177818286 1.347503 response to stimulus [GO:0050896] 0.178012488 1.3469 photoreceptor activity [GO:0009881] 0.179436474 1.342492 L-ascorbic acid binding [GO:0031418] 0.180430512 1.339431 central nervous system neuron differentiation [GO:0021953] 0.181025393 1.337605 sphingolipid metabolic process [GO:0006665] 0.182145839 1.334177 behavioral interaction between organisms [GO:0051705] 0.182209784 1.333982 cellular lipid metabolic process [GO:0044255] 0.182880925 1.331937 heart looping [GO:0001947] 0.18319266 1.330989 regulation of tube size [GO:0035150] 0.18477649 1.326191 regulation of blood vessel size [GO:0050880] 0.18477649 1.326191 cAMP metabolic process [GO:0046058] 0.185094775 1.32523 NAD binding [GO:0051287] 0.185817174 1.323055 receptor metabolic process [GO:0043112] 0.186394748 1.32132 ATP-dependent RNA helicase activity [GO:0004004] 0.186399333 1.321306 RNA-dependent ATPase activity [GO:0008186] 0.186399333 1.321306 disulfide oxidoreductase activity [GO:0015036] 0.186520933 1.320941 nuclear membrane part [GO:0044453] 0.188268601 1.315718 phospholipid catabolic process [GO:0009395] 0.190385593 1.309439 signal recognition particle, endoplasmic reticulum targeting [GO:0005786] 0.190707821 1.308488 signal recognition particle [GO:0048500] 0.190707821 1.308488 glycogen biosynthetic process [GO:0005978] 0.191400837 1.306446 glucan biosynthetic process [GO:0009250] 0.191400837 1.306446 ribonucleoside metabolic process [GO:0009119] 0.192215896 1.304052 activation of MAPK activity [GO:0000187] 0.192413273 1.303473 regulation of cell adhesion [GO:0030155] 0.192650616 1.302778 positive regulation of MAP kinase activity [GO:0043406] 0.194602025 1.297085 elevation of cytosolic calcium ion concentration [GO:0007204] 0.194679915 1.296858 cytosolic calcium ion homeostasis [GO:0051480] 0.194679915 1.296858 cellular ion homeostasis [GO:0006873] 0.196348684 1.292024 di-, tri-valent inorganic cation homeostasis [GO:0055066] 0.196504032 1.291576 adult locomotory behavior [GO:0008344] 0.197059061 1.289976 regulation of organelle organization and biogenesis [GO:0033043] 0.19808315 1.287032 regulation of epithelial cell proliferation [GO:0050678] 0.198129762 1.286898 structural molecule activity [GO:0005198] 0.198484749 1.285881 growth factor binding [GO:0019838] 0.199303177 1.283539 heart development [GO:0007507] 0.199390334 1.28329 negative regulation of leukocyte activation [GO:0002695] 0.199943277 1.281713 multicellular organismal metabolic process [GO:0044236] 0.199943277 1.281713 negative regulation of T cell activation [GO:0050868] 0.199943277 1.281713 negative regulation of lymphocyte activation [GO:0051250] 0.199943277 1.281713 acetylglucosaminyltransferase activity [GO:0008375] 0.201208401 1.278116 helicase activity [GO:0004386] 0.20146988 1.277375 acyltransferase activity [GO:0008415] 0.202528649 1.27438 transferase activity, transferring groups other than amino-acyl groups [GO:0016747] 0.202528649 1.27438 nuclear lumen [GO:0031981] 0.202742574 1.273777 DNA replication initiation [GO:0006270] 0.203242156 1.272369 insulin-like growth factor binding [GO:0005520] 0.203537056 1.271539 myeloid leukocyte differentiation [GO:0002573] 0.204163449 1.269779 2 iron, 2 sulfur cluster binding [GO:0051537] 0.2045358 1.268734 purine nucleotide biosynthetic process [GO:0006164] 0.206560907 1.263079 JAK-STAT cascade [GO:0007259] 0.208175283 1.258599 central nervous system development [GO:0007417] 0.208959618 1.256431 detection of abiotic stimulus [GO:0009582] 0.209205074 1.255754 retinoid binding [GO:0005501] 0.209273652 1.255565 isoprenoid binding [GO:0019840] 0.209273652 1.255565 positive regulation of biosynthetic process [GO:0009891] 0.210159043 1.253128 glial cell differentiation [GO:0010001] 0.210439194 1.252359 amino acid binding [GO:0016597] 0.210797693 1.251375 positive regulation of leukocyte activation [GO:0002696] 0.212996157 1.245369 positive regulation of cell activation [GO:0050867] 0.212996157 1.245369 positive regulation of lymphocyte activation [GO:0051251] 0.212996157 1.245369 carbon-nitrogen lyase activity [GO:0016840] 0.213021731 1.245299 synaptosome [GO:0019717] 0.213047162 1.24523 inorganic cation transmembrane transporter activity [GO:0022890] 0.213163298 1.244914 actin filament bundle formation [GO:0051017] 0.214532322 1.241199 extracellular structure organization and biogenesis [GO:0043062] 0.214828121 1.240398 aminopeptidase activity [GO:0004177] 0.216464972 1.235983 negative regulation of cell adhesion [GO:0007162] 0.217004192 1.234533 cell-cell adherens junction [GO:0005913] 0.21878327 1.22977 double-strand break repair via homologous recombination [GO:0000724] 0.218986794 1.229227 recombinational repair [GO:0000725] 0.218986794 1.229227 protein binding, bridging [GO:0030674] 0.220247034 1.225872 tyrosine phosphorylation of STAT protein [GO:0007260] 0.221012831 1.223839 S phase [GO:0051320] 0.221310025 1.223052 integrin-mediated signaling pathway [GO:0007229] 0.221409711 1.222788 epithelial cell proliferation [GO:0050673] 0.222431855 1.220087 mitochondrial matrix [GO:0005759] 0.224978133 1.213397 mitochondrial lumen [GO:0031980] 0.224978133 1.213397 organic acid biosynthetic process [GO:0016053] 0.22503096 1.213259 carboxylic acid biosynthetic process [GO:0046394] 0.22503096 1.213259 microtubule organizing center part [GO:0044450] 0.225610284 1.211744 cellular biosynthetic process [GO:0044249] 0.225935996 1.210894 microtubule cytoskeleton organization and biogenesis [GO:0000226] 0.226515399 1.209384 phosphatase inhibitor activity [GO:0019212] 0.226652138 1.209028 positive regulation of gene-specific transcription [GO:0043193] 0.226652138 1.209028 fatty acid binding [GO:0005504] 0.228571108 1.204048 phospholipase C activity [GO:0004629] 0.229041531 1.202832 small ribosomal subunit [GO:0015935] 0.229447181 1.201784 negative regulation of cellular process [GO:0048523] 0.229456847 1.201759 G-protein signaling, adenylate cyclase activating pathway [GO:0007189] 0.229483217 1.201691 ion transport [GO:0006811] 0.229998406 1.200363 intercalated disc [GO:0014704] 0.23189248 1.195498 cell motility [GO:0006928] 0.232064713 1.195057 localization of cell [GO:0051674] 0.232064713 1.195057 copper ion binding [GO:0005507] 0.232591594 1.19371 myeloid leukocyte activation [GO:0002274] 0.233007855 1.192646 embryonic skeletal development [GO:0048706] 0.233149471 1.192285 transferase activity, transferring nitrogenous groups [GO:0016769] 0.23404097 1.190014 acetyl-CoA metabolic process [GO:0006084] 0.234374092 1.189167 regulation of cyclin-dependent protein kinase activity [GO:0000079] 0.234863041 1.187925 respiratory electron transport chain [GO:0022904] 0.234969825 1.187654 monovalent inorganic cation transmembrane transporter activity [GO:0015077] 0.235191256 1.187092 angiogenesis [GO:0001525] 0.236645829 1.183412 purine ribonucleotide biosynthetic process [GO:0009152] 0.236845365 1.182909 cofactor binding [GO:0048037] 0.237080844 1.182315 ion homeostasis [GO:0050801] 0.237487567 1.18129 histone acetyltransferase complex [GO:0000123] 0.237799754 1.180504 pigment metabolic process [GO:0042440] 0.239552654 1.176106 lipid kinase activity [GO:0001727] 0.240512633 1.173706 leukocyte activation [GO:0045321] 0.240767853 1.17307 muscle cell differentiation [GO:0042692] 0.241567773 1.171077 embryonic pattern specification [GO:0009880] 0.242263224 1.169349 regulation of actin filament-based process [GO:0032970] 0.242268872 1.169335 blood vessel development [GO:0001568] 0.243250342 1.166901 membrane lipid metabolic process [GO:0006643] 0.243510327 1.166258 deaminase activity [GO:0019239] 0.243902959 1.165287 icosanoid metabolic process [GO:0006690] 0.24406871 1.164877 icosanoid biosynthetic process [GO:0046456] 0.24406871 1.164877 mismatched DNA binding [GO:0030983] 0.245160943 1.162183 carbohydrate transport [GO:0008643] 0.24531448 1.161805 regulation of mononuclear cell proliferation [GO:0032944] 0.246988944 1.157694 regulation of lymphocyte proliferation [GO:0050670] 0.246988944 1.157694 T cell activation [GO:0042110] 0.247299452 1.156934 PDZ domain binding [GO:0030165] 0.248770239 1.153342 glutamate metabolic process [GO:0006536] 0.24882647 1.153204 negative regulation of neurogenesis [GO:0050768] 0.250869674 1.14824 protein phosphatase type 2A complex [GO:0000159] 0.251256281 1.147303 collagen metabolic process [GO:0032963] 0.25303056 1.143019 nuclear envelope [GO:0005635] 0.253391063 1.142151 peptide biosynthetic process [GO:0043043] 0.253524252 1.141831 cell adhesion [GO:0007155] 0.253760621 1.141263 biological adhesion [GO:0022610] 0.253760621 1.141263 polysaccharide biosynthetic process [GO:0000271] 0.255509937 1.137068 cellular polysaccharide biosynthetic process [GO:0033692] 0.255509937 1.137068 neuron apoptosis [GO:0051402] 0.256274692 1.13524 cAMP biosynthetic process [GO:0006171] 0.256380815 1.134987 myoblast development [GO:0048627] 0.256564043 1.13455 myoblast maturation [GO:0048628] 0.256564043 1.13455 cellular chemical homeostasis [GO:0055082] 0.257499836 1.13232 ligand-dependent nuclear receptor activity [GO:0004879] 0.258421796 1.130129 camera-type eye development [GO:0043010] 0.258567632 1.129783 fibroblast growth factor receptor signaling pathway [GO:0008543] 0.259761753 1.126954 CoA-ligase activity [GO:0016405] 0.260305722 1.125669 ligase activity, forming carbon-sulfur bonds [GO:0016877] 0.260305722 1.125669 acid-thiol ligase activity [GO:0016878] 0.260305722 1.125669 cytoskeletal protein binding [GO:0008092] 0.261349144 1.123208 negative regulation of DNA metabolic process [GO:0051053] 0.261405916 1.123074 alpha-beta T cell activation [GO:0046631] 0.261691261 1.122403 alpha-beta T cell differentiation [GO:0046632] 0.261691261 1.122403 regulation of alpha-beta T cell activation [GO:0046634] 0.261691261 1.122403 regulation of alpha-beta T cell differentiation [GO:0046637] 0.261691261 1.122403 phosphotransferase activity, alcohol group as acceptor [GO:0016773] 0.262371202 1.120804 neutral lipid metabolic process [GO:0006638] 0.26272138 1.119982 acylglycerol metabolic process [GO:0006639] 0.26272138 1.119982 triacylglycerol metabolic process [GO:0006641] 0.26272138 1.119982 regulation of nucleotide metabolic process [GO:0006140] 0.262848947 1.119683 regulation of cyclic nucleotide metabolic process [GO:0030799] 0.262848947 1.119683 regulation of cAMP metabolic process [GO:0030814] 0.262848947 1.119683 NADH dehydrogenase activity [GO:0003954] 0.263563891 1.118007 NADH dehydrogenase (ubiquinone) activity [GO:0008137] 0.263563891 1.118007 NADH dehydrogenase (quinone) activity [GO:0050136] 0.263563891 1.118007 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [GO:0045935] 0.26471147 1.115324 sphingolipid catabolic process [GO:0030149] 0.265482619 1.113526 electron carrier activity [GO:0009055] 0.267225726 1.109474 soluble fraction [GO:0005625] 0.26853702 1.106438 ribosomal subunit [GO:0033279] 0.26853717 1.106438 regulation of cytoskeleton organization and biogenesis [GO:0051493] 0.269068037 1.105211 primary metabolic process [GO:0044238] 0.269096357 1.105146 basement membrane [GO:0005604] 0.269786605 1.103554 signal transduction [GO:0007165] 0.269933785 1.103215 nerve-nerve synaptic transmission [GO:0007270] 0.270089256 1.102857 transcription activator activity [GO:0016563] 0.270104286 1.102822 symporter activity [GO:0015293] 0.271357445 1.099942 anti-apoptosis [GO:0006916] 0.271822812 1.098874 intracellular [GO:0005622] 0.271885512 1.098731 negative regulation of multicellular organismal process [GO:0051241] 0.273004778 1.096169 cell cycle checkpoint [GO:0000075] 0.274172461 1.093504 clathrin-coated vesicle [GO:0030136] 0.274898688 1.091851 heat shock protein binding [GO:0031072] 0.275286178 1.09097 platelet alpha granule [GO:0031091] 0.276506806 1.0882 positive regulation of growth [GO:0045927] 0.278076648 1.08465 visual behavior [GO:0007632] 0.278280366 1.08419 cholesterol homeostasis [GO:0042632] 0.279039647 1.082479 sterol homeostasis [GO:0055092] 0.279039647 1.082479 protein homodimerization activity [GO:0042803] 0.28099594 1.078085 spindle microtubule [GO:0005876] 0.283274724 1.072992 steroid binding [GO:0005496] 0.285676839 1.067654 nucleocytoplasmic transporter activity [GO:0005487] 0.286157397 1.066589 regulation of axon extension [GO:0030516] 0.286223339 1.066443 amine transmembrane transporter activity [GO:0005275] 0.286926742 1.064888 amino acid transmembrane transporter activity [GO:0015171] 0.286926742 1.064888 negative regulation of cellular biosynthetic process [GO:0031327] 0.289418073 1.059399 vascular process in circulatory system [GO:0003018] 0.290946598 1.056047 cell soma [GO:0043025] 0.29125359 1.055376 chemotaxis [GO:0006935] 0.291631836 1.054549 taxis [GO:0042330] 0.291631836 1.054549 eye morphogenesis [GO:0048592] 0.294705723 1.047854 regulation of response to external stimulus [GO:0032101] 0.295959226 1.045138 racemase and epimerase activity [GO:0016854] 0.298252924 1.040187 polysome [GO:0005844] 0.298480089 1.039698 chloride channel activity [GO:0005254] 0.299167254 1.038221 ceramide metabolic process [GO:0006672] 0.299489211 1.037529 sphingoid metabolic process [GO:0046519] 0.299489211 1.037529 regulation of coagulation [GO:0050818] 0.300957519 1.034382 actin filament depolymerization [GO:0030042] 0.3017411 1.032707 regulation of actin filament depolymerization [GO:0030834] 0.3017411 1.032707 negative regulation of actin filament depolymerization [GO:0030835] 0.3017411 1.032707 protein depolymerization [GO:0051261] 0.3017411 1.032707 microvillus [GO:0005902] 0.302280213 1.031556 nuclear chromosome part [GO:0044454] 0.304679569 1.02645 ion binding [GO:0043167] 0.304778448 1.02624 heme binding [GO:0020037] 0.305241358 1.025258 tetrapyrrole binding [GO:0046906] 0.305241358 1.025258 metabolic compound salvage [GO:0043094] 0.305879349 1.023907 metalloendopeptidase activity [GO:0004222] 0.30633394 1.022945 low-density lipoprotein receptor binding [GO:0050750] 0.30672842 1.022111 purine nucleotide metabolic process [GO:0006163] 0.307419624 1.020651 mitochondrial respiratory chain complex I [GO:0005747] 0.309059189 1.017198 mitochondrial electron transport, NADH to ubiquinone [GO:0006120] 0.309059189 1.017198 NADH dehydrogenase complex [GO:0030964] 0.309059189 1.017198 ATP synthesis coupled electron transport [GO:0042773] 0.309059189 1.017198 organelle ATP synthesis coupled electron transport [GO:0042775] 0.309059189 1.017198 respiratory chain complex I [GO:0045271] 0.309059189 1.017198 regulation of angiogenesis [GO:0045765] 0.309287198 1.016719 isoprenoid metabolic process [GO:0006720] 0.310598978 1.013966 protein disulfide oxidoreductase activity [GO:0015035] 0.310599714 1.013964 coreceptor activity [GO:0015026] 0.310711376 1.01373 hydrogen transport [GO:0006818] 0.311475641 1.012131 nucleobase, nucleoside and nucleotide metabolic process [GO:0055086] 0.311540557 1.011995 anatomical structure formation [GO:0048646] 0.311767257 1.011521 peptidyl-amino acid modification [GO:0018193] 0.311961233 1.011115 membrane [GO:0016020] 0.312772941 1.009421 endoplasmic reticulum [GO:0005783] 0.314273962 1.006294 cation binding [GO:0043169] 0.31551282 1.003722 regulation of protein binding [GO:0043393] 0.317908323 0.998765 carbohydrate catabolic process [GO:0016052] 0.318426997 0.997696 cellular carbohydrate catabolic process [GO:0044275] 0.318426997 0.997696 receptor complex [GO:0043235] 0.318431581 0.997686 negative regulation of cell proliferation [GO:0008285] 0.318615544 0.997307 developmental maturation [GO:0021700] 0.318905441 0.99671 detection of stimulus [GO:0051606] 0.319956935 0.994546 organelle part [GO:0044422] 0.321566284 0.991244 response to temperature stimulus [GO:0009266] 0.322130063 0.99009 molecular adaptor activity [GO:0060090] 0.322993651 0.988325 scavenger receptor activity [GO:0005044] 0.32403751 0.986195 ensheathment of neurons [GO:0007272] 0.324414046 0.985428 axon ensheathment [GO:0008366] 0.324414046 0.985428 myelination [GO:0042552] 0.324414046 0.985428 terpenoid metabolic process [GO:0006721] 0.325508111 0.983202 purine ribonucleotide metabolic process [GO:0009150] 0.325972438 0.982259 nucleotide-excision repair [GO:0006289] 0.326595986 0.980993 positive regulation of biological process [GO:0048518] 0.327186446 0.979797 protein heterodimerization activity [GO:0046982] 0.327337236 0.979491 spindle [GO:0005819] 0.327532446 0.979096 manganese ion binding [GO:0030145] 0.328620285 0.976897 nucleoside phosphate metabolic process [GO:0006753] 0.330132838 0.973846 nucleotide metabolic process [GO:0009117] 0.330132838 0.973846 oxidation reduction [GO:0055114] 0.331067831 0.971965 positive regulation of cellular metabolic process [GO:0031325] 0.331163382 0.971773 amino acid catabolic process [GO:0009063] 0.33129281 0.971513 hormone activity [GO:0005179] 0.332272163 0.969547 leukocyte differentiation [GO:0002521] 0.33296543 0.968158 amine catabolic process [GO:0009310] 0.335387187 0.96332 nitrogen compound catabolic process [GO:0044270] 0.335387187 0.96332 fatty acid biosynthetic process [GO:0006633] 0.336387728 0.961327 nucleotide-excision repair, DNA gap filling [GO:0006297] 0.337053411 0.960004 ATPase activity [GO:0016887] 0.337562732 0.958992 ATPase activity, coupled [GO:0042623] 0.338793429 0.956552 chromatin silencing [GO:0006342] 0.338938469 0.956265 heterochromatin formation [GO:0031507] 0.338938469 0.956265 negative regulation of gene expression, epigenetic [GO:0045814] 0.338938469 0.956265 endopeptidase activity [GO:0004175] 0.339167913 0.955811 positive regulation of transcription [GO:0045941] 0.340227517 0.953716 cyclin-dependent protein kinase activity [GO:0004693] 0.342246329 0.949736 neuropeptide hormone activity [GO:0005184] 0.342534533 0.949169 regulation of developmental process [GO:0050793] 0.342952987 0.948347 female pregnancy [GO:0007565] 0.343461863 0.947347 RNA catabolic process [GO:0006401] 0.343612252 0.947052 nucleoplasm [GO:0005654] 0.343984085 0.946323 response to chemical stimulus [GO:0042221] 0.344322366 0.945659 cellular metabolic process [GO:0044237] 0.345142619 0.944053 polypeptide N-acetylgalactosaminyltransferase activity [GO:0004653] 0.346551255 0.9413 peptide receptor activity [GO:0001653] 0.347490131 0.939469 peptide receptor activity, G-protein coupled [GO:0008528] 0.347490131 0.939469 nuclear part [GO:0044428] 0.348270441 0.937949 lipid particle [GO:0005811] 0.348369041 0.937758 peptide transport [GO:0015833] 0.34874175 0.937033 transcription from RNA polymerase III promoter [GO:0006383] 0.349010165 0.936511 'de novo' protein folding [GO:0006458] 0.352409211 0.929926 'de novo' posttranslational protein folding [GO:0051084] 0.352409211 0.929926 chaperone cofactor-dependent protein folding [GO:0051085] 0.352409211 0.929926 embryonic development [GO:0009790] 0.353164476 0.928469 coenzyme binding [GO:0050662] 0.354649047 0.925609 intracellular organelle part [GO:0044446] 0.354980278 0.924972 membrane part [GO:0044425] 0.355419707 0.924128 regulation of MAPKKK cascade [GO:0043408] 0.355984865 0.923043 negative regulation of cytoskeleton organization and biogenesis [GO:0051494] 0.356342712 0.922356 glucose metabolic process [GO:0006006] 0.357019138 0.92106 ribonucleotide binding [GO:0032553] 0.357144961 0.920819 purine ribonucleotide binding [GO:0032555] 0.357144961 0.920819 negative regulation of cellular component organization and biogenesis [GO:0051129] 0.358740307 0.917768 peptide binding [GO:0042277] 0.360231449 0.914924 homophilic cell adhesion [GO:0007156] 0.360807108 0.913828 mitotic chromosome condensation [GO:0007076] 0.361627844 0.912268 chromosome condensation [GO:0030261] 0.361627844 0.912268 3'-5' exonuclease activity [GO:0008408] 0.363000504 0.909663 porphyrin metabolic process [GO:0006778] 0.363211248 0.909263 tetrapyrrole metabolic process [GO:0033013] 0.363211248 0.909263 heme metabolic process [GO:0042168] 0.363211248 0.909263 preassembly of GPI anchor in ER membrane [GO:0016254] 0.363679213 0.908377 transport [GO:0006810] 0.364124521 0.907534 transaminase activity [GO:0008483] 0.365336707 0.905243 phosphoinositide metabolic process [GO:0030384] 0.366007565 0.903977 phosphoinositide 3-kinase cascade [GO:0014065] 0.366213944 0.903588 H4/H2A histone acetyltransferase complex [GO:0043189] 0.366213944 0.903588 adenyl ribonucleotide binding [GO:0032559] 0.36782971 0.900546 response to UV [GO:0009411] 0.368292047 0.899677 inositol or phosphatidylinositol kinase activity [GO:0004428] 0.368875008 0.898583 dephosphorylation [GO:0016311] 0.369206384 0.897961 protein complex disassembly [GO:0043241] 0.369397815 0.897602 cellular protein complex disassembly [GO:0043624] 0.369397815 0.897602 mitochondrial membrane part [GO:0044455] 0.369411796 0.897576 transmembrane receptor protein tyrosine kinase activity [GO:0004714] 0.370512068 0.895515 DNA integrity checkpoint [GO:0031570] 0.373789643 0.889397 central nervous system neuron axonogenesis [GO:0021955] 0.373884045 0.889222 voltage-gated ion channel activity [GO:0005244] 0.375421505 0.886364 voltage-gated channel activity [GO:0022832] 0.375421505 0.886364 tricarboxylic acid cycle [GO:0006099] 0.375494406 0.886229 coenzyme catabolic process [GO:0009109] 0.375494406 0.886229 acetyl-CoA catabolic process [GO:0046356] 0.375494406 0.886229 regulation of mitosis [GO:0007088] 0.376360863 0.884621 galactosyltransferase activity [GO:0008378] 0.376462676 0.884433 UDP-galactosyltransferase activity [GO:0035250] 0.376462676 0.884433 ATP binding [GO:0005524] 0.377842207 0.881879 metal ion transmembrane transporter activity [GO:0046873] 0.37798273 0.881619 lipid biosynthetic process [GO:0008610] 0.379357771 0.87908 macrophage differentiation [GO:0030225] 0.379681337 0.878484 cellular di-, tri-valent inorganic cation homeostasis [GO:0030005] 0.380656004 0.876688 auxiliary transport protein activity [GO:0015457] 0.38071828 0.876574 channel regulator activity [GO:0016247] 0.38071828 0.876574 protein amino acid acetylation [GO:0006473] 0.381135449 0.875806 hydrogen ion transmembrane transporter activity [GO:0015078] 0.382158048 0.873927 telencephalon development [GO:0021537] 0.382676708 0.872975 vasculogenesis [GO:0001570] 0.38442972 0.869763 localization [GO:0051179] 0.38484331 0.869007 reproductive structure development [GO:0048608] 0.386585983 0.865825 cellular cation homeostasis [GO:0030003] 0.387629799 0.863924 enzyme linked receptor protein signaling pathway [GO:0007167] 0.388838338 0.861726 RNA polymerase II transcription factor activity, enhancer binding [GO:0003705] 0.390522502 0.85867 brain development [GO:0007420] 0.390785983 0.858193 vascular endothelial growth factor receptor activity [GO:0005021] 0.390840413 0.858094 N-acetyltransferase activity [GO:0008080] 0.391881923 0.856209 extrinsic to plasma membrane [GO:0019897] 0.394857461 0.850841 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [GO:0016811] 0.396512083 0.847867 transmembrane receptor protein kinase activity [GO:0019199] 0.397248555 0.846545 spliceosome assembly [GO:0000245] 0.397864454 0.845441 hormone metabolic process [GO:0042445] 0.397962916 0.845265 cellular component organization and biogenesis [GO:0016043] 0.400072268 0.841492 metabolic process [GO:0008152] 0.400741715 0.840297 transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] 0.401378986 0.839161 ribonuclease activity [GO:0004540] 0.402951976 0.836361 damaged DNA binding [GO:0003684] 0.403495993 0.835394 cell projection organization and biogenesis [GO:0030030] 0.403686684 0.835055 cell part morphogenesis [GO:0032990] 0.403686684 0.835055 cell projection morphogenesis [GO:0048858] 0.403686684 0.835055 hydrogen ion transporting ATP synthase activity, rotational mechanism [GO:0046933] 0.403733272 0.834972 unfolded protein binding [GO:0051082] 0.403797335 0.834859 metallocarboxypeptidase activity [GO:0004181] 0.404083815 0.83435 response to hydrogen peroxide [GO:0042542] 0.404561779 0.833502 regulation of action potential [GO:0001508] 0.40678897 0.829558 pyridoxal phosphate binding [GO:0030170] 0.407781348 0.827804 positive regulation of metabolic process [GO:0009893] 0.408342124 0.826815 electron transport [GO:0006118] 0.409919497 0.824035 regulation of cell cycle process [GO:0010564] 0.410483305 0.823043 regulated secretory pathway [GO:0045055] 0.411693195 0.820918 lyase activity [GO:0016829] 0.413750434 0.817312 regulation of neuron apoptosis [GO:0043523] 0.415225329 0.814733 nucleobase, nucleoside and nucleotide biosynthetic process [GO:0034404] 0.415947238 0.813472 protein kinase inhibitor activity [GO:0004860] 0.416103855 0.813199 transferase activity, transferring hexosyl groups [GO:0016758] 0.41661653 0.812305 myoblast differentiation [GO:0045445] 0.418887694 0.808352 intracellular part [GO:0044424] 0.419351267 0.807547 chromatin assembly [GO:0031497] 0.420972137 0.804736 carbohydrate biosynthetic process [GO:0016051] 0.422888243 0.801421 proton-transporting two-sector ATPase complex [GO:0016469] 0.423515397 0.800337 adenyl nucleotide binding [GO:0030554] 0.425803108 0.796394 amino acid derivative metabolic process [GO:0006575] 0.427105573 0.794154 voltage-gated anion channel activity [GO:0008308] 0.428215982 0.792248 purine nucleotide binding [GO:0017076] 0.430327463 0.788631 tube morphogenesis [GO:0035239] 0.430693879 0.788005 regulation of gene-specific transcription [GO:0032583] 0.436182876 0.778655 collagen catabolic process [GO:0030574] 0.438405398 0.774889 multicellular organismal catabolic process [GO:0044243] 0.438405398 0.774889 multicellular organismal protein catabolic process [GO:0044254] 0.438405398 0.774889 protein digestion [GO:0044256] 0.438405398 0.774889 multicellular organismal macromolecule metabolic process [GO:0044259] 0.438405398 0.774889 multicellular organismal macromolecule catabolic process [GO:0044266] 0.438405398 0.774889 multicellular organismal protein metabolic process [GO:0044268] 0.438405398 0.774889 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor [GO:0016655] 0.438539983 0.774661 segmentation [GO:0035282] 0.440831571 0.77079 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines [GO:0016814] 0.442717974 0.767612 meiotic recombination [GO:0007131] 0.442907265 0.767293 aspartic-type endopeptidase activity [GO:0004190] 0.444442737 0.764713 SH3/SH2 adaptor activity [GO:0005070] 0.445227163 0.763396 morphogenesis of a branching structure [GO:0001763] 0.445440265 0.763039 isomerase activity [GO:0016853] 0.446205083 0.761757 response to nutrient [GO:0007584] 0.447491831 0.759603 pigment biosynthetic process [GO:0046148] 0.449267185 0.756637 cytosolic part [GO:0044445] 0.450130438 0.755198 signal sequence binding [GO:0005048] 0.451630496 0.7527 cation homeostasis [GO:0055080] 0.451920756 0.752217 positive regulation of transcription from RNA polymerase II promoter [GO:0045944] 0.453552673 0.749505 regulation of tissue remodeling [GO:0034103] 0.455422923 0.746405 positive regulation of tissue remodeling [GO:0034105] 0.455422923 0.746405 regulation of bone remodeling [GO:0046850] 0.455422923 0.746405 positive regulation of bone remodeling [GO:0046852] 0.455422923 0.746405 potassium ion binding [GO:0030955] 0.455918413 0.745585 cell-cell adhesion [GO:0016337] 0.456022367 0.745413 hydrolase activity, acting on ester bonds [GO:0016788] 0.458297979 0.741652 rough endoplasmic reticulum [GO:0005791] 0.458453222 0.741396 regulation of protein kinase activity [GO:0045859] 0.459747837 0.739262 tissue homeostasis [GO:0001894] 0.460077794 0.738719 multicellular organismal homeostasis [GO:0048871] 0.460077794 0.738719 water-soluble vitamin metabolic process [GO:0006767] 0.460713339 0.737673 oxygen and reactive oxygen species metabolic process [GO:0006800] 0.461246279 0.736796 substrate-specific transporter activity [GO:0022892] 0.461688632 0.736069 cell maturation [GO:0048469] 0.463637764 0.73287 sterol biosynthetic process [GO:0016126] 0.464702779 0.731125 inositol or phosphatidylinositol phosphodiesterase activity [GO:0004434] 0.465119621 0.730443 phosphoinositide phospholipase C activity [GO:0004435] 0.465119621 0.730443 regulation of cellular component organization and biogenesis [GO:0051128] 0.466615323 0.727997 transferase activity, transferring glycosyl groups [GO:0016757] 0.467840015 0.725998 neural crest cell development [GO:0014032] 0.468140887 0.725507 neural crest cell differentiation [GO:0014033] 0.468140887 0.725507 outer membrane [GO:0019867] 0.469195348 0.723789 regulation of ossification [GO:0030278] 0.46959585 0.723137 positive regulation of ossification [GO:0045778] 0.46959585 0.723137 pH reduction [GO:0045851] 0.472374916 0.71862 intracellular pH reduction [GO:0051452] 0.472374916 0.71862 regulation of actin cytoskeleton organization and biogenesis [GO:0032956] 0.472535259 0.71836 nitric oxide biosynthetic process [GO:0006809] 0.473218319 0.717252 nitric oxide metabolic process [GO:0046209] 0.473218319 0.717252 extracellular matrix part [GO:0044420] 0.473413266 0.716937 myotube differentiation [GO:0014902] 0.475483495 0.713586 G-protein-coupled receptor binding [GO:0001664] 0.475505253 0.71355 cholesterol biosynthetic process [GO:0006695] 0.475798465 0.713076 neurotransmitter secretion [GO:0007269] 0.475950526 0.712831 syncytium formation by plasma membrane fusion [GO:0000768] 0.477826995 0.709802 syncytium formation [GO:0006949] 0.477826995 0.709802 myoblast fusion [GO:0007520] 0.477826995 0.709802 plasma membrane fusion [GO:0045026] 0.477826995 0.709802 negative regulation of axonogenesis [GO:0050771] 0.477826995 0.709802 calcium-dependent phospholipid binding [GO:0005544] 0.478298001 0.709043 N-acyltransferase activity [GO:0016410] 0.479199084 0.707591 integrin complex [GO:0008305] 0.480335687 0.705763 hindbrain development [GO:0030902] 0.480792414 0.705029 establishment of localization [GO:0051234] 0.484397678 0.699247 translation elongation factor activity [GO:0003746] 0.485164093 0.698021 ER-nuclear signaling pathway [GO:0006984] 0.485245703 0.69789 aminoglycan metabolic process [GO:0006022] 0.487856543 0.693722 glycosaminoglycan metabolic process [GO:0030203] 0.487856543 0.693722 enzyme regulator activity [GO:0030234] 0.489734845 0.690731 peptidyl-tyrosine phosphorylation [GO:0018108] 0.489740578 0.690721 peptidyl-tyrosine modification [GO:0018212] 0.489740578 0.690721 protein serine/threonine phosphatase activity [GO:0004722] 0.492970435 0.685592 pigmentation [GO:0043473] 0.494352258 0.683403 exonuclease activity [GO:0004527] 0.494615123 0.682987 M phase [GO:0000279] 0.4951504 0.68214 cell recognition [GO:0008037] 0.495408171 