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		Minireview Reconstructing prokaryotic transcriptional regulatory networks: lessons from actinobacteria Thiago M Venancio, L Aravind Journal of Biology 2009, 8:29 (15 April 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Venancio and Aravind review recent studies, including one in BMC Systems Biology, that offer new ways to reconstruct transcriptional regulatory networks in previously uncharacterised prokaryotes, such as the actinobacteria.
		Minireview Genome degeneration affects both extracellular and intracellular bacterial endosymbionts Heike Feldhaar, Roy Gross Journal of Biology 2009, 8:31 (6 April 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Feldhaar and Gross discuss a new study in BMC Biology that suggests extracellular endosymbionts, like obligate intracellular bacteria, lose essential genes and become slaves to their hosts.
		Minireview Distant metastasis: not out of reach any more François Bertucci, Daniel Birnbaum Journal of Biology 2009, 8:28 (27 March 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Bertucci and Birnbaum review gene expression profiles published in BMC Medicine and BMC Cancer on distant cancer metastasis that predict poor outcome, but may help target anti-angiogenesis therapies.
		Minireview Pitfalls in the phylogenomic evaluation of human disease-causing mutations Andrew OM Wilkie Journal of Biology 2009, 8:26 (24 March 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Andrew Wilkie discusses (the pitfalls of) a new phylogenomic study, published in BMC Evolutionary Biology, that has identified conserved sequences in the MSX homeobox family proteins suspected to be involved in human diseases.
		Minireview Liaison amid disorder: non-native interactions may underpin long-range coupling in proteins Hue Chan, Zhuqing Zhang Journal of Biology 2009, 8:27 (13 March 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Chan and Zhang, discussing a study published in BMC Structural Biology, argue that while close contacts between amino acids stabilize protein folds, long-range destablilizing interactions may be important in allowing them to evolve new functions.
		Comment Are we training pit bulls to review our manuscripts? Virginia Walbot Journal of Biology 2009, 8:24 (9 March 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 4 comments \| Editor’s summary Virginia Walbot accepts some of the blame for remorselessly negative reviewers, and suggests a training program for graduate students and post docs that will deliver a fairer assessment of manuscripts.
		Minireview In ovo omnia: diversification by duplication in fish and other vertebrates Ingo Braasch, Walter Salzburger Journal of Biology 2009, 8:25 (5 March 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Ingo Braasch and Walter Salzburger discuss an article published in BMC Evolutionary Biology that suggests how differential evolution of the duplicated vitellogenin yolk protein genes in fish allowed the development of crucial new spawning strategies.
		Editorial The light of evolution Miranda Robertson Journal of Biology 2009, 8:10 (27 February 2009) Full text \| PDF \| PubMed
		Minireview Estimating rates and patterns of morphological evolution from phylogenies: lessons in limb lability from Australian Lerista lizards John J Wiens Journal of Biology 2009, 8:19 (24 February 2009) Abstract \| Full text \| PDF \| PubMed
		Opinion Why didn't Darwin discover Mendel's laws? Jonathan C Howard Journal of Biology 2009, 8:15 (24 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In an opinion piece, Jonathan Howard suggests that Darwin failed to discover the laws of inheritance (Mendel’s laws) due to his focus on small quantitative variations as the raw material of evolution.
		Opinion Darwin and Huxley revisited: the origin of allometry Charles F Stevens Journal of Biology 2009, 8:14 (23 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Charles Stevens argues that evolution respects power laws, and that explains the way that organs scale with the size of the individual- first described by Julian Huxley as "allometry".
		Opinion Mayr, mathematics and the study of evolution James F Crow Journal of Biology 2009, 8:13 (23 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary James Crow picks up the gauntlet thrown down by Mayr at the feet of JBS Haldane, and describes the essential contribution of mathematics to the understanding of evolution from genetic drift to molecular clocks.
		Opinion Evolutionary genomics and the reach of selection Laurence D Hurst Journal of Biology 2009, 8:12 (23 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Laurence Hurst explains how evolutionary genomics, married to an understanding of molecular mechanisms, can show the impact of selection where it is not expected.
		Question & Answer Q&A: What did Charles Darwin prove? Paul Harvey Journal of Biology 2009, 8:11 (23 February 2009) Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Paul Harvey argues that Darwin was an accomplished 21st-century biologist and marvels that in his extensive studies on the inheritance of variation he failed to discover Mendel’s laws.