0.681732 regulation of cell morphogenesis [GO:0022604] 0.498364929 0.677065 glucose transport [GO:0015758] 0.49889715 0.676226 lipid modification [GO:0030258] 0.499335805 0.675535 regulation of DNA metabolic process [GO:0051052] 0.499640024 0.675056 1-phosphatidylinositol-3-kinase activity [GO:0016303] 0.502009809 0.671331 phosphoinositide 3-kinase activity [GO:0035004] 0.502009809 0.671331 positive regulation of transcription, DNA-dependent [GO:0045893] 0.502082054 0.671217 positive regulation of RNA metabolic process [GO:0051254] 0.502082054 0.671217 response to endogenous stimulus [GO:0009719] 0.502898969 0.669935 mitotic cell cycle checkpoint [GO:0007093] 0.508487046 0.661195 regulation of chromosome organization and biogenesis [GO:0033044] 0.510628971 0.657859 DNA damage checkpoint [GO:0000077] 0.513152561 0.653937 regulation of MAP kinase activity [GO:0043405] 0.513819882 0.652901 lymphocyte differentiation [GO:0030098] 0.514185956 0.652334 positive regulation of cell cycle [GO:0045787] 0.514374518 0.652041 apoptotic program [GO:0008632] 0.514971286 0.651117 glycolysis [GO:0006096] 0.515171692 0.650806 regulation of kinase activity [GO:0043549] 0.515450704 0.650374 nucleoside-triphosphatase activity [GO:0017111] 0.515715474 0.649964 kinase inhibitor activity [GO:0019210] 0.517882318 0.646613 anterior/posterior pattern formation [GO:0009952] 0.517956293 0.646499 glucose catabolic process [GO:0006007] 0.519908556 0.643486 metal ion binding [GO:0046872] 0.520704755 0.642259 proton transport [GO:0015992] 0.521731558 0.640679 integrin binding [GO:0005178] 0.523124067 0.638537 female gonad development [GO:0008585] 0.523405382 0.638105 ATP metabolic process [GO:0046034] 0.523460478 0.63802 snRNA metabolic process [GO:0016073] 0.524377629 0.636612 snRNA processing [GO:0016180] 0.524377629 0.636612 integrator complex [GO:0032039] 0.524377629 0.636612 myosin complex [GO:0016459] 0.524450547 0.6365 blastocyst development [GO:0001824] 0.525537829 0.634832 negative regulation of DNA replication [GO:0008156] 0.52679047 0.632913 phospholipid metabolic process [GO:0006644] 0.526982325 0.632619 brush border [GO:0005903] 0.527893706 0.631225 positive regulation of endocytosis [GO:0045807] 0.527893706 0.631225 biogenic amine metabolic process [GO:0006576] 0.534320108 0.621425 cellular component assembly [GO:0022607] 0.535438755 0.619725 meiosis I [GO:0007127] 0.536371721 0.618309 L-amino acid transmembrane transporter activity [GO:0015179] 0.536445332 0.618197 M phase of mitotic cell cycle [GO:0000087] 0.537039721 0.617296 mitosis [GO:0007067] 0.537039721 0.617296 kinase activity [GO:0016301] 0.538371021 0.615278 immune effector process [GO:0002252] 0.538696531 0.614785 T cell differentiation [GO:0030217] 0.539247951 0.613951 sensory organ development [GO:0007423] 0.539468825 0.613616 vitamin metabolic process [GO:0006766] 0.54125702 0.610913 urogenital system development [GO:0001655] 0.541295358 0.610855 regulation of fatty acid metabolic process [GO:0019217] 0.542745212 0.608667 transcription coactivator activity [GO:0003713] 0.543036666 0.608227 ribonucleotide biosynthetic process [GO:0009260] 0.543528232 0.607486 response to hypoxia [GO:0001666] 0.545225271 0.60493 calcium-mediated signaling [GO:0019722] 0.545878203 0.603948 receptor signaling protein serine/threonine kinase activity [GO:0004702] 0.54689585 0.602418 extrinsic to membrane [GO:0019898] 0.547459047 0.601572 negative regulation of biosynthetic process [GO:0009890] 0.549779151 0.598091 pyrophosphatase activity [GO:0016462] 0.551626455 0.595325 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [GO:0016818] 0.551626455 0.595325 alcohol metabolic process [GO:0006066] 0.551955978 0.594832 organellar small ribosomal subunit [GO:0000314] 0.552064121 0.59467 mitochondrial small ribosomal subunit [GO:0005763] 0.552064121 0.59467 insoluble fraction [GO:0005626] 0.552437668 0.594111 sterol binding [GO:0032934] 0.552901099 0.593419 potassium ion transport [GO:0006813] 0.553867502 0.591975 cofactor metabolic process [GO:0051186] 0.556554435 0.587967 ATP biosynthetic process [GO:0006754] 0.556793163 0.587611 energy coupled proton transport, down electrochemical gradient [GO:0015985] 0.556793163 0.587611 ATP synthesis coupled proton transport [GO:0015986] 0.556793163 0.587611 hydrogen ion transporting ATPase activity, rotational mechanism [GO:0046961] 0.556793163 0.587611 endoplasmic reticulum lumen [GO:0005788] 0.558571341 0.584965 cytoplasmic vesicle part [GO:0044433] 0.558891261 0.584489 thiolester hydrolase activity [GO:0016790] 0.559452613 0.583655 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184] 0.559580531 0.583465 nuclear-transcribed mRNA catabolic process [GO:0000956] 0.559580531 0.583465 mRNA catabolic process [GO:0006402] 0.559580531 0.583465 response to carbohydrate stimulus [GO:0009743] 0.560852386 0.581576 response to hexose stimulus [GO:0009746] 0.560852386 0.581576 response to glucose stimulus [GO:0009749] 0.560852386 0.581576 response to monosaccharide stimulus [GO:0034284] 0.560852386 0.581576 vacuole organization and biogenesis [GO:0007033] 0.560878149 0.581538 actin polymerization and/or depolymerization [GO:0008154] 0.562476218 0.579167 secondary active transmembrane transporter activity [GO:0015291] 0.563050746 0.578316 organelle envelope [GO:0031967] 0.56708587 0.572349 response to abiotic stimulus [GO:0009628] 0.567307397 0.572022 fatty acid oxidation [GO:0019395] 0.567454641 0.571804 protein import into nucleus, translocation [GO:0000060] 0.568297183 0.570561 epidermis development [GO:0008544] 0.568331716 0.57051 adenosine deaminase activity [GO:0004000] 0.569379174 0.568966 hexose transport [GO:0008645] 0.569652026 0.568564 monosaccharide transport [GO:0015749] 0.569652026 0.568564 development of primary female sexual characteristics [GO:0046545] 0.571387374 0.566009 female sex differentiation [GO:0046660] 0.571387374 0.566009 negative regulation of developmental process [GO:0051093] 0.573385054 0.563073 peptide hormone processing [GO:0016486] 0.574477793 0.561469 protein folding [GO:0006457] 0.575348634 0.560192 clathrin coat [GO:0030118] 0.575495345 0.559977 intracellular protein transport [GO:0006886] 0.575910013 0.559369 kinase binding [GO:0019900] 0.577100165 0.557625 tube development [GO:0035295] 0.580329796 0.552903 mRNA polyadenylation [GO:0006378] 0.580804997 0.552209 RNA polyadenylation [GO:0043631] 0.580804997 0.552209 regulation of nitric oxide biosynthetic process [GO:0045428] 0.583473333 0.548318 RNA splicing factor activity, transesterification mechanism [GO:0031202] 0.58814132 0.541531 regulation of actin polymerization and/or depolymerization [GO:0008064] 0.588229161 0.541404 regulation of actin filament length [GO:0030832] 0.588229161 0.541404 regulation of cellular component size [GO:0032535] 0.588229161 0.541404 nucleoside triphosphate metabolic process [GO:0009141] 0.59021062 0.538531 purine nucleoside triphosphate metabolic process [GO:0009144] 0.59021062 0.538531 ribonucleoside triphosphate metabolic process [GO:0009199] 0.59021062 0.538531 purine ribonucleoside triphosphate metabolic process [GO:0009205] 0.59021062 0.538531 protein amino acid dephosphorylation [GO:0006470] 0.59043514 0.538206 cytokine production [GO:0001816] 0.594126902 0.532865 forebrain cell migration [GO:0021885] 0.595239852 0.531258 telencephalon cell migration [GO:0022029] 0.595239852 0.531258 DNA catabolic process [GO:0006308] 0.59592462 0.53027 drug transporter activity [GO:0015238] 0.596069624 0.530061 histone acetyltransferase activity [GO:0004402] 0.596575387 0.529332 lysine N-acetyltransferase activity [GO:0004468] 0.596575387 0.529332 regulation of DNA recombination [GO:0000018] 0.596941597 0.528804 regulation of nitrogen compound metabolic process [GO:0051171] 0.598151374 0.527061 protein kinase binding [GO:0019901] 0.603313543 0.519641 protein deubiquitination [GO:0016579] 0.603561171 0.519286 glutathione metabolic process [GO:0006749] 0.605471088 0.516549 positive regulation of cellular biosynthetic process [GO:0031328] 0.605865711 0.515984 proteinaceous extracellular matrix [GO:0005578] 0.606363288 0.515272 regulation of binding [GO:0051098] 0.606416235 0.515196 ectoderm development [GO:0007398] 0.609883009 0.51024 protein homooligomerization [GO:0051260] 0.609888974 0.510232 S phase of mitotic cell cycle [GO:0000084] 0.610601502 0.509215 endoplasmic reticulum part [GO:0044432] 0.612284222 0.506816 pattern specification process [GO:0007389] 0.613443095 0.505165 envelope [GO:0031975] 0.613839041 0.504601 lysosome organization and biogenesis [GO:0007040] 0.614141312 0.504171 ATP-dependent helicase activity [GO:0008026] 0.615513079 0.50222 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [GO:0016705] 0.615735202 0.501904 chromosome segregation [GO:0007059] 0.617300565 0.49968 hydrolase activity, acting on acid anhydrides [GO:0016817] 0.617691087 0.499125 nucleolus [GO:0005730] 0.620342817 0.495365 DNA-dependent DNA replication [GO:0006261] 0.620800051 0.494717 heterocycle metabolic process [GO:0046483] 0.621779924 0.493329 inorganic anion transmembrane transporter activity [GO:0015103] 0.625355552 0.488274 regulation of striated muscle development [GO:0016202] 0.625437249 0.488159 regulation of muscle development [GO:0048634] 0.625437249 0.488159 organic acid transmembrane transporter activity [GO:0005342] 0.626087103 0.487242 carboxylic acid transmembrane transporter activity [GO:0046943] 0.626087103 0.487242 muscle cell proliferation [GO:0033002] 0.62792291 0.484652 cytoskeleton-dependent intracellular transport [GO:0030705] 0.628092832 0.484413 negative regulation of metabolic process [GO:0009892] 0.630256513 0.481366 regulation of peptidyl-tyrosine phosphorylation [GO:0050730] 0.630333905 0.481257 response to unfolded protein [GO:0006986] 0.630544032 0.480961 response to protein stimulus [GO:0051789] 0.630544032 0.480961 intercellular junction [GO:0005911] 0.631047115 0.480254 pyruvate metabolic process [GO:0006090] 0.633255917 0.477149 translation [GO:0006412] 0.634278832 0.475713 nucleoside triphosphate biosynthetic process [GO:0009142] 0.634664727 0.475172 purine nucleoside triphosphate biosynthetic process [GO:0009145] 0.634664727 0.475172 ribonucleoside triphosphate biosynthetic process [GO:0009201] 0.634664727 0.475172 purine ribonucleoside triphosphate biosynthetic process [GO:0009206] 0.634664727 0.475172 monooxygenase activity [GO:0004497] 0.635018787 0.474675 ribonucleotide metabolic process [GO:0009259] 0.63955965 0.468315 chromatin [GO:0000785] 0.641487448 0.46562 phosphatidylinositol biosynthetic process [GO:0006661] 0.64149107 0.465615 cytoplasm [GO:0005737] 0.643711479 0.462516 fatty acid alpha-oxidation [GO:0001561] 0.646867608 0.458118 DNA damage response, signal transduction [GO:0042770] 0.647024168 0.4579 regulation of cell proliferation [GO:0042127] 0.647048219 0.457867 BMP signaling pathway [GO:0030509] 0.648450538 0.455916 membrane raft [GO:0045121] 0.648916686 0.455268 microtubule cytoskeleton [GO:0015630] 0.649780977 0.454066 sex differentiation [GO:0007548] 0.650092047 0.453634 positive regulation of multicellular organism growth [GO:0040018] 0.650662867 0.452842 base-excision repair [GO:0006284] 0.651051646 0.452302 cellular response to stimulus [GO:0051716] 0.654151379 0.448003 sulfuric ester hydrolase activity [GO:0008484] 0.655353733 0.446337 reproductive developmental process [GO:0003006] 0.655434258 0.446226 mRNA export from nucleus [GO:0006406] 0.655501912 0.446132 acyl-CoA dehydrogenase activity [GO:0003995] 0.656127431 0.445266 oxidoreductase activity [GO:0016491] 0.656565696 0.44466 cell morphogenesis [GO:0000902] 0.660579071 0.439114 cellular structure morphogenesis [GO:0032989] 0.660579071 0.439114 gonad development [GO:0008406] 0.663670278 0.434851 carboxypeptidase A activity [GO:0004182] 0.664273411 0.434021 phosphoinositide phosphorylation [GO:0046854] 0.66434607 0.433921 fatty acid transport [GO:0015908] 0.665829571 0.431879 long-chain fatty acid transport [GO:0015909] 0.665829571 0.431879 neuron migration [GO:0001764] 0.668090912 0.42877 cytokine activity [GO:0005125] 0.668526011 0.428172 monosaccharide metabolic process [GO:0005996] 0.669411263 0.426956 protein complex [GO:0043234] 0.670534743 0.425414 phosphoprotein phosphatase activity [GO:0004721] 0.672873508 0.422208 regulation of anatomical structure morphogenesis [GO:0022603] 0.67723326 0.416242 endothelial cell differentiation [GO:0045446] 0.678249826 0.414853 regulation of transferase activity [GO:0051338] 0.679258698 0.413475 magnesium ion binding [GO:0000287] 0.679984775 0.412484 cysteine-type peptidase activity [GO:0008234] 0.680325401 0.412019 cell junction assembly and maintenance [GO:0034330] 0.681116928 0.410939 nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity [GO:0015932] 0.683434228 0.407781 water homeostasis [GO:0030104] 0.68375252 0.407348 positive regulation of protein kinase activity [GO:0045860] 0.683770892 0.407323 amino acid derivative biosynthetic process [GO:0042398] 0.68470444 0.406052 neuroblast proliferation [GO:0007405] 0.685401188 0.405104 regulation of growth [GO:0040008] 0.685574315 0.404868 ubiquitin thiolesterase activity [GO:0004221] 0.687550746 0.402181 transcription repressor activity [GO:0016564] 0.688657333 0.400678 positive regulation of cell proliferation [GO:0008284] 0.688658492 0.400676 cholesterol binding [GO:0015485] 0.688749914 0.400552 development of primary sexual characteristics [GO:0045137] 0.69021218 0.398567 protein kinase cascade [GO:0007243] 0.691411889 0.39694 respiratory gaseous exchange [GO:0007585] 0.692500697 0.395464 chromatin remodeling [GO:0006338] 0.696884817 0.389529 macromolecular complex assembly [GO:0065003] 0.698427448 0.387444 placenta development [GO:0001890] 0.698768146 0.386984 positive regulation of epithelial cell proliferation [GO:0050679] 0.699202801 0.386397 regulation of cell shape [GO:0008360] 0.703595856 0.380471 voltage-gated cation channel activity [GO:0022843] 0.704670285 0.379024 branching morphogenesis of a tube [GO:0048754] 0.705167994 0.378354 GTP binding [GO:0005525] 0.70631943 0.376804 nucleoside monophosphate metabolic process [GO:0009123] 0.706584968 0.376447 nucleoside monophosphate biosynthetic process [GO:0009124] 0.706584968 0.376447 ribonucleoside monophosphate biosynthetic process [GO:0009156] 0.706584968 0.376447 ribonucleoside monophosphate metabolic process [GO:0009161] 0.706584968 0.376447 extracellular matrix [GO:0031012] 0.707013668 0.37587 G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [GO:0007200] 0.708196327 0.37428 regulation of axonogenesis [GO:0050770] 0.708786291 0.373487 cytoplasmic part [GO:0044444] 0.713928588 0.366585 eukaryotic translation initiation factor 3 complex [GO:0005852] 0.71395619 0.366548 catalytic activity [GO:0003824] 0.714165552 0.366267 porphyrin biosynthetic process [GO:0006779] 0.718777575 0.360093 heme biosynthetic process [GO:0006783] 0.718777575 0.360093 tetrapyrrole biosynthetic process [GO:0033014] 0.718777575 0.360093 protein complex assembly [GO:0006461] 0.720753749 0.357452 positive regulation of developmental process [GO:0051094] 0.723628525 0.353614 photoreceptor outer segment [GO:0001750] 0.724182019 0.352875 apoptotic mitochondrial