		Research article Contrast enhancement of stimulus intermittency in a primary olfactory network and its behavioral significance Hong Lei, Jeffrey A Riffell, Stephanie L Gage, John G Hildebrand Journal of Biology 2009, 8:21 (20 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Discrete bursts of activity in the olfactory neurons of moths allow them to track drifting odors, essential for locating pheromone-releasing females.
		Minireview Representations of odor plume flux are accentuated deep within the moth brain Thomas C Baker Journal of Biology 2009, 8:16 (20 February 2009) Abstract \| Full text \| PDF \| PubMed
		Review Apes, lice and prehistory Robin A Weiss Journal of Biology 2009, 8:20 (10 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments \| Editor’s summary In a special issue to celebrate the bicentennial of Darwin's birth, Robin Weiss reviews recent speculations on human prehistory based on louse phylogeny, and adds his own on the origins of pubic hair.
		Minireview Timing the first human migration into eastern Asia Roscoe Stanyon, Marco Sazzini, Donata Luiselli Journal of Biology 2009, 8:18 (6 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments
		Minireview Conserved elements within open reading frames of mammalian Hox genes Joost M Woltering, Denis Duboule Journal of Biology 2009, 8:17 (6 February 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Joost Woltering and Denis Duboule, writing on a paper published in BMC Evolutionary Biology, discuss the increasing evidence for regulatory elements in the coding sequences of genes, and possible explanations of their specialized functions.
		Editorial What are journals for? Miranda Robertson Journal of Biology 2009, 8:1 (27 January 2009) Full text \| PDF \| Editor’s summary Journal of Biology launches a re-review opt-out experiment in response to widespread dissatisfaction with peer review, and publishes the first of two new regular features - a full review on the ribosome and a question-and-answer feature on systems biology.
		Research article A circuit supporting concentration-invariant odor perception in Drosophila Kenta Asahina, Matthieu Louis, Silvia Piccinotti, Leslie B Vosshall Journal of Biology 2009, 8:9 (26 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary In Drosophila, inhibitory interneurons are progressively recruited as olfactory sensory neurons are activated at increasing odor concentrations, allowing the flies to identify distinct odors at different intensities.
		Review The ribosome returned Peter B Moore Journal of Biology 2009, 8:8 (26 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Lateral inhibition and concentration-invariant odor perception Susy M Kim, Jing W Wang Journal of Biology 2009, 8:4 (26 January 2009) Abstract \| Full text \| PDF \| PubMed
		Comment 'Validation' in genome-scale research Timothy R Hughes Journal of Biology 2009, 8:3 (26 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Question & Answer Q&A: Systems biology James E Ferrell Journal of Biology 2009, 8:2 (26 January 2009) Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Happy together: genomic insights into the unique Nanoarchaeum/Ignicoccus association Patrick Forterre, Simonetta Gribaldo, Céline Brochier-Armanet Journal of Biology 2009, 8:7 (23 January 2009) Abstract \| Full text \| PDF \| PubMed
		Minireview Sperm dumping as a defense against meiotic drive Tom Price, Zenobia Lewis, Nina Wedell Journal of Biology 2009, 8:6 (20 January 2009) Abstract \| Full text \| PDF \| PubMed
		Minireview Limb regeneration revisited Jessica L Whited, Clifford J Tabin Journal of Biology 2009, 8:5 (13 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview The future of artemisinins: natural, synthetic or recombinant? Marcel Hommel Journal of Biology 2008, 7:38 (15 December 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Neuronal remodeling on the evolutionary timescale Ithai Rabinowitch, William Schafer Journal of Biology 2008, 7:37 (15 December 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Bridge helix and trigger loop perturbations generate superactive RNA polymerases Lin Tan, Simone Wiesler, Dominika Trzaska, Hannah C Carney, Robert OJ Weinzierl Journal of Biology 2008, 7:40 (2 December 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Mutations targeted to key functional areas of RNA polymerases can generate superactive enzymes that suggest how conformational changes in specialized domains of the enzyme contribute to the catalytic cycle.