changes [GO:0008637] 0.725172703 0.351554 transferase activity, transferring phosphorus-containing groups [GO:0016772] 0.726828181 0.349348 response to peptide hormone stimulus [GO:0043434] 0.727895327 0.347927 coenzyme metabolic process [GO:0006732] 0.728689724 0.346869 organellar ribosome [GO:0000313] 0.728907684 0.346579 mitochondrial ribosome [GO:0005761] 0.728907684 0.346579 regulation of action potential in neuron [GO:0019228] 0.732320019 0.342041 protein transmembrane transporter activity [GO:0008320] 0.732725877 0.341502 integral to membrane [GO:0016021] 0.733628039 0.340303 positive regulation of cellular process [GO:0048522] 0.734167417 0.339587 regulation of biosynthetic process [GO:0009889] 0.736254053 0.336818 embryonic morphogenesis [GO:0048598] 0.742788154 0.328163 endonuclease activity [GO:0004519] 0.7442894 0.326178 nucleoside metabolic process [GO:0009116] 0.748047291 0.321215 mitochondrial intermembrane space [GO:0005758] 0.749076715 0.319857 organelle envelope lumen [GO:0031970] 0.749076715 0.319857 alcohol biosynthetic process [GO:0046165] 0.749285281 0.319582 monosaccharide biosynthetic process [GO:0046364] 0.749285281 0.319582 transferase activity, transferring pentosyl groups [GO:0016763] 0.74966731 0.319078 neural crest cell migration [GO:0001755] 0.751435771 0.316747 steroid biosynthetic process [GO:0006694] 0.752585641 0.315232 transcription factor activity [GO:0003700] 0.752907558 0.314808 regulation of cell growth [GO:0001558] 0.7534515 0.314092 response to hormone stimulus [GO:0009725] 0.754092479 0.313248 cell division [GO:0051301] 0.754420592 0.312816 nuclear chromatin [GO:0000790] 0.757004878 0.309416 intrinsic to membrane [GO:0031224] 0.757155038 0.309219 nucleoside kinase activity [GO:0019206] 0.757186645 0.309177 acetylgalactosaminyltransferase activity [GO:0008376] 0.757538873 0.308714 mitochondrial part [GO:0044429] 0.75811129 0.307962 hexose catabolic process [GO:0019320] 0.759521581 0.306109 alcohol catabolic process [GO:0046164] 0.759521581 0.306109 monosaccharide catabolic process [GO:0046365] 0.759521581 0.306109 DNA metabolic process [GO:0006259] 0.761746951 0.303188 negative regulation of cellular metabolic process [GO:0031324] 0.763092646 0.301422 localization within membrane [GO:0051668] 0.763112918 0.301396 DNA helicase activity [GO:0003678] 0.765718457 0.29798 negative regulation of neuron apoptosis [GO:0043524] 0.766989665 0.296315 transcription factor complex [GO:0005667] 0.767480197 0.295673 structural constituent of ribosome [GO:0003735] 0.768331457 0.294558 maintenance of protein location in cell [GO:0032507] 0.769240373 0.293369 maintenance of protein location [GO:0045185] 0.769240373 0.293369 maintenance of location in cell [GO:0051651] 0.769240373 0.293369 membrane lipid biosynthetic process [GO:0046467] 0.772870881 0.288622 positive regulation of kinase activity [GO:0033674] 0.773057654 0.288378 RNA 3'-end processing [GO:0031123] 0.773067061 0.288365 mRNA 3'-end processing [GO:0031124] 0.773067061 0.288365 protein targeting to membrane [GO:0006612] 0.774129118 0.286978 hydro-lyase activity [GO:0016836] 0.774740846 0.286179 Notch receptor processing [GO:0007220] 0.775924034 0.284635 protein maturation via proteolysis [GO:0051605] 0.775924034 0.284635 negative regulation of protein metabolic process [GO:0051248] 0.777219043 0.282945 ubiquitin-specific protease activity [GO:0004843] 0.777529686 0.28254 small conjugating protein-specific protease activity [GO:0019783] 0.777529686 0.28254 intracellular ligand-gated ion channel activity [GO:0005217] 0.780514451 0.278649 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [GO:0016620] 0.781276872 0.277655 mitochondrial inner membrane [GO:0005743] 0.783429227 0.274853 reproductive process [GO:0022414] 0.786946822 0.270277 deacetylase activity [GO:0019213] 0.78947476 0.266993 clathrin coat of coated pit [GO:0030132] 0.789948598 0.266377 regulation of protein amino acid phosphorylation [GO:0001932] 0.790200983 0.26605 integral to Golgi membrane [GO:0030173] 0.790401863 0.265789 intrinsic to Golgi membrane [GO:0031228] 0.793270587 0.262066 low-density lipoprotein binding [GO:0030169] 0.793869452 0.261289 ion channel inhibitor activity [GO:0008200] 0.794331074 0.260691 channel inhibitor activity [GO:0016248] 0.794331074 0.260691 ruffle [GO:0001726] 0.794440487 0.260549 negative regulation of translation [GO:0017148] 0.798026628 0.255902 hemopoiesis [GO:0030097] 0.799516745 0.253973 glutamine metabolic process [GO:0006541] 0.800732236 0.2524 vitamin A metabolic process [GO:0006776] 0.801765544 0.251063 protein autoprocessing [GO:0016540] 0.801884391 0.250909 protein amino acid autophosphorylation [GO:0046777] 0.801884391 0.250909 DNA fragmentation during apoptosis [GO:0006309] 0.801906452 0.250881 cell structure disassembly during apoptosis [GO:0006921] 0.801906452 0.250881 cellular component disassembly [GO:0022411] 0.801906452 0.250881 apoptotic nuclear changes [GO:0030262] 0.801906452 0.250881 N-terminal protein amino acid modification [GO:0031365] 0.803578431 0.248719 DNA recombination [GO:0006310] 0.803996493 0.248178 protein-RNA complex assembly [GO:0022618] 0.804803441 0.247135 negative regulation of apoptosis [GO:0043066] 0.805862959 0.245767 positive regulation of catabolic process [GO:0009896] 0.806358072 0.245127 biogenic amine biosynthetic process [GO:0042401] 0.808537948 0.242313 cysteine-type endopeptidase activity [GO:0004197] 0.808717557 0.242081 ribosome [GO:0005840] 0.809574087 0.240976 regulation of multicellular organism growth [GO:0040014] 0.810696495 0.239528 non-membrane spanning protein tyrosine kinase activity [GO:0004715] 0.811071548 0.239044 sugar binding [GO:0005529] 0.813476718 0.235943 nucleobase, nucleoside, nucleotide kinase activity [GO:0019205] 0.813853971 0.235457 protein oligomerization [GO:0051259] 0.814217002 0.234989 vesicle membrane [GO:0012506] 0.814933316 0.234067 phosphate transport [GO:0006817] 0.816284082 0.232327 nuclease activity [GO:0004518] 0.81775627 0.230432 bone mineralization [GO:0030282] 0.818587588 0.229362 regulation of bone mineralization [GO:0030500] 0.818587588 0.229362 positive regulation of bone mineralization [GO:0030501] 0.818587588 0.229362 regulation of neurogenesis [GO:0050767] 0.820535381 0.226856 amine transport [GO:0015837] 0.820961511 0.226308 positive regulation of hydrolase activity [GO:0051345] 0.822351747 0.224521 positive regulation of MAPKKK cascade [GO:0043410] 0.823557444 0.222972 unfolded protein response [GO:0030968] 0.824483903 0.221782 negative regulation of programmed cell death [GO:0043069] 0.825905209 0.219956 hexose metabolic process [GO:0019318] 0.830605267 0.213925 glycerophospholipid metabolic process [GO:0006650] 0.830747493 0.213743 mannose binding [GO:0005537] 0.831014052 0.213401 regulation of synapse structure and activity [GO:0050803] 0.831014052 0.213401 monosaccharide transmembrane transporter activity [GO:0015145] 0.832414906 0.211605 hexose transmembrane transporter activity [GO:0015149] 0.832414906 0.211605 coated pit [GO:0005905] 0.832838827 0.211062 nuclear organization and biogenesis [GO:0006997] 0.836264959 0.206673 regulation of inflammatory response [GO:0050727] 0.836451701 0.206434 transcription cofactor activity [GO:0003712] 0.837549464 0.205029 pentose-phosphate shunt [GO:0006098] 0.837555891 0.205021 NADPH regeneration [GO:0006740] 0.837555891 0.205021 macromolecular complex [GO:0032991] 0.840404115 0.201377 trans-Golgi network transport vesicle membrane [GO:0012510] 0.840636568 0.201079 clathrin coat of trans-Golgi network vesicle [GO:0030130] 0.840636568 0.201079 cation-transporting ATPase activity [GO:0019829] 0.841449963 0.200039 transcription regulator activity [GO:0030528] 0.844476304 0.196171 condensed chromosome [GO:0000793] 0.846514009 0.193568 cellular monovalent inorganic cation homeostasis [GO:0030004] 0.847951259 0.191733 morphogenesis of an epithelium [GO:0002009] 0.848251356 0.19135 actin filament polymerization [GO:0030041] 0.850698426 0.188227 regulation of DNA replication [GO:0006275] 0.85340158 0.18478 endocrine system development [GO:0035270] 0.855050342 0.182678 isoprenoid biosynthetic process [GO:0008299] 0.855760906 0.181773 protein amino acid O-linked glycosylation [GO:0006493] 0.860475882 0.175768 regulation of monooxygenase activity [GO:0032768] 0.863360694 0.172098 regulation of nitric-oxide synthase activity [GO:0050999] 0.863360694 0.172098 chromatin assembly or disassembly [GO:0006333] 0.864976861 0.170042 membrane docking [GO:0022406] 0.865294118 0.169639 protein import into nucleus [GO:0006606] 0.866356794 0.168288 nuclear import [GO:0051170] 0.866356794 0.168288 regulation of mitotic cell cycle [GO:0007346] 0.866396215 0.168238 response to reactive oxygen species [GO:0000302] 0.867010716 0.167457 ARF guanyl-nucleotide exchange factor activity [GO:0005086] 0.868069026 0.166112 nucleotide kinase activity [GO:0019201] 0.86854012 0.165513 nuclear chromosome [GO:0000228] 0.872112604 0.160976 serine-type endopeptidase activity [GO:0004252] 0.872401332 0.160609 epidermal growth factor receptor signaling pathway [GO:0007173] 0.882041433 0.148382 actin binding [GO:0003779] 0.883160944 0.146963 endoplasmic reticulum membrane [GO:0005789] 0.883215949 0.146894 regulation of transcription factor activity [GO:0051090] 0.885123629 0.144477 phosphoinositide 3-kinase complex [GO:0005942] 0.888211162 0.140568 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [GO:0016706] 0.888333858 0.140413 amine metabolic process [GO:0009308] 0.888369742 0.140367 transmembrane receptor protein serine/threonine kinase activity [GO:0004675] 0.888634243 0.140033 transforming growth factor beta receptor activity [GO:0005024] 0.888634243 0.140033 ureteric bud development [GO:0001657] 0.891505505 0.136399 cell aging [GO:0007569] 0.893290197 0.134142 B cell activation [GO:0042113] 0.89338478 0.134023 stereocilium [GO:0032420] 0.894991031 0.131991 stereocilium bundle [GO:0032421] 0.894991031 0.131991 response to stress [GO:0006950] 0.895554596 0.131279 negative regulation of cellular protein metabolic process [GO:0032269] 0.897118522 0.129302 cell growth [GO:0016049] 0.897315832 0.129053 guanyl nucleotide binding [GO:0019001] 0.900985283 0.124417 guanyl ribonucleotide binding [GO:0032561] 0.900985283 0.124417 negative regulation of signal transduction [GO:0009968] 0.901023728 0.124368 protein maturation [GO:0051604] 0.902612988 0.122361 transcription from RNA polymerase II promoter [GO:0006366] 0.903422726 0.121339 mRNA splice site selection [GO:0006376] 0.903490394 0.121253 amino acid and derivative metabolic process [GO:0006519] 0.906057559 0.118013 regulation of fatty acid oxidation [GO:0046320] 0.906395395 0.117586 small nucleolar ribonucleoprotein complex [GO:0005732] 0.906430806 0.117542 ovulation cycle process [GO:0022602] 0.906476015 0.117485 ovulation cycle [GO:0042698] 0.906476015 0.117485 axon cargo transport [GO:0008088] 0.910782315 0.112052 aging [GO:0007568] 0.91122441 0.111494 actin cytoskeleton [GO:0015629] 0.912995708 0.109261 basolateral plasma membrane [GO:0016323] 0.91351321 0.108608 post-Golgi vesicle-mediated transport [GO:0006892] 0.913963051 0.108041 lipoprotein binding [GO:0008034] 0.914072844 0.107903 insulin receptor binding [GO:0005158] 0.914148085 0.107808 nitrogen compound metabolic process [GO:0006807] 0.916133577 0.105305 phosphoinositide biosynthetic process [GO:0046489] 0.916172766 0.105256 DNA damage response, signal transduction resulting in induction of apoptosis [GO:0008630] 0.918861402 0.101868 nonmotile primary cilium [GO:0031513] 0.920206354 0.100174 beta-catenin binding [GO:0008013] 0.920608672 0.099667 apical junction complex [GO:0043296] 0.921055887 0.099104 chromosome [GO:0005694] 0.928911981 0.089214 hemopoietic or lymphoid organ development [GO:0048534] 0.929152541 0.088911 hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553] 0.933320408 0.083668 oxidoreductase activity, acting on sulfur group of donors [GO:0016667] 0.933636968 0.08327 oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [GO:0016668] 0.933636968 0.08327 regulation of peptidase activity [GO:0052547] 0.933853901 0.082997 tissue development [GO:0009888] 0.936963856 0.079086 O-acyltransferase activity [GO:0008374] 0.939171696 0.076311 cellular response to stress [GO:0033554] 0.941731127 0.073094 germ cell development [GO:0007281] 0.945513789 0.068341 memory [GO:0007613] 0.946844868 0.066669 regulation of defense response [GO:0031347] 0.94713698 0.066303 regulation of phosphate metabolic process [GO:0019220] 0.949540466 0.063284 regulation of phosphorus metabolic process [GO:0051174] 0.949540466 0.063284 carbohydrate kinase activity [GO:0019200] 0.954947492 0.056495 threonine endopeptidase activity [GO:0004298] 0.955366363 0.055969 proteasome core complex [GO:0005839] 0.955366363 0.055969 regulation of DNA binding [GO:0051101] 0.956327373 0.054763 cellular protein complex assembly [GO:0043623] 0.956849427 0.054108 regulation of cellular biosynthetic process [GO:0031326] 0.957241699 0.053615 vesicle docking during exocytosis [GO:0006904] 0.957575487 0.053196 vesicle docking [GO:0048278] 0.957575487 0.053196 cysteine metabolic process [GO:0006534] 0.958227845 0.052378 embryonic epithelial tube formation [GO:0001838] 0.960078589 0.050055 morphogenesis of embryonic epithelium [GO:0016331] 0.960078589 0.050055 transcription factor binding [GO:0008134] 0.960108948 0.050017 hormone binding [GO:0042562] 0.960810174 0.049137 nucleotide-excision repair, DNA damage removal [GO:0000718] 0.963927544 0.045226 cell projection part [GO:0044463] 0.964399163 0.044634 regulation of JNK activity [GO:0043506] 0.964668093 0.044296 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [GO:0016646] 0.968604117 0.039359 sister chromatid cohesion [GO:0007062] 0.968724274 0.039208 fat-soluble vitamin metabolic process [GO:0006775] 0.968761591 0.039162 sulfur metabolic process [GO:0006790] 0.972870399 0.034008 regulation of protein transport [GO:0051223] 0.975305835 0.030954 gluconeogenesis [GO:0006094] 0.975981835 0.030107 hexose biosynthetic process [GO:0019319] 0.975981835 0.030107 cell death [GO:0008219] 0.978513352 0.026933 death [GO:0016265] 0.978513352 0.026933 lysosomal membrane [GO:0005765] 0.979096176 0.026202 endomembrane system [GO:0012505] 0.980124258 0.024913 response to inorganic substance [GO:0010035] 0.980134223 0.024901 response to metal ion [GO:0010038] 0.980134223 0.024901 protein amino acid acylation [GO:0043543] 0.980721418 0.024164 clathrin vesicle coat [GO:0030125] 0.980738253 0.024143 clathrin coated vesicle membrane [GO:0030665] 0.980738253 0.024143 DNA replication [GO:0006260] 0.981535826 0.023143 nuclear envelope-endoplasmic reticulum network [GO:0042175] 0.982134695 0.022393 nuclear speck [GO:0016607] 0.983967266 0.020095 fibroblast proliferation [GO:0048144] 0.988677853 0.014191 regulation of fibroblast proliferation [GO:0048145] 0.988677853 0.014191 positive regulation of fibroblast proliferation [GO:0048146] 0.988677853 0.014191 intracellular transport [GO:0046907] 0.991336091 0.010859 double-stranded DNA binding [GO:0003690] 0.99376443 0.007815 embryonic development ending in birth or egg hatching [GO:0009792] 0.994573488 0.006801 chordate embryonic development [GO:0043009] 0.994573488 0.006801 protein processing [GO:0016485] 0.995398184 0.005768 insulin-like growth factor receptor signaling pathway [GO:0048009] 0.99645145 0.004447 active transmembrane transporter activity [GO:0022804] 0.996767701 0.004051 lysosomal transport [GO:0007041] 0.999804947 0.000244 endoribonuclease activity [GO:0004521] 0.997464319 -0.003178 di-, tri-valent inorganic cation transmembrane transporter activity [GO:0015082] 0.996684113 -0.004156 cofactor biosynthetic process [GO:0051188] 0.99646589 -0.004429 transferase activity, transferring sulfur-containing groups [GO:0016782] 0.995513739 -0.005623 regulation of cellular pH [GO:0030641] 0.995513739 -0.005623 regulation of intracellular pH [GO:0051453] 0.995513739 -0.005623 trans-Golgi network transport vesicle [GO:0030140] 0.995437589 -0.005718 sulfur amino acid biosynthetic process [GO:0000097] 0.994343519 -0.007089 histone deacetylation [GO:0016575] 0.994029876 -0.007483 response to extracellular stimulus [GO:0009991] 0.9937857 -0.007789 inflammatory response [GO:0006954] 0.989381669 -0.013308 oxidoreductase activity, acting on NADH or NADPH [GO:0016651] 0.987768556 -0.01533 lipid phosphorylation [GO:0046834] 0.986454526 -0.016978 mechanoreceptor differentiation [GO:0042490] 0.984201762 -0.019801 proteoglycan metabolic process [GO:0006029] 0.983978633 -0.020081 hormone-mediated signaling [GO:0009755] 0.982842898 -0.021505 DNA-directed RNA polymerase activity [GO:0003899] 0.982827212 -0.021525 RNA polymerase activity [GO:0034062] 0.982827212 -0.021525 regulation of cell size [GO:0008361] 0.98190901 -0.022676 palmitoyltransferase activity [GO:0016409] 0.981135991 -0.023645 phosphoric diester hydrolase activity [GO:0008081] 0.980617788 -0.024294 regulation of intracellular transport [GO:0032386] 0.979172695 -0.026106 protein kinase regulator activity [GO:0019887] 0.977774161 -0.02786 positive regulation of transferase activity [GO:0051347] 0.977248713 -0.028518 cytoskeleton organization and biogenesis [GO:0007010] 0.977160629 -0.028629 ribonucleoprotein complex [GO:0030529] 0.976669537 -0.029245 caspase activation [GO:0006919] 0.973475167 -0.03325 mitochondrial membrane [GO:0031966] 0.971130705 -0.03619 negative regulation of cell differentiation [GO:0045596] 0.970440496 -0.037056 regulation of protein modification process [GO:0031399] 0.970106741 -0.037474 intracellular membrane-bounded organelle [GO:0043231] 0.969615198 -0.038091 Golgi transport complex [GO:0017119] 0.968177187 -0.039895 nucleoside diphosphate kinase activity [GO:0004550] 0.967769802 -0.040406 GTP biosynthetic process [GO:0006183] 0.967769802 -0.040406 UTP biosynthetic process [GO:0006228] 0.967769802 -0.040406 CTP biosynthetic process [GO:0006241] 0.967769802 -0.040406 pyrimidine nucleoside triphosphate metabolic process [GO:0009147] 0.967769802 -0.040406 pyrimidine ribonucleoside triphosphate metabolic process [GO:0009208] 0.967769802 -0.040406 pyrimidine ribonucleoside triphosphate biosynthetic process [GO:0009209] 0.967769802 -0.040406 CTP metabolic process [GO:0046036] 0.967769802 -0.040406 GTP metabolic process [GO:0046039] 0.967769802 -0.040406 UTP metabolic process [GO:0046051] 0.967769802 -0.040406 mismatch repair [GO:0006298] 0.964430636 -0.044594 maintenance of fidelity during DNA-dependent DNA replication [GO:0045005] 0.964430636 -0.044594 regulation of JAK-STAT cascade [GO:0046425] 0.964190954 -0.044895 T cell differentiation in the thymus [GO:0033077] 0.961774403 -0.047927 diencephalon development [GO:0021536] 0.960612827 -0.049385 pituitary gland development [GO:0021983] 0.960612827 -0.049385 aminoacyl-tRNA ligase activity [GO:0004812] 0.960138282 -0.04998 ligase activity, forming carbon-oxygen bonds [GO:0016875] 0.960138282 -0.04998 ligase activity, forming aminoacyl-tRNA and related compounds [GO:0016876] 0.960138282 -0.04998 mitochondrial outer membrane [GO:0005741] 0.959287054 -0.051048 synaptonemal complex [GO:0000795] 0.957750893 -0.052976 positive regulation of caspase activity [GO:0043280] 0.950794358 -0.061709 regulation of caspase activity [GO:0043281] 0.950794358 -0.061709 regulation of endopeptidase activity [GO:0052548] 0.950794358 -0.061709 heterochromatin [GO:0000792] 0.950476282 -0.062109 iron ion transport [GO:0006826] 0.94869187 -0.06435 circadian rhythm [GO:0007623] 0.94869187 -0.06435 hydrolase activity, acting on glycosyl bonds [GO:0016798] 0.948655943 -0.064395 vacuolar membrane [GO:0005774] 0.947527102 -0.065813 regulation of myeloid cell differentiation [GO:0045637] 0.947272466 -0.066132 protein amino acid deacetylation [GO:0006476] 0.946790109 -0.066738 mRNA binding [GO:0003729] 0.945160591 -0.068785 transcription corepressor activity [GO:0003714] 0.944727626 -0.069329 microtubule-based process [GO:0007017] 0.942143883 -0.072576 establishment and/or maintenance of cell polarity [GO:0007163] 0.941754036 -0.073065 response to heat [GO:0009408] 0.94027233 -0.074928 membrane-bounded organelle [GO:0043227] 0.93937718 -0.076053 flagellum biogenesis [GO:0009296] 0.937258513 -0.078716 flagellum organization and biogenesis [GO:0043064] 0.937258513 -0.078716 kidney development [GO:0001822] 0.935339115 -0.081129 pallium development [GO:0021543] 0.934878113 -0.081709 cerebral cortex development [GO:0021987] 0.934878113 -0.081709 multicellular organism growth [GO:0035264] 0.933100571 -0.083944 tRNA aminoacylation for protein translation [GO:0006418] 0.932857642 -0.08425 amino acid activation [GO:0043038] 0.932857642 -0.08425 tRNA aminoacylation [GO:0043039] 0.932857642 -0.08425 negative regulation of Wnt receptor signaling pathway [GO:0030178] 0.932785434 -0.084341 regulation of translational initiation [GO:0006446] 0.932715772 -0.084428 intracellular lipid transport [GO:0032365] 0.929167566 -0.088892 DNA alkylation [GO:0006305] 0.927734526 -0.090696 DNA methylation [GO:0006306] 0.927734526 -0.090696 skeletal morphogenesis [GO:0048705] 0.922148053 -0.097728 forebrain development [GO:0030900] 0.920485305 -0.099822 symbiosis, encompassing mutualism through parasitism [GO:0044403] 0.920022185 -0.100406 FMN binding [GO:0010181] 0.919968008 -0.100474 activation of protein kinase activity [GO:0032147] 0.918420229 -0.102424 immune response-activating cell surface receptor signaling pathway [GO:0002429] 0.917259414 -0.103887 immune response-activating signal transduction [GO:0002757] 0.917259414 -0.103887 immune response-regulating signal transduction [GO:0002764] 0.917259414 -0.103887 immune response-regulating cell surface receptor signaling pathway [GO:0002768] 0.917259414 -0.103887 antigen receptor-mediated signaling pathway [GO:0050851] 0.917259414 -0.103887 gland development [GO:0048732] 0.916304707 -0.10509 protein tyrosine phosphatase activity [GO:0004725] 0.915923188 -0.10557 cell projection membrane [GO:0031253] 0.913483236 -0.108646 cell cycle process [GO:0022402] 0.910728577 -0.11212 coated vesicle [GO:0030135] 0.910121013 -0.112886 potassium channel activity [GO:0005267] 0.907793655 -0.115822 primary active transmembrane transporter activity [GO:0015399] 0.907593592 -0.116074 P-P-bond-hydrolysis-driven transmembrane transporter activity [GO:0015405] 0.907593592 -0.116074 glycerophospholipid biosynthetic process [GO:0046474] 0.907002528 -0.11682 urea cycle intermediate metabolic process [GO:0000051] 0.905399864 -0.118843 ATPase activity, coupled to transmembrane movement of substances [GO:0042626] 0.904142719 -0.12043 chloride transport [GO:0006821] 0.902405732 -0.122623 oligodendrocyte development [GO:0014003] 0.901764887 -0.123432 glial cell development [GO:0021782] 0.901764887 -0.123432 oligodendrocyte differentiation [GO:0048709] 0.901764887 -0.123432 inner ear morphogenesis [GO:0042472] 0.900738577 -0.124728 homeostasis of number of cells [GO:0048872] 0.900113482 -0.125518 peroxidase activity [GO:0004601] 0.899722879 -0.126011 oxidoreductase activity, acting on peroxide as acceptor [GO:0016684] 0.899722879 -0.126011 regulation of phosphorylation [GO:0042325] 0.898466458 -0.127599 regulation of response to biotic stimulus [GO:0002831] 0.895701281 -0.131094 regulation of defense response to virus [GO:0050688] 0.895701281 -0.131094 regulation of defense response to virus by virus [GO:0050690] 0.895701281 -0.131094 microtubule-based movement [GO:0007018] 0.894892296 -0.132116 phosphoric ester hydrolase activity [GO:0042578] 0.894160282 -0.133042 protein-chromophore linkage [GO:0018298] 0.892866774 -0.134678 regulation of homeostatic process [GO:0032844] 0.890750119 -0.137355 hormone biosynthetic process [GO:0042446] 0.889903675 -0.138426 phosphoric monoester hydrolase activity [GO:0016791] 0.888667969 -0.13999 inner ear development [GO:0048839] 0.886340145 -0.142937 multicellular organism reproduction [GO:0032504] 0.884913176 -0.144744 reproductive process in a multicellular organism [GO:0048609] 0.884913176 -0.144744 intramolecular transferase activity [GO:0016866] 0.883136713 -0.146994 histone deacetylase activity [GO:0004407] 0.882647891 -0.147613 protein deacetylase activity [GO:0033558] 0.882647891 -0.147613 cell cycle phase [GO:0022403] 0.880020581 -0.150943 iron ion binding [GO:0005506] 0.877870581 -0.153669 actin filament binding [GO:0051015] 0.877486619 -0.154156 response to nutrient levels [GO:0031667] 0.87429717 -0.158203 ARF protein signal transduction [GO:0032011] 0.873561546 -0.159136 regulation of ARF protein signal transduction [GO:0032012] 0.873561546 -0.159136 positive regulation of angiogenesis [GO:0045766] 0.872782043 -0.160126 MAPKKK cascade [GO:0000165] 0.871705892 -0.161492 glutamine family amino acid catabolic process [GO:0009065] 0.868785803 -0.165201 protein amino acid N-linked glycosylation [GO:0006487] 0.86649302 -0.168115 skeletal development [GO:0001501] 0.865603973 -0.169245 G1 phase [GO:0051318] 0.862629847 -0.173027 regionalization [GO:0003002] 0.861037492 -0.175054 endoribonuclease activity, producing 5'-phosphomonoesters [GO:0016891] 0.859943242 -0.176446 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [GO:0016893] 0.859943242 -0.176446 inorganic anion transport [GO:0015698] 0.85889333 -0.177783 nicotinamide metabolic process [GO:0006769] 0.857787816 -0.179191 pyridine nucleotide metabolic process [GO:0019362] 0.857787816 -0.179191 late endosome membrane [GO:0031902] 0.856262647 -0.181134 actin filament [GO:0005884] 0.855322249 -0.182332 oxidoreductase activity, acting on the aldehyde or oxo group of donors [GO:0016903] 0.855101398 -0.182613 ovarian follicle development [GO:0001541] 0.853567054 -0.184569 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [GO:0045934] 0.851896149 -0.1867 nucleus [GO:0005634] 0.85181932 -0.186798 phosphotransferase activity, phosphate group as acceptor [GO:0016776] 0.850623368 -0.188323 positive regulation of phosphorus metabolic process [GO:0010562] 0.850494372 -0.188488 positive regulation of phosphorylation [GO:0042327] 0.850494372 -0.188488 positive regulation of phosphate metabolic process [GO:0045937] 0.850494372 -0.188488 organelle inner membrane [GO:0019866] 0.85046414 -0.188526 immune system development [GO:0002520] 0.850093623 -0.188999 NAD+ ADP-ribosyltransferase activity [GO:0003950] 0.848005063 -0.191664 auditory receptor cell differentiation [GO:0042491] 0.84645201 -0.193647 late endosome [GO:0005770] 0.844153562 -0.196583 sugar:hydrogen symporter activity [GO:0005351] 0.842437977 -0.198776 cation:sugar symporter activity [GO:0005402] 0.842437977 -0.198776 solute:hydrogen symporter activity [GO:0015295] 0.842437977 -0.198776 glycoprotein catabolic process [GO:0006516] 0.836869981 -0.205899 ARF GTPase activator activity [GO:0008060] 0.836153106 -0.206817 regulation of ARF GTPase activity [GO:0032312] 0.836153106 -0.206817 positive regulation of myeloid cell differentiation [GO:0045639] 0.834817995 -0.208526 establishment of localization in cell [GO:0051649] 0.831974616 -0.21217 regulation of intracellular protein transport [GO:0033157] 0.831779959 -0.212419 nucleotide binding [GO:0000166] 0.830665611 -0.213848 glycerol metabolic process [GO:0006071] 0.830621498 -0.213905 transition metal ion transmembrane transporter activity [GO:0046915] 0.83054722 -0.214 regulation of oxidoreductase activity [GO:0051341] 0.827678666 -0.21768 apoptosis [GO:0006915] 0.823069447 -0.223599 embryonic limb morphogenesis [GO:0030326] 0.820451719 -0.226964 embryonic appendage morphogenesis [GO:0035113] 0.820451719 -0.226964 enzyme binding [GO:0019899] 0.818959727 -0.228883 carbon-oxygen lyase activity [GO:0016835] 0.816501001 -0.232048 regulation of molecular function [GO:0065009] 0.815375978 -0.233496 GPI anchor metabolic process [GO:0006505] 0.814968504 -0.234021 GPI anchor biosynthetic process [GO:0006506] 0.814968504 -0.234021 Notch signaling pathway [GO:0007219] 0.810770165 -0.239433 coenzyme biosynthetic process [GO:0009108] 0.809158214 -0.241512 positive regulation of DNA replication [GO:0045740] 0.807293479 -0.243919 positive regulation of DNA metabolic process [GO:0051054] 0.807293479 -0.243919 protein secretion [GO:0009306] 0.804933957 -0.246967 regulation of macromolecule biosynthetic process [GO:0010556] 0.803085334 -0.249356 negative regulation of growth [GO:0045926] 0.80248611 -0.250131 carbohydrate transmembrane transporter activity [GO:0015144] 0.800977795 -0.252082 sugar transmembrane transporter activity [GO:0051119] 0.800977795 -0.252082 vitamin D receptor binding [GO:0042809] 0.798488892 -0.255303 peroxisome [GO:0005777] 0.797562475 -0.256503 microbody [GO:0042579] 0.797562475 -0.256503 tight junction [GO:0005923] 0.796933722 -0.257317 B cell differentiation [GO:0030183] 0.793502691 -0.261765 NF-kappaB binding [GO:0051059] 0.792330201 -0.263286 phospholipid biosynthetic process [GO:0008654] 0.789242508 -0.267294 interphase [GO:0051325] 0.784872731 -0.272975 interaction with host [GO:0051701] 0.784652384 -0.273261 transport vesicle [GO:0030133] 0.783932922 -0.274197 transferase activity [GO:0016740] 0.782836598 -0.275624 meiosis [GO:0007126] 0.782063418 -0.276631 meiotic cell cycle [GO:0051321] 0.782063418 -0.276631 M phase of meiotic cell cycle [GO:0051327] 0.782063418 -0.276631 cartilage condensation [GO:0001502] 0.781276872 -0.277655 protein amino acid glycosylation [GO:0006486] 0.780291753 -0.278939 biopolymer glycosylation [GO:0043413] 0.780291753 -0.278939 intracellular signaling cascade [GO:0007242] 0.778618419 -0.28112 condensed nuclear chromosome [GO:0000794] 0.777707388 -0.282308 oxidoreductase activity, acting on the CH-NH group of donors [GO:0016645] 0.777495347 -0.282585 programmed cell death [GO:0012501] 0.775647675 -0.284995 microtubule [GO:0005874] 0.775219688 -0.285554 growth [GO:0040007] 0.772709819 -0.288832 hydrolase activity, hydrolyzing N-glycosyl compounds [GO:0016799] 0.772657228 -0.288901 DNA N-glycosylase activity [GO:0019104] 0.772657228 -0.288901 female gamete generation [GO:0007292] 0.771868127 -0.289932 regulation of erythrocyte differentiation [GO:0045646] 0.771306996 -0.290666 retrograde axon cargo transport [GO:0008090] 0.770883606 -0.291219 protein import [GO:0017038] 0.770537407 -0.291672 SH2 domain binding [GO:0042169] 0.769437815 -0.29311 FAD binding [GO:0050660] 0.768065581 -0.294906 phosphotransferase activity, for other substituted phosphate groups [GO:0016780] 0.764882565 -0.299075 polyol metabolic process [GO:0019751] 0.764665487 -0.29936 cellular localization [GO:0051641] 0.762057368 -0.30278 histone deacetylase complex [GO:0000118] 0.759794649 -0.30575 transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] 0.759654396 -0.305935 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances [GO:0016820] 0.757513848 -0.308747 metanephros development [GO:0001656] 0.757276102 -0.30906 regulation of I-kappaB kinase/NF-kappaB cascade [GO:0043122] 0.75621985 -0.310449 cis-Golgi network [GO:0005801] 0.754918521 -0.312161 organelle membrane [GO:0031090] 0.754749634 -0.312383 protein-DNA complex assembly [GO:0065004] 0.754482982 -0.312734 ATPase activity, coupled to movement of substances [GO:0043492] 0.752720369 -0.315054 excretion [GO:0007588] 0.752506275 -0.315336 response to DNA damage stimulus [GO:0006974] 0.752397216 -0.31548 negative regulation of cell growth [GO:0030308] 0.752178866 -0.315768 negative regulation of cell size [GO:0045792] 0.752178866 -0.315768 AP-type membrane coat adaptor complex [GO:0030119] 0.74924833 -0.319631 clathrin adaptor complex [GO:0030131] 0.74924833 -0.319631 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031145] 0.748326832 -0.320846 inositol trisphosphate kinase activity [GO:0051766] 0.747643658 -0.321748 secretion by cell [GO:0032940] 0.746472283 -0.323294 cytoplasmic vesicle membrane [GO:0030659] 0.74524311 -0.324918 chromosome, telomeric region [GO:0000781] 0.744473202 -0.325935 regulation of protein polymerization [GO:0032271] 0.742107924 -0.329063 spliceosomal snRNP biogenesis [GO:0000387] 0.738468097 -0.333883 neuromuscular process controlling balance [GO:0050885] 0.738243728 -0.33418 amino acid metabolic process [GO:0006520] 0.737204139 -0.335558 DNA damage response, signal transduction by p53 class mediator [GO:0030330] 0.736044792 -0.337096 telomere maintenance [GO:0000723] 0.735662746 -0.337603 microtubule motor activity [GO:0003777] 0.735662746 -0.337603 telomere organization and biogenesis [GO:0032200] 0.735662746 -0.337603 organelle outer membrane [GO:0031968] 0.73534911 -0.338019 regulation of apoptosis [GO:0042981] 0.733821802 -0.340046 endosome [GO:0005768] 0.733270241 -0.340779 apicolateral plasma membrane [GO:0016327] 0.732296433 -0.342072 Rho guanyl-nucleotide exchange factor activity [GO:0005089] 0.732277878 -0.342097 regulation of actin filament polymerization [GO:0030833] 0.731824941 -0.342699 GTPase activity [GO:0003924] 0.73053733 -0.344411 general RNA polymerase II transcription factor activity [GO:0016251] 0.729569504 -0.345698 chromatin binding [GO:0003682] 0.728019551 -0.347761 regulation of protein import into nucleus [GO:0042306] 0.727203613 -0.348848 sterol metabolic process [GO:0016125] 0.723050217 -0.354385 positive regulation of protein amino acid phosphorylation [GO:0001934] 0.72225382 -0.355448 membrane coat [GO:0030117] 0.722183311 -0.355542 coated membrane [GO:0048475] 0.722183311 -0.355542 regulation of programmed cell death [GO:0043067] 0.72144458 -0.356529 nucleobase metabolic process [GO:0009112] 0.721338459 -0.356671 multi-organism process [GO:0051704] 0.720616639 -0.357635 mitochondrial envelope [GO:0005740] 0.720422455 -0.357894 cartilage development [GO:0051216] 0.719093044 -0.359671 DNA geometric change [GO:0032392] 0.714030034 -0.366449 DNA duplex unwinding [GO:0032508] 0.714030034 -0.366449 regulation of catalytic activity [GO:0050790] 0.711394729 -0.369984 tubulin binding [GO:0015631] 0.709842284 -0.372068 cytoplasmic sequestering of protein [GO:0051220] 0.709566402 -0.372438 nucleoplasm part [GO:0044451] 0.70913629 -0.373016 transcription initiation [GO:0006352] 0.708367208 -0.37405 glutamine family amino acid metabolic process [GO:0009064] 0.704277098 -0.379553 neural tube closure [GO:0001843] 0.702889528 -0.381423 primary neural tube formation [GO:0014020] 0.702889528 -0.381423 positive regulation of erythrocyte differentiation [GO:0045648] 0.702308112 -0.382207 glycoprotein metabolic process [GO:0009100] 0.69941916 -0.386105 cell activation during immune response [GO:0002263] 0.699202801 -0.386397 leukocyte activation during immune response [GO:0002366] 0.699202801 -0.386397 receptor-mediated endocytosis [GO:0006898] 0.699130143 -0.386495 cellular_component [GO:0005575] 0.697991478 -0.388033 cell [GO:0005623] 0.695192872 -0.391818 cell part [GO:0044464] 0.695192872 -0.391818 G1 phase of mitotic cell cycle [GO:0000080] 0.692500697 -0.395464 regulation of DNA replication initiation [GO:0030174] 0.691709748 -0.396536 cholesterol metabolic process [GO:0008203] 0.687290169 -0.402535 protein localization in organelle [GO:0033365] 0.686832254 -0.403158 fertilization [GO:0009566] 0.686462659 -0.40366 induction of apoptosis by intracellular signals [GO:0008629] 0.68408903 -0.40689 vacuolar part [GO:0044437] 0.682359404 -0.409246 intracellular organelle [GO:0043229] 0.680749847 -0.41144 negative regulation of catalytic activity [GO:0043086] 0.6737774 -0.420969 appendage morphogenesis [GO:0035107] 0.672864849 -0.422219 limb morphogenesis [GO:0035108] 0.672864849 -0.422219 appendage development [GO:0048736] 0.672864849 -0.422219 limb development [GO:0060173] 0.672864849 -0.422219 I-kappaB kinase/NF-kappaB cascade [GO:0007249] 0.66898611 -0.42754 secretion [GO:0046903] 0.668900138 -0.427658 developmental growth [GO:0048589] 0.668672406 -0.427971 stress fiber [GO:0001725] 0.667289085 -0.429872 actin filament bundle [GO:0032432] 0.667289085 -0.429872 voltage-gated potassium channel activity [GO:0005249] 0.666925287 -0.430372 voltage-gated potassium channel complex [GO:0008076] 0.664998211 -0.433023 nucleotide catabolic process [GO:0009166] 0.663495873 -0.435092 eukaryotic translation initiation factor 2B complex [GO:0005851] 0.661508044 -0.437832 positive regulation of I-kappaB kinase/NF-kappaB cascade [GO:0043123] 0.661081655 -0.43842 ribonucleoprotein binding [GO:0043021] 0.660608137 -0.439074 COPI vesicle coat [GO:0030126] 0.655411681 -0.446257 COPI coated vesicle membrane [GO:0030663] 0.655411681 -0.446257 monosaccharide binding [GO:0048029] 0.653023242 -0.449566 organelle [GO:0043226] 0.652745359 -0.449952 lipid transporter activity [GO:0005319] 0.652252575 -0.450635 phospholipid transporter activity [GO:0005548] 0.651965761 -0.451033 RNA elongation [GO:0006354] 0.651894066 -0.451132 RNA elongation from RNA polymerase II promoter [GO:0006368] 0.651894066 -0.451132 neural plate morphogenesis [GO:0001839] 0.650769212 -0.452694 neural plate development [GO:0001840] 0.650769212 -0.452694 neural tube formation [GO:0001841] 0.650769212 -0.452694 phospholipid-translocating ATPase activity [GO:0004012] 0.650231855 -0.45344 aminophospholipid transporter activity [GO:0015247] 0.650231855 -0.45344 interspecies interaction between organisms [GO:0044419] 0.647890783 -0.456694 cyclic-nucleotide phosphodiesterase activity [GO:0004112] 0.643409124 -0.462938 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114] 0.643409124 -0.462938 NADP metabolic process [GO:0006739] 0.64187449 -0.46508 antioxidant activity [GO:0016209] 0.64121639 -0.465999 regulation of immune effector process [GO:0002697] 0.641117879 -0.466136 regulation of cellular protein metabolic process [GO:0032268] 0.638035404 -0.470447 RNA modification [GO:0009451] 0.637786683 -0.470796 mediator complex [GO:0000119] 0.63525207 -0.474348 regulation of endocytosis [GO:0030100] 0.635141723 -0.474502 peptidoglycan metabolic process [GO:0000270] 0.634794282 -0.47499 tissue remodeling [GO:0048771] 0.634083974 -0.475987 lipid transport [GO:0006869] 0.633040399 -0.477452 sensory perception of mechanical stimulus [GO:0050954] 0.631377891 -0.479788 endodeoxyribonuclease activity [GO:0004520] 0.630959237 -0.480377 regulation of hydrolase activity [GO:0051336] 0.62939562 -0.482578 amino acid transport [GO:0006865] 0.628010969 -0.484528 4 iron, 4 sulfur cluster binding [GO:0051539] 0.626035276 -0.487315 negative regulation of transcription factor activity [GO:0043433] 0.623200896 -0.491319 cilium [GO:0005929] 0.622016102 -0.492995 neural tube development [GO:0021915] 0.621528464 -0.493685 mitochondrion [GO:0005739] 0.621436597 -0.493815 receptor signaling complex scaffold activity [GO:0030159] 0.621264953 -0.494058 exocytosis [GO:0006887] 0.620210618 -0.495552 arginine metabolic process [GO:0006525] 0.61866386 -0.497745 nitrogen compound biosynthetic process [GO:0044271] 0.61577363 -0.501849 transmembrane transport [GO:0055085] 0.614877105 -0.503124 iron-sulfur cluster binding [GO:0051536] 0.61108849 -0.50852 metal cluster binding [GO:0051540] 0.61108849 -0.50852 regulation of translation [GO:0006417] 0.609504582 -0.510781 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [GO:0016701] 0.608148521 -0.512718 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702] 0.608148521 -0.512718 dioxygenase activity [GO:0051213] 0.608148521 -0.512718 translational initiation [GO:0006413] 0.607648872 -0.513432 defense response [GO:0006952] 0.606756532 -0.514709 potassium channel regulator activity [GO:0015459] 0.602526108 -0.520771 organelle organization and biogenesis [GO:0006996] 0.602187426 -0.521257 negative regulation of intracellular transport [GO:0032387] 0.600880392 -0.523135 negative regulation of protein transport [GO:0051224] 0.600880392 -0.523135 peptidyl-prolyl cis-trans isomerase activity [GO:0003755] 0.60045827 -0.523742 cis-trans isomerase activity [GO:0016859] 0.60045827 -0.523742 ear development [GO:0043583] 0.598497077 -0.526563 mesoderm development [GO:0007498] 0.597770272 -0.52761 protein amino acid ADP-ribosylation [GO:0006471] 0.597515099 -0.527977 double-strand break repair [GO:0006302] 0.594356053 -0.532534 transcription initiation from RNA polymerase II promoter [GO:0006367] 0.593357588 -0.533977 membrane protein ectodomain proteolysis [GO:0006509] 0.593231724 -0.534159 membrane protein proteolysis [GO:0033619] 0.593231724 -0.534159 deoxyribonuclease activity [GO:0004536] 0.592561316 -0.535128 positive regulation of apoptosis [GO:0043065] 0.589269941 -0.539894 positive regulation of programmed cell death [GO:0043068] 0.589269941 -0.539894 regulation of cell cycle [GO:0051726] 0.58494967 -0.546169 double-stranded RNA binding [GO:0003725] 0.579323223 -0.554374 Ran GTPase binding [GO:0008536] 0.578274196 -0.555907 chromatin remodeling complex [GO:0016585] 0.57781328 -0.556582 protein kinase B signaling cascade [GO:0043491] 0.577119839 -0.557597 Golgi to endosome transport [GO:0006895] 0.576302413 -0.558794 cellular defense response [GO:0006968] 0.575207928 -0.560398 negative regulation of macromolecule biosynthetic process [GO:0010558] 0.57399785 -0.562173 positive regulation of cellular protein metabolic process [GO:0032270] 0.573877343 -0.56235 oxidoreduction coenzyme metabolic process [GO:0006733] 0.573192117 -0.563357 non-membrane spanning protein tyrosine phosphatase activity [GO:0004726] 0.571816366 -0.565378 T cell receptor signaling pathway [GO:0050852] 0.569782757 -0.568371 transition metal ion transport [GO:0000041] 0.569459721 -0.568847 inner ear receptor cell differentiation [GO:0060113] 0.569015815 -0.569502 nuclear body [GO:0016604] 0.567241525 -0.572119 sterol transporter activity [GO:0015248] 0.565750578 -0.574321 chaperone binding [GO:0051087] 0.565725919 -0.574357 structure-specific DNA binding [GO:0043566] 0.565675826 -0.574432 induction of apoptosis [GO:0006917] 0.562746581 -0.578767 induction of programmed cell death [GO:0012502] 0.562746581 -0.578767 mRNA metabolic process [GO:0016071] 0.56224069 -0.579517 regulation of Wnt receptor signaling pathway [GO:0030111] 0.559049395 -0.584254 phosphatidylinositol binding [GO:0005545] 0.558877616 -0.584509 glycoprotein biosynthetic process [GO:0009101] 0.55815192 -0.585589 RNA splicing, via transesterification reactions [GO:0000375] 0.557365986 -0.586758 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [GO:0000377] 0.557365986 -0.586758 nuclear mRNA splicing, via spliceosome [GO:0000398] 0.557365986 -0.586758 sialyltransferase activity [GO:0008373] 0.556046502 -0.588724 ear morphogenesis [GO:0042471] 0.552759409 -0.59363 selenium binding [GO:0008430] 0.551158418 -0.596025 guanyl-nucleotide exchange factor activity [GO:0005085] 0.549824449 -0.598023 erythrocyte homeostasis [GO:0034101] 0.548877454 -0.599443 cellular process [GO:0009987] 0.547914399 -0.600888 negative regulation of MAP kinase activity [GO:0043407] 0.547230707 -0.601915 apical plasma membrane [GO:0016324] 0.546707647 -0.602701 nuclear outer membrane [GO:0005640] 0.546448606 -0.60309 dorsal/ventral pattern formation [GO:0009953] 0.546034885 -0.603712 monovalent inorganic cation homeostasis [GO:0055067] 0.543861402 -0.606984 microtubule associated complex [GO:0005875] 0.542477431 -0.609071 RNA polymerase II transcription mediator activity [GO:0016455] 0.542122041 -0.609607 regulation of transcription from RNA polymerase II promoter [GO:0006357] 0.540950833 -0.611376 ATPase activity, coupled to transmembrane movement of ions [GO:0042625] 0.540345839 -0.61229 pyrimidine base metabolic process [GO:0006206] 0.540311935 -0.612341 activation of protein kinase C activity [GO:0007205] 0.540287598 -0.612378 DNA unwinding during replication [GO:0006268] 0.539249791 -0.613948 nuclear matrix [GO:0016363] 0.53776376 -0.616198 RNA processing [GO:0006396] 0.537107355 -0.617193 protein targeting [GO:0006605] 0.535681457 -0.619357 rhythmic process [GO:0048511] 0.528505341 -0.630289 sulfur amino acid metabolic process [GO:0000096] 0.526719205 -0.633022 zinc ion transport [GO:0006829] 0.522134285 -0.640059 anchored to membrane [GO:0031225] 0.52187466 -0.640458 interphase of mitotic cell cycle [GO:0051329] 0.519867971 -0.643549 response to biotic stimulus [GO:0009607] 0.519755199 -0.643723 transport vesicle membrane [GO:0030658] 0.517805771 -0.646731 Golgi-associated vesicle membrane [GO:0030660] 0.517805771 -0.646731 mitotic cell cycle [GO:0000278] 0.515508617 -0.650284 negative regulation of transport [GO:0051051] 0.515354849 -0.650522 Ras guanyl-nucleotide exchange factor activity [GO:0005088] 0.509823696 -0.659112 regulation of ubiquitin-protein ligase activity during mitotic cell cycle [GO:0051439] 0.50600534 -0.665071 ubiquinone metabolic process [GO:0006743] 0.50277262 -0.670134 ubiquinone biosynthetic process [GO:0006744] 0.50277262 -0.670134 quinone cofactor metabolic process [GO:0042375] 0.50277262 -0.670134 quinone cofactor biosynthetic process [GO:0045426] 0.50277262 -0.670134 cytosol [GO:0005829] 0.502162307 -0.671091 anion transport [GO:0006820] 0.499640024 -0.675056 sensory perception of sound [GO:0007605] 0.499527201 -0.675234 enzyme activator activity [GO:0008047] 0.498192396 -0.677337 inactivation of MAPK activity [GO:0000188] 0.494898295 -0.682539 nucleotidyltransferase activity [GO:0016779] 0.494241244 -0.683579 nucleocytoplasmic transport [GO:0006913] 0.492083781 -0.686998 nuclear transport [GO:0051169] 0.492083781 -0.686998 response to mechanical stimulus [GO:0009612] 0.490538247 -0.689453 negative regulation of protein kinase activity [GO:0006469] 0.490361683 -0.689734 negative regulation of kinase activity [GO:0033673] 0.490361683 -0.689734 negative regulation of transferase activity [GO:0051348] 0.490361683 -0.689734 organic acid transport [GO:0015849] 0.488152971 -0.69325 carboxylic acid transport [GO:0046942] 0.488152971 -0.69325 diacylglycerol binding [GO:0019992] 0.486723797 -0.695529 somatic recombination of immunoglobulin genes during immune response [GO:0002204] 0.486133257 -0.696472 somatic diversification of immunoglobulins during immune response [GO:0002208] 0.486133257 -0.696472 immunoglobulin production during immune response [GO:0002381] 0.486133257 -0.696472 isotype switching [GO:0045190] 0.486133257 -0.696472 DNA-directed DNA polymerase activity [GO:0003887] 0.485245703 -0.69789 DNA polymerase activity [GO:0034061] 0.485245703 -0.69789 bone remodeling [GO:0046849] 0.484095531 -0.699731 positive regulation of signal transduction [GO:0009967] 0.48401643 -0.699857 positive regulation of protein modification process [GO:0031401] 0.483689713 -0.70038 kinase regulator activity [GO:0019207] 0.483677611 -0.7004 vesicle localization [GO:0051648] 0.482403 -0.702443 establishment of vesicle localization [GO:0051650] 0.482403 -0.702443 protein transport [GO:0015031] 0.481358332 -0.70412 regulation of cytokine production [GO:0001817] 0.478209538 -0.709185 ER to Golgi vesicle-mediated transport [GO:0006888] 0.476366432 -0.712159 NADP binding [GO:0050661] 0.476322801 -0.712229 RNA export from nucleus [GO:0006405] 0.474857856 -0.714597 U12-dependent spliceosome [GO:0005689] 0.474591326 -0.715029 RNA splicing [GO:0008380] 0.47329029 -0.717136 mitochondrion organization and biogenesis [GO:0007005] 0.471165674 -0.720584 negative regulation of protein import into nucleus [GO:0042308] 0.469234688 -0.723725 regulation of transcription factor import into nucleus [GO:0042990] 0.469234688 -0.723725 transcription factor import into nucleus [GO:0042991] 0.469234688 -0.723725 negative regulation of transcription factor import into nucleus [GO:0042992] 0.469234688 -0.723725 steroid metabolic process [GO:0008202] 0.468608071 -0.724746 DNA-directed RNA polymerase complex [GO:0000428] 0.466656596 -0.72793 RNA polymerase complex [GO:0030880] 0.466656596 -0.72793 nuclear DNA-directed RNA polymerase complex [GO:0055029] 0.466656596 -0.72793 protein metabolic process [GO:0019538] 0.465960204 -0.729068 lipid binding [GO:0008289] 0.46375568 -0.732677 proteasome complex [GO:0000502] 0.463093264 -0.733763 regulation of catabolic process [GO:0009894] 0.461555193 -0.736288 regulation of ubiquitin-protein ligase activity [GO:0051438] 0.460986364 -0.737224 anaphase-promoting complex [GO:0005680] 0.460495135 -0.738032 immunoglobulin production [GO:0002377] 0.458930952 -0.740608 establishment of organelle localization [GO:0051656] 0.45889862 -0.740662 cellular macromolecule metabolic process [GO:0044260] 0.4578424 -0.742404 protein N-terminus binding [GO:0047485] 0.457354521 -0.74321 G1/S transition of mitotic cell cycle [GO:0000082] 0.456208556 -0.745104 negative regulation of transcription [GO:0016481] 0.455135064 -0.746882 motor activity [GO:0003774] 0.453979858 -0.748797 in utero embryonic development [GO:0001701] 0.452573365 -0.751132 monocarboxylic acid transmembrane transporter activity [GO:0008028] 0.451665258 -0.752642 initiation of viral infection [GO:0019059] 0.450527241 -0.754536 protein polyubiquitination [GO:0000209] 0.447812084 -0.759068 ossification [GO:0001503] 0.447512371 -0.759569 biomineral formation [GO:0031214] 0.447512371 -0.759569 pyrimidine nucleotide metabolic process [GO:0006220] 0.445953312 -0.762179 pyrimidine nucleotide biosynthetic process [GO:0006221] 0.445953312 -0.762179 cytoplasmic sequestering of transcription factor [GO:0042994] 0.445156118 -0.763515 positive regulation of catalytic activity [GO:0043085] 0.443435651 -0.766405 neutral amino acid transmembrane transporter activity [GO:0015175] 0.441431824 -0.769778 lung development [GO:0030324] 0.437596263 -0.776259 mRNA processing [GO:0006397] 0.436636031 -0.777886 phosphorylase kinase regulator activity [GO:0008607] 0.434524137 -0.781473 early endosome membrane [GO:0031901] 0.431019057 -0.787449 oogenesis [GO:0048477] 0.431013003 -0.787459 response to virus [GO:0009615] 0.430941194 -0.787582 response to oxidative stress [GO:0006979] 0.430831161 -0.78777 Ras GTPase binding [GO:0017016] 0.429703797 -0.789699 RNA polymerase II transcription factor activity [GO:0003702] 0.429179097 -0.790597 gene silencing [GO:0016458] 0.42792481 -0.792748 1-acylglycerol-3-phosphate O-acyltransferase activity [GO:0003841] 0.427867099 -0.792847 acylglycerol O-acyltransferase activity [GO:0016411] 0.427867099 -0.792847 vesicle coat [GO:0030120] 0.424257131 -0.799057 coated vesicle membrane [GO:0030662] 0.424257131 -0.799057 mammary gland development [GO:0030879] 0.423866849 -0.799731 mitochondrial transport [GO:0006839] 0.422887564 -0.801422 antiporter activity [GO:0015297] 0.420810215 -0.805016 establishment of protein localization [GO:0045184] 0.420746726 -0.805126 group transfer coenzyme metabolic process [GO:0006752] 0.417477776 -0.810805 coenzyme A metabolic process [GO:0015936] 0.417477776 -0.810805 actin filament-based process [GO:0030029] 0.417095979 -0.81147 phospholipid transport [GO:0015914] 0.414597149 -0.81583 COPI-coated vesicle [GO:0030137] 0.410321861 -0.823327 sterol transport [GO:0015918] 0.409865354 -0.824131 cholesterol transport [GO:0030301] 0.409865354 -0.824131 phagocytosis [GO:0006909] 0.409429313 -0.824898 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [GO:0016628] 0.408801344 -0.826005 GTPase regulator activity [GO:0030695] 0.406893451 -0.829373 GTPase binding [GO:0051020] 0.40386071 -0.834746 protein complex scaffold [GO:0032947] 0.401642769 -0.838691 regulation of pH [GO:0006885] 0.39835752 -0.844558 negative regulation of nucleocytoplasmic transport [GO:0046823] 0.396143563 -0.848529 biosynthetic process [GO:0009058] 0.392379253 -0.855311 cation:cation antiporter activity [GO:0015491] 0.39183271 -0.856298 nuclear ubiquitin ligase complex [GO:0000152] 0.391305049 -0.857253 lysine N-methyltransferase activity [GO:0016278] 0.390522502 -0.85867 protein-lysine N-methyltransferase activity [GO:0016279] 0.390522502 -0.85867 histone-lysine N-methyltransferase activity [GO:0018024] 0.390522502 -0.85867 adherens junction [GO:0005912] 0.388961634 -0.861502 protein localization [GO:0008104] 0.385169739 -0.86841 ligand-dependent nuclear receptor transcription coactivator activity [GO:0030374] 0.382562215 -0.873185 response to other organism [GO:0051707] 0.378856565 -0.880005 RNA-dependent DNA replication [GO:0006278] 0.378673786 -0.880343 telomere maintenance via telomerase [GO:0007004] 0.378673786 -0.880343 vacuolar transport [GO:0007034] 0.377938345 -0.881701 single fertilization [GO:0007338] 0.376593244 -0.884191 glutamine family amino acid biosynthetic process [GO:0009084] 0.374276296 -0.888492 specific RNA polymerase II transcription factor activity [GO:0003704] 0.373323857 -0.890265 DNA repair [GO:0006281] 0.372183007 -0.892392 transferase activity, transferring alkyl or aryl (other than methyl) groups [GO:0016765] 0.370579969 -0.895388 regulation of gene expression, epigenetic [GO:0040029] 0.370346609 -0.895824 regulation of ligase activity [GO:0051340] 0.369107915 -0.898146 protein import into peroxisome matrix [GO:0016558] 0.363063862 -0.909542 amine biosynthetic process [GO:0009309] 0.362341223 -0.910913 GTPase activator activity [GO:0005096] 0.361477933 -0.912553 protein export from nucleus [GO:0006611] 0.360164475 -0.915052 early endosome [GO:0005769] 0.358716556 -0.917813 negative regulation of transcription from RNA polymerase II promoter [GO:0000122] 0.357510753 -0.920119 G2/M transition of mitotic cell cycle [GO:0000086] 0.356141071 -0.922743 gastrulation with mouth forming second [GO:0001702] 0.35551737 -0.92394 oligosaccharide biosynthetic process [GO:0009312] 0.353961135 -0.926933 lipoprotein metabolic process [GO:0042157] 0.349349167 -0.935852 positive regulation of osteoblast differentiation [GO:0045669] 0.343988611 -0.946314 ER-Golgi intermediate compartment [GO:0005793] 0.343653853 -0.94697 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [GO:0006139] 0.341800332 -0.950614 Golgi organization and biogenesis [GO:0007030] 0.338735751 -0.956666 spermatid development [GO:0007286] 0.335914862 -0.962268 DNA modification [GO:0006304] 0.335856232 -0.962385 spermatid differentiation [GO:0048515] 0.335221485 -0.96365 determination of left/right symmetry [GO:0007368] 0.335088553 -0.963915 determination of symmetry [GO:0009799] 0.335088553 -0.963915 determination of bilateral symmetry [GO:0009855] 0.335088553 -0.963915 collagen [GO:0005581] 0.334159442 -0.96577 cellular protein metabolic process [GO:0044267] 0.331576497 -0.970943 serine family amino acid metabolic process [GO:0009069] 0.330027449 -0.974059 small GTPase binding [GO:0031267] 0.32257806 -0.989174 endosome membrane [GO:0010008] 0.320660921 -0.993101 endosomal part [GO:0044440] 0.320660921 -0.993101 negative regulation of cell cycle [GO:0045786] 0.320167494 -0.994114 cell cycle [GO:0007049] 0.319265974 -0.995967 insulin receptor signaling pathway [GO:0008286] 0.3191551 -0.996196 tRNA binding [GO:0000049] 0.317596953 -0.999408 negative regulation of ligase activity [GO:0051352] 0.316799572 -1.001056 negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle [GO:0051436] 0.316799572 -1.001056 negative regulation of ubiquitin-protein ligase activity [GO:0051444] 0.316799572 -1.001056 negative regulation of transcription, DNA-dependent [GO:0045892] 0.315771338 -1.003186 positive regulation of cellular component organization and biogenesis [GO:0051130] 0.315719877 -1.003292 cell proliferation in hindbrain [GO:0021534] 0.314440263 -1.005949 cell proliferation in the external granule layer [GO:0021924] 0.314440263 -1.005949 granule cell precursor proliferation [GO:0021930] 0.314440263 -1.005949 regulation of granule cell precursor proliferation [GO:0021936] 0.314440263 -1.005949 positive regulation of granule cell precursor proliferation [GO:0021940] 0.314440263 -1.005949 male meiosis [GO:0007140] 0.314152385 -1.006547 purine nucleotide catabolic process [GO:0006195] 0.313002608 -1.008942 production of molecular mediator of immune response [GO:0002440] 0.312727361 -1.009516 macromolecule localization [GO:0033036] 0.312117402 -1.010789 calcium-dependent cysteine-type endopeptidase activity [GO:0004198] 0.311879102 -1.011287 protein prenylation [GO:0018342] 0.311283144 -1.012533 protein amino acid prenylation [GO:0018346] 0.311283144 -1.012533 covalent chromatin modification [GO:0016569] 0.309086353 -1.017141 transforming growth factor beta receptor signaling pathway [GO:0007179] 0.308920134 -1.017491 sulfur compound biosynthetic process [GO:0044272] 0.308794015 -1.017756 extracellular matrix organization and biogenesis [GO:0030198] 0.308723237 -1.017905 regulation of Rab GTPase activity [GO:0032313] 0.308254055 -1.018892 Rab protein signal transduction [GO:0032482] 0.308254055 -1.018892 regulation of Rab protein signal transduction [GO:0032483] 0.308254055 -1.018892 epithelial cell differentiation [GO:0030855] 0.302955113 -1.030117 response to bacterium [GO:0009617] 0.301377311 -1.033484 translation factor activity, nucleic acid binding [GO:0008135] 0.301138208 -1.033996 protein targeting to peroxisome [GO:0006625] 0.299845504 -1.036765 peroxisomal transport [GO:0043574] 0.299845504 -1.036765 extracellular matrix structural constituent [GO:0005201] 0.297758287 -1.041253 Rho GTPase binding [GO:0017048] 0.297003263 -1.042881 erythrocyte differentiation [GO:0030218] 0.296506264 -1.043955 translation regulator activity [GO:0045182] 0.296088863 -1.044857 fucosyltransferase activity [GO:0008417] 0.294431638 -1.048449 negative regulation of RNA metabolic process [GO:0051253] 0.29162886 -1.054555 chromatin modification [GO:0016568] 0.289758616 -1.058651 solute:cation antiporter activity [GO:0015298] 0.289260982 -1.059744 solute:solute antiporter activity [GO:0015300] 0.289260982 -1.059744 smoothened signaling pathway [GO:0007224] 0.288594026 -1.061211 protein import into nucleus, docking [GO:0000059] 0.288576676 -1.061249 vesicle organization and biogenesis [GO:0016050] 0.288336443 -1.061778 biological regulation [GO:0065007] 0.284023375 -1.071325 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [GO:0015662] 0.283414875 -1.07268 nucleobase biosynthetic process [GO:0046112] 0.283329818 -1.072869 flagellum [GO:0019861] 0.283089589 -1.073405 cell-substrate junction [GO:0030055] 0.282857233 -1.073923 defense response to virus [GO:0051607] 0.282747619 -1.074167 protein transporter activity [GO:0008565] 0.281883906 -1.076097 protein tyrosine/serine/threonine phosphatase activity [GO:0008138] 0.281365927 -1.077256 chromosome organization and biogenesis [GO:0051276] 0.280566343 -1.079048 Wnt receptor activity [GO:0042813] 0.279265427 -1.081971 DNA-directed RNA polymerase II, core complex [GO:0005665] 0.27773067 -1.085431 prenyltransferase activity [GO:0004659] 0.274934385 -1.09177 protein amino acid lipidation [GO:0006497] 0.274577798 -1.092581 lipoprotein biosynthetic process [GO:0042158] 0.274577798 -1.092581 negative regulation of binding [GO:0051100] 0.274572452 -1.092593 cell projection biogenesis [GO:0030031] 0.273772149 -1.094417 viral reproduction [GO:0016032] 0.272985488 -1.096213 mannosidase activity [GO:0015923] 0.271954336 -1.098573 regulation of biological process [GO:0050789] 0.270459454 -1.102005 regulation of nucleocytoplasmic transport [GO:0046822] 0.270015555 -1.103027 respiratory tube development [GO:0030323] 0.269314499 -1.104643 androgen receptor binding [GO:0050681] 0.26853717 -1.106438 Golgi-associated vesicle [GO:0005798] 0.26847417 -1.106583 polyamine metabolic process [GO:0006595] 0.266953693 -1.110105 Golgi membrane [GO:0000139] 0.266233134 -1.111779 intra-Golgi vesicle-mediated transport [GO:0006891] 0.265922679 -1.112501 viral reproductive process [GO:0022415] 0.263869566 -1.117292 negative regulation of DNA binding [GO:0043392] 0.262011248 -1.12165 Rho GTPase activator activity [GO:0005100] 0.258619332 -1.12966 nuclear export [GO:0051168] 0.257380712 -1.132604 amino acid biosynthetic process [GO:0008652] 0.254639815 -1.139152 SNAP receptor activity [GO:0005484] 0.251273465 -1.147262 positive regulation of protein metabolic process [GO:0051247] 0.251063506 -1.14777 pyrimidine ribonucleotide metabolic process [GO:0009218] 0.249661018 -1.151173 pyrimidine ribonucleotide biosynthetic process [GO:0009220] 0.249661018 -1.151173 small GTPase regulator activity [GO:0005083] 0.247012921 -1.157635 vesicle targeting [GO:0006903] 0.240525479 -1.173674 oligosaccharide metabolic process [GO:0009311] 0.239784539 -1.175526 regulation of osteoblast differentiation [GO:0045667] 0.238904132 -1.17773 myeloid cell differentiation [GO:0030099] 0.23823765 -1.179403 carbon-carbon lyase activity [GO:0016830] 0.238131589 -1.17967 cell cortex [GO:0005938] 0.235011863 -1.187547 tRNA metabolic process [GO:0006399] 0.233125704 -1.192346 establishment and/or maintenance of chromatin architecture [GO:0006325] 0.230996854 -1.197795 inward rectifier potassium channel activity [GO:0005242] 0.228787944 -1.203487 integral to membrane of membrane fraction [GO:0000299] 0.222484414 -1.219948 development of primary male sexual characteristics [GO:0046546] 0.222144197 -1.220846 male sex differentiation [GO:0046661] 0.222144197 -1.220846 Golgi vesicle transport [GO:0048193] 0.221442823 -1.222701 actin cytoskeleton organization and biogenesis [GO:0030036] 0.220283621 -1.225774 prefoldin complex [GO:0016272] 0.219211248 -1.228628 microbody part [GO:0044438] 0.218754515 -1.229847 peroxisomal part [GO:0044439] 0.218754515 -1.229847 dynein complex [GO:0030286] 0.218582389 -1.230306 membrane budding [GO:0006900] 0.217178741 -1.234065 vesicle coating [GO:0006901] 0.217178741 -1.234065 GPI-anchor transamidase activity [GO:0003923] 0.215196296 -1.239403 non-G-protein coupled 7TM receptor activity [GO:0004926] 0.215196296 -1.239403 attachment of GPI anchor to protein [GO:0016255] 0.215196296 -1.239403 GPI-anchor transamidase complex [GO:0042765] 0.215196296 -1.239403 retrograde transport, endosome to Golgi [GO:0042147] 0.214974807 -1.240002 cyclic nucleotide binding [GO:0030551] 0.213869827 -1.242995 tRNA processing [GO:0008033] 0.211690872 -1.248929 iron ion homeostasis [GO:0055072] 0.211451792 -1.249583 somatic recombination of immunoglobulin gene segments [GO:0016447] 0.20717763 -1.261364 binding [GO:0005488] 0.205064639 -1.267254 positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [GO:0051437] 0.204316856 -1.269348 positive regulation of ubiquitin-protein ligase activity [GO:0051443] 0.204316856 -1.269348 regulation of NF-kappaB import into nucleus [GO:0042345] 0.203895822 -1.27053 negative regulation of NF-kappaB import into nucleus [GO:0042347] 0.203895822 -1.27053 NF-kappaB import into nucleus [GO:0042348] 0.203895822 -1.27053 androgen receptor signaling pathway [GO:0030521] 0.202750964 -1.273753 aspartate family amino acid metabolic process [GO:0009066] 0.202689298 -1.273927 cullin-RING ubiquitin ligase complex [GO:0031461] 0.202397134 -1.274752 viral infectious cycle [GO:0019058] 0.201982373 -1.275924 single-stranded DNA binding [GO:0003697] 0.200551299 -1.279982 microtubule binding [GO:0008017] 0.20054574 -1.279998 peroxisomal membrane [GO:0005778] 0.197999591 -1.287272 microbody membrane [GO:0031903] 0.197999591 -1.287272 regulation of myoblast differentiation [GO:0045661] 0.196744371 -1.290883 regulation of muscle cell differentiation [GO:0051147] 0.196744371 -1.290883 regulation of protein catabolic process [GO:0042176] 0.196046805 -1.292897 stress-activated protein kinase signaling pathway [GO:0031098] 0.195665797 -1.293999 spliceosome [GO:0005681] 0.192833249 -1.302243 formation of primary germ layer [GO:0001704] 0.190170923 -1.310074 mesoderm formation [GO:0001707] 0.190170923 -1.310074 protein prenyltransferase activity [GO:0008318] 0.189982781 -1.31063 Rab GTPase activator activity [GO:0005097] 0.188756146 -1.314268 protein geranylgeranyltransferase activity [GO:0004661] 0.187764526 -1.317221 regulation of Ras GTPase activity [GO:0032318] 0.187519237 -1.317953 odontogenesis of dentine-containing teeth [GO:0042475] 0.185408479 -1.324285 odontogenesis [GO:0042476] 0.185408479 -1.324285 endosome transport [GO:0016197] 0.183910285 -1.328811 somatic diversification of immunoglobulins [GO:0016445] 0.182193712 -1.334031 biopolymer biosynthetic process [GO:0043284] 0.181305618 -1.336746 RNA methyltransferase activity [GO:0008173] 0.180948937 -1.337839 transcription factor TFIID complex [GO:0005669] 0.177277273 -1.349186 response to dsRNA [GO:0043331] 0.176933604 -1.350257 protein targeting to mitochondrion [GO:0006626] 0.176777857 -1.350743 RNA cap binding [GO:0000339] 0.176586116 -1.351341 oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627] 0.176440951 -1.351795 translation initiation factor activity [GO:0003743] 0.176355582 -1.352062 transcription, DNA-dependent [GO:0006351] 0.17339098 -1.361388 RNA biosynthetic process [GO:0032774] 0.17339098 -1.361388 endocytosis [GO:0006897] 0.173213819 -1.36195 membrane invagination [GO:0010324] 0.173213819 -1.36195 regulation of cellular process [GO:0050794] 0.172282635 -1.364906 nuclear heterochromatin [GO:0005720] 0.168999647 -1.375425 regulation of signal transduction [GO:0009966] 0.167347691 -1.380777 thyroid hormone receptor binding [GO:0046966] 0.166675091 -1.382967 Golgi apparatus part [GO:0044431] 0.164517561 -1.390037 solute:hydrogen antiporter activity [GO:0015299] 0.160217001 -1.404342 ubiquitin protein ligase binding [GO:0031625] 0.158471019 -1.410233 cell-substrate adherens junction [GO:0005924] 0.158266568 -1.410926 neutral amino acid transport [GO:0015804] 0.157656541 -1.412997 aspartate family amino acid biosynthetic process [GO:0009067] 0.156002828 -1.418644 positive regulation of ligase activity [GO:0051351] 0.15347423 -1.427367 gastrulation [GO:0007369] 0.152743002 -1.429909 vesicle targeting, to, from or within Golgi [GO:0048199] 0.152338358 -1.431321 histone modification [GO:0016570] 0.151674261 -1.433643 integral to peroxisomal membrane [GO:0005779] 0.151561707 -1.434037 intrinsic to peroxisomal membrane [GO:0031231] 0.151561707 -1.434037 membrane fusion [GO:0006944] 0.151016177 -1.435951 leading edge [GO:0031252] 0.147871029 -1.447092 pyrimidine base biosynthetic process [GO:0019856] 0.147864026 -1.447117 spermatogenesis [GO:0007283] 0.146581935 -1.451711 male gamete generation [GO:0048232] 0.146581935 -1.451711 nuclear inner membrane [GO:0005637] 0.142814866 -1.465389 histone methyltransferase activity [GO:0042054] 0.141310086 -1.47093 amyloid precursor protein metabolic process [GO:0042982] 0.140466917 -1.474055 tissue morphogenesis [GO:0048729] 0.139755305 -1.476703 N-glycan processing [GO:0006491] 0.139182197 -1.478843 regulation of Rho protein signal transduction [GO:0035023] 0.135937291 -1.491092 small GTPase mediated signal transduction [GO:0007264] 0.132069159 -1.505992 Golgi vesicle budding [GO:0048194] 0.131633087 -1.507693 Golgi transport vesicle coating [GO:0048200] 0.131633087 -1.507693 vesicle targeting, inter-Golgi cisterna [GO:0048204] 0.131633087 -1.507693 COPI coating of Golgi vesicle [GO:0048205] 0.131633087 -1.507693 vesicle targeting, cis-Golgi to rough ER [GO:0048206] 0.131633087 -1.507693 inter-Golgi cisterna vesicle-mediated transport [GO:0048219] 0.131633087 -1.507693 cis-Golgi to rough ER vesicle-mediated transport [GO:0048220] 0.131633087 -1.507693 macromolecule metabolic process [GO:0043170] 0.130915402 -1.510502 RNA metabolic process [GO:0016070] 0.129217128 -1.517196 organelle localization [GO:0051640] 0.12915309 -1.51745 molecular_function [GO:0003674] 0.12693537 -1.526299 proteasomal protein catabolic process [GO:0010498] 0.121757415 -1.547439 proteasomal ubiquitin-dependent protein catabolic process [GO:0043161] 0.121757415 -1.547439 membrane organization and biogenesis [GO:0016044] 0.121368141 -1.549056 catabolic process [GO:0009056] 0.120462076 -1.552837 proteasome regulatory particle [GO:0005838] 0.116733377 -1.568633 proteasome accessory complex [GO:0022624] 0.116733377 -1.568633 monocarboxylic acid transport [GO:0015718] 0.116459128 -1.569811 reproduction [GO:0000003] 0.115001646 -1.576105 lamellipodium [GO:0030027] 0.113313957 -1.583472 cell cortex part [GO:0044448] 0.112894833 -1.585315 cofactor transport [GO:0051181] 0.111987043 -1.589325 N-methyltransferase activity [GO:0008170] 0.110555081 -1.595703 transcription elongation regulator activity [GO:0003711] 0.109217161 -1.601722 gene silencing by RNA [GO:0031047] 0.107765618 -1.608318 diacylglycerol kinase activity [GO:0004143] 0.106110984 -1.615923 Ras protein signal transduction [GO:0007265] 0.104509703 -1.623373 vesicle-mediated transport [GO:0016192] 0.101511277 -1.637571 peroxisome organization and biogenesis [GO:0007031] 0.101381772 -1.638191 transcription elongation factor complex [GO:0008023] 0.100679671 -1.641567 regulation of cellular metabolic process [GO:0031323] 0.099034466 -1.649553 apical part of cell [GO:0045177] 0.097251479 -1.658327 regulation of protein metabolic process [GO:0051246] 0.092270356 -1.683541 Rho protein signal transduction [GO:0007266] 0.090412641 -1.693225 regulation of transcription, DNA-dependent [GO:0006355] 0.086126171 -1.716196 SNARE complex [GO:0031201] 0.084983717 -1.722474 DNA binding [GO:0003677] 0.084421873 -1.725586 transcription [GO:0006350] 0.083712513 -1.72954 regulation of GTPase activity [GO:0043087] 0.082153737 -1.738324 protein methyltransferase activity [GO:0008276] 0.081605814 -1.741444 smooth muscle cell proliferation [GO:0048659] 0.081154997 -1.744023 regulation of smooth muscle cell proliferation [GO:0048660] 0.081154997 -1.744023 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [GO:0019219] 0.078940964 -1.756864 nuclear hormone receptor binding [GO:0035257] 0.078539472 -1.759224 methylation [GO:0032259] 0.07806201 -1.762043 biopolymer methylation [GO:0043414] 0.07806201 -1.762043 hormone receptor binding [GO:0051427] 0.077848626 -1.763308 regulation of Ras protein signal transduction [GO:0046578] 0.077218554 -1.767058 carboxy-lyase activity [GO:0016831] 0.076721339 -1.770035 protein binding [GO:0005515] 0.075571553 -1.77698 positive regulation of neurogenesis [GO:0050769] 0.075478594 -1.777545 macromolecule biosynthetic process [GO:0009059] 0.074593475 -1.782956 regulation of RNA metabolic process [GO:0051252] 0.074157795 -1.785639 JNK cascade [GO:0007254] 0.074134788 -1.785781 somatic diversification of immune receptors [GO:0002200] 0.073763831 -1.788075 somatic diversification of immune receptors via germline recombination within a single locus [GO:0002562] 0.073763831 -1.788075 somatic cell DNA recombination [GO:0016444] 0.073763831 -1.788075 phosphoinositide binding [GO:0035091] 0.072476196 -1.796115 DNA-directed RNA polymerase II, holoenzyme [GO:0016591] 0.070047068 -1.811606 regulation of survival gene product expression [GO:0045884] 0.069853021 -1.812863 transition metal ion binding [GO:0046914] 0.069160708 -1.817368 cell cycle arrest [GO:0007050] 0.069042786 -1.81814 mesoderm morphogenesis [GO:0048332] 0.067426338 -1.828822 protein ubiquitination during ubiquitin-dependent protein catabolic process [GO:0042787] 0.066859639 -1.832616 cellular catabolic process [GO:0044248] 0.066602976 -1.834344 protein C-terminus binding [GO:0008022] 0.065645313 -1.840838 ER-Golgi intermediate compartment membrane [GO:0033116] 0.064177179 -1.850947 collagen binding [GO:0005518] 0.063334281 -1.856837 biological_process [GO:0008150] 0.061904984 -1.866976 regulation of small GTPase mediated signal transduction [GO:0051056] 0.060732582 -1.875437 Ras GTPase activator activity [GO:0005099] 0.059711663 -1.882917 regulation of metabolic process [GO:0019222] 0.059703645 -1.882976 cofactor transporter activity [GO:0051184] 0.059130154 -1.887224 macroautophagy [GO:0016236] 0.058111245 -1.894858 Wnt receptor signaling pathway [GO:0016055] 0.055468501 -1.915188 phospholipid binding [GO:0005543] 0.054505759 -1.922795 vitamin transport [GO:0051180] 0.054089551 -1.926119 RNA binding [GO:0003723] 0.051893251 -1.944018 endocytic vesicle [GO:0030139] 0.051400566 -1.94812 regulation of transcription [GO:0045449] 0.048448653 -1.973412 DNA topological change [GO:0006265] 0.047182201 -1.984661 retrograde vesicle-mediated transport, Golgi to ER [GO:0006890] 0.04709245 -1.985468 gene expression [GO:0010467] 0.046841065 -1.987734 gamete generation [GO:0007276] 0.045088697 -2.003826 proteolysis [GO:0006508] 0.044917615 -2.005425 perinuclear region of cytoplasm [GO:0048471] 0.044157404 -2.012594 GTP-dependent protein binding [GO:0030742] 0.04375954 -2.016387 sexual reproduction [GO:0019953] 0.04148756 -2.038624 osteoblast differentiation [GO:0001649] 0.039795282 -2.055868 focal adhesion [GO:0005925] 0.038434768 -2.070188 Golgi apparatus [GO:0005794] 0.037586905 -2.079331 cellular iron ion homeostasis [GO:0006879] 0.03370893 -2.123536 one-carbon compound metabolic process [GO:0006730] 0.03356678 -2.125238 S-adenosylmethionine-dependent methyltransferase activity [GO:0008757] 0.031439683 -2.151463 integral to organelle membrane [GO:0031301] 0.029542031 -2.176177 regulation of protein stability [GO:0031647] 0.02824479 -2.19387 response to osmotic stress [GO:0006970] 0.024841723 -2.243855 misfolded or incompletely synthesized protein catabolic process [GO:0006515] 0.023524576 -2.264806 ER-associated protein catabolic process [GO:0030433] 0.023524576 -2.264806 steroid hormone receptor binding [GO:0035258] 0.021499165 -2.299102 Golgi stack [GO:0005795] 0.018649573 -2.352462 nucleic acid binding [GO:0003676] 0.017208157 -2.38223 vitamin transporter activity [GO:0051183] 0.016865845 -2.389619 regulation of gene expression [GO:0010468] 0.016581929 -2.395849 protein amino acid methylation [GO:0006479] 0.016474724 -2.398225 protein amino acid alkylation [GO:0008213] 0.016474724 -2.398225 intrinsic to organelle membrane [GO:0031300] 0.015204123 -2.42748 protein modification process [GO:0006464] 0.014648282 -2.44096 integral to endoplasmic reticulum membrane [GO:0030176] 0.0145736 -2.442805 intrinsic to endoplasmic reticulum membrane [GO:0031227] 0.0145736 -2.442805 protein stabilization [GO:0050821] 0.010673909 -2.553197 steroid hormone receptor signaling pathway [GO:0030518] 0.01040459 -2.562085 zinc ion binding [GO:0008270] 0.010111108 -2.572006 autophagy [GO:0006914] 0.00966484 -2.587596 estrogen receptor binding [GO:0030331] 0.009181124 -2.605235 biopolymer modification [GO:0043412] 0.008605918 -2.627325 intracellular receptor-mediated signaling pathway [GO:0030522] 0.008232946 -2.642364 cortical cytoskeleton organization and biogenesis [GO:0030865] 0.006946664 -2.69939 cortical actin cytoskeleton organization and biogenesis [GO:0030866] 0.006946664 -2.69939 post-translational protein modification [GO:0043687] 0.006253946 -2.734161 biopolymer metabolic process [GO:0043283] 0.005971686 -2.749332 organelle fusion [GO:0048284] 0.005690939 -2.765077 single-stranded RNA binding [GO:0003727] 0.005346336 -2.78539 estrogen receptor signaling pathway [GO:0030520] 0.004717814 -2.825695 trans-Golgi network [GO:0005802] 0.004178299 -2.864377 methyltransferase activity [GO:0008168] 0.001550863 -3.164994 transferase activity, transferring one-carbon groups [GO:0016741] 0.001303205 -3.215273 ligase activity [GO:0016874] 0.000652268 -3.408894 macromolecule catabolic process [GO:0009057] 0.000595055 -3.433859 cellular macromolecule catabolic process [GO:0044265] 0.000236012 -3.676979 biopolymer catabolic process [GO:0043285] 0.000153234 -3.785769 ubiquitin ligase complex [GO:0000151] 8.46E-05 -3.931012 protein modification by small protein conjugation [GO:0032446] 3.43E-05 -4.142666 ligase activity, forming carbon-nitrogen bonds [GO:0016879] 3.34E-05 -4.149198 protein ubiquitination [GO:0016567] 2.71E-05 -4.196913 protein catabolic process [GO:0030163] 1.73E-05 -4.297667 ubiquitin-protein ligase activity [GO:0004842] 8.65E-06 -4.448363 cellular protein catabolic process [GO:0044257] 7.06E-06 -4.491847 ubiquitin-dependent protein catabolic process [GO:0006511] 5.26E-06 -4.554052 modification-dependent protein catabolic process [GO:0019941] 5.26E-06 -4.554052 modification-dependent macromolecule catabolic process [GO:0043632] 5.26E-06 -4.554052 proteolysis involved in cellular protein catabolic process [GO:0051603] 5.26E-06 -4.554052 acid-amino acid ligase activity [GO:0016881] 5.19E-06 -4.55695 small conjugating protein ligase activity [GO:0019787] 4.41E-06 -4.591296 ubiquitin cycle [GO:0006512] 4.03E-07 -5.067714