		Minireview A bridge to transcription by RNA polymerase Craig D Kaplan, Roger D Kornberg Journal of Biology 2008, 7:39 (2 December 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Obesity genes: so close and yet so far... Daniel Pomp, Karen L Mohlke Journal of Biology 2008, 7:36 (27 November 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Globin genes on the move Ross C Hardison Journal of Biology 2008, 7:35 (20 November 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview RNA interference in nematodes and the chance that favored Sydney Brenner Marie-Anne Félix Journal of Biology 2008, 7:34 (13 November 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Aquaglyceroporins: ancient channels for metalloids Hiranmoy Bhattacharjee, Rita Mukhopadhyay, Saravanamuthu Thiyagarajan, Barry P Rosen Journal of Biology 2008, 7:33 (7 November 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Islands in the sky: the impact of Pleistocene climate cycles on biodiversity Allan J Baker Journal of Biology 2008, 7:32 (3 November 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Guanylyl cyclase sees the light John JG Tesmer Journal of Biology 2008, 7:31 (31 October 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview X-chromosome inactivation: the molecular basis of silencing Barbara Panning Journal of Biology 2008, 7:30 (27 October 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview NFIX – one gene, two knockouts, multiple effects Vladimir Pekarik, Juan Belmonte Journal of Biology 2008, 7:29 (23 October 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Immune function keeps endosymbionts under control Stuart Reynolds, Jens Rolff Journal of Biology 2008, 7:28 (16 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Bridging spinal cord injuries James W Fawcett Journal of Biology 2008, 7:25 (15 October 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Observing bacteria through the lens of social evolution Carey D Nadell, Bonnie L Bassler, Simon A Levin Journal of Biology 2008, 7:27 (30 September 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Will he still look good with the lights on? Spectral tuning of visual pigments in fish Julia C Jones, Helen M Gunter, Axel Meyer Journal of Biology 2008, 7:26 (25 September 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injury Jeannette E Davies, Christoph Pröschel, Ningzhe Zhang, Mark Noble, Margot Mayer-Pröschel, Stephen JA Davies Journal of Biology 2008, 7:24 (19 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Glial cells can promote the repair of damaged spinal cord, but experiments in rats show that while some promote functional recovery others cause abnormal growth and pain, depending on the growth factor used to cultivate them in culture.
		Minireview Appetite for reproduction: dietary restriction, aging and the mammalian gonad Roopa L Nalam, Scott D Pletcher, Martin M Matzuk Journal of Biology 2008, 7:23 (16 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Evolution of virulence in malaria Bridget Penman, Sunetra Gupta Journal of Biology 2008, 7:22 (28 August 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Music, memory and emotion Lutz Jäncke Journal of Biology 2008, 7:21 (8 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Drug-therapy networks and the prediction of novel drug targets Zoltan Spiro, Istvan A Kovacs, Peter Csermely Journal of Biology 2008, 7:20 (31 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Genomics technology for assessing soil pollution Nico M van Straalen, Dick Roelofs Journal of Biology 2008, 7:19 (14 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Stage debut for the elusive Drosophila insulin-like growth factor binding protein Nazif Alic, Linda Partridge Journal of Biology 2008, 7:18 (7 July 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Making the jump: new insights into the mechanism of trans-translation Jacek Wower, Iwona K Wower, Christian Zwieb Journal of Biology 2008, 7:17 (30 June 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Zoological detective stories: the case of the facetotectan crustacean life cycle Gerhard Scholtz Journal of Biology 2008, 7:16 (26 June 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Spatially patterned gradients of synaptic connectivity are established early in the developing retina Susana Cohen-Cory Journal of Biology 2008, 7:15 (9 June 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Process rather than pattern: finding pine needles in the coevolutionary haystack David R Nash Journal of Biology 2008, 7:14 (28 May 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Colugos: obscure mammals glide into the evolutionary limelight Robert D Martin Journal of Biology 2008, 7:13 (1 May 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system Ruolan Han, Yin M Yang, Joerg Dietrich, Anne Luebke, Margot Mayer-Pröschel, Mark Noble Journal of Biology 2008, 7:12 (22 April 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary The chemotherapy drug, 5-fluorouracil, causes delayed degeneration in the central nervous system of animals, a newly identified type of damage that helps explain the cognitive defects or `chemobrain` symptoms associated with cancer treatment.
		Minireview How chemotherapy damages the central nervous system Christina A Meyers Journal of Biology 2008, 7:11 (22 April 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
		Research article Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance Basil Honegger, Milos Galic, Katja Köhler, Franz Wittwer, Walter Brogiolo, Ernst Hafen, Hugo Stocker Journal of Biology 2008, 7:10 (15 April 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The first functional insulin-binding protein identified in invertebrates, Imp-L2, controls Drosophila body size by regulating insulin-mediated growth and is essential for larval survival and dampening insulin signaling under starvation conditions.
		Minireview Small changes, big results: evolution of morphological discontinuity in mammals Rodney L Honeycutt Journal of Biology 2008, 7:9 (18 March 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview A Caenorhabditis elegans genetic-interaction map wiggles into view Kristin C Gunsalus Journal of Biology 2008, 7:8 (7 March 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy? Nicolas Vodovar, François Schweisguth Journal of Biology 2008, 7:7 (28 February 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Reasons for breast cancer heterogeneity François Bertucci, Daniel Birnbaum Journal of Biology 2008, 7:6 (22 February 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Great exaptations Kathleen H Burns, Jef D Boeke Journal of Biology 2008, 7:5 (15 February 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Semaphorins deployed to repel cell migrants at spinal cord borders Sophie Chauvet, Geneviève Rougon Journal of Biology 2008, 7:4 (7 February 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Electrical protein detection in cell lysates using high-density peptide-aptamer microarrays David Evans, Steven Johnson, Sophie Laurenson, A Giles Davies, Paul Ko Ferrigno, Christoph Wälti Journal of Biology 2008, 7:3 (31 January 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Specific detection of protein isoforms in whole cell lysates is now more efficient with the arrival of a label-free electronic sensing system consisting of immobilized peptide aptamers on individual gold electrodes at the micron scale.
		Minireview The eleven-year switch of peptide aptamers Pierre Colas Journal of Biology 2008, 7:2 (31 January 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Metabolic reconfiguration is a regulated response to oxidative stress Chris M Grant Journal of Biology 2008, 7:1 (25 January 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Cryptic biodiversity in a changing world Luciano B Beheregaray, Adalgisa Caccone Journal of Biology 2007, 6:9 (21 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress Markus Ralser, Mirjam M Wamelink, Axel Kowald, Birgit Gerisch, Gino Heeren, Eduard A Struys, Edda Klipp, Cornelis Jakobs, Michael Breitenbach, Hans Lehrach, Sylvia Krobitsch Journal of Biology 2007, 6:10 (21 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary Yeast and C. elegans share a conserved cellular mechanism that counteracts the fatal consequences of oxidative stress by enabling the redirection of metabolic flux from glycolysis to the pentose phosphate pathway.
		Minireview Landscape genetics goes to sea Michael Hansen, Jakob Hemmer-Hansen Journal of Biology 2007, 6:6 (16 November 2007) Abstract \| Full text \| PDF \| PubMed
		Research article A global analysis of genetic interactions in Caenorhabditis elegans Alexandra B Byrne, Matthew T Weirauch, Victoria Wong, Martina Koeva, Scott J Dixon, Joshua M Stuart, Peter J Roy Journal of Biology 2007, 6:8 (26 September 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A C. elegans genetic-interaction network built by combining gene mutants and knockdowns is the largest animal network to date, revealing redundancy among functional modules and surprisingly little conservation of network connections compared to yeast.
		Editorial Journal of Biology celebrates its fifth anniversary Journal of Biology 2007, 6:5 (29 June 2007) Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Growth control of the eukaryote cell: a systems biology study in yeast Juan I Castrillo, Leo A Zeef, David C Hoyle, Nianshu Zhang, Andrew Hayes, David CJ Gardner, Michael J Cornell, June Petty, Luke Hakes, Leanne Wardleworth, Bharat Rash, Marie Brown, Warwick B Dunn, David Broadhurst, Kerry O'Donoghue, Svenja S Hester, Tom PJ Dunkley, Sarah R Hart, Neil Swainston, Peter Li, Simon J Gaskell, Norman W Paton, Kathryn S Lilley, Douglas B Kell, Stephen G Oliver Journal of Biology 2007, 6:4 (30 April 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary The first comprehensive systems biology study on growth rate control in yeast integrates information from the transcriptome, proteome and metabolome to reveal how cell growth underlies key cellular and development processes.
		Minireview Multilevel regulation of growth rate in yeast revealed using systems biology Arvind Ramanathan, Stuart L Schreiber Journal of Biology 2007, 6:3 (30 April 2007) Abstract \| Full text \| PDF \| PubMed
		Research article Dosage compensation is less effective in birds than in mammals Yuichiro Itoh, Esther Melamed, Xia Yang, Kathy Kampf, Susanna Wang, Nadir Yehya, Atila Van Nas, Kirstin Replogle, Mark R Band, David F Clayton, Eric E Schadt, Aldons J Lusis, Arthur P Arnold Journal of Biology 2007, 6:2 (22 March 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Male:female ratios of gene expression in zebra finch and chicken reveal that birds, unlike mammals, have surprisingly ineffective sex-chromosome dosage compensation mechanisms resulting in an imbalance between autosomal and sex-linked genes.
		Minireview Does gene dosage really matter? Jennifer Graves, Christine M Disteche Journal of Biology 2007, 6:1 (22 March 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo Joerg Dietrich, Ruolan Han, Yin Yang, Margot Mayer-Pröschel, Mark Noble Journal of Biology 2006, 5:22 (30 November 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Chemotherapeutic agents are more toxic to cells of the central nervous system than to cancer cells when administered to mice and cultured cells, providing an explanation for adverse neurological effects of systemic chemotherapy.
		Minireview The long term effects of chemotherapy on the central nervous system Patricia K Duffner Journal of Biology 2006, 5:21 (30 November 2006) Abstract \| Full text \| PDF \| PubMed
		Research article High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry Claude Lechene, Francois Hillion, Greg McMahon, Douglas Benson, Alan M Kleinfeld, J Patrick Kampf, Daniel Distel, Yvette Luyten, Joseph Bonventre, Dirk Hentschel, Kwon Park, Susumu Ito, Martin Schwartz, Gilles Benichou, Georges Slodzian Journal of Biology 2006, 5:20 (5 October 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary For the first time it is possible to image and quantify at nanometer resolution biological samples labeled with stable isotopes, using multi-isotope imaging mass spectrometry, applicable to all fields of biomedical research.
		Minireview Biological imaging using secondary ions Peter Williams Journal of Biology 2006, 5:18 (5 October 2006) Abstract \| Full text \| PDF \| PubMed
		Research news Imaging with isotopes: high resolution and quantitation Jonathan B Weitzman Journal of Biology 2006, 5:17 (5 October 2006) Full text \| PDF
		Research article A quantitative analysis of the mechanism that controls body size in Manduca sexta HF Nijhout, G Davidowitz, DA Roff Journal of Biology 2006, 5:16 (2 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Final body size in the moth Manduca sexta can be predicted from the juvenile caterpillar by modeling three key growth measurements to reveal how growth rate, nutrition and temperature determine eventual body size.
		Minireview The proximate determinants of insect size Joseph Parker, Laura A Johnston Journal of Biology 2006, 5:15 (2 August 2006) Abstract \| Full text \| PDF \| PubMed
		Minireview Distinct functions for ERKs? Alison C Lloyd Journal of Biology 2006, 5:13 (19 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
		Comment Dimerization in protein kinase signaling Steven Pelech Journal of Biology 2006, 5:12 (19 July 2006) Abstract \| Full text \| PDF \| PubMed
		Research article ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially Chiara Vantaggiato, Ivan Formentini, Attilio Bondanza, Chiara Bonini, Luigi Naldini, Riccardo Brambilla Journal of Biology 2006, 5:14 (28 June 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The mitogen-activated protein kinases ERK1 and ERK2 have unexpectedly independent roles in normal and malignant Ras-dependent cell proliferation; ERK2 controls normal cell proliferation whereas ERK1 antagonizes ERK2 activity.
		Research article Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae Teresa Reguly, Ashton Breitkreutz, Lorrie Boucher, Bobby-Joe Breitkreutz, Gary C Hon, Chad L Myers, Ainslie Parsons, Helena Friesen, Rose Oughtred, Amy Tong, Chris Stark, Yuen Ho, David Botstein, Brenda Andrews, Charles Boone, Olga G Troyanskya, Trey Ideker, Kara Dolinski, Nizar N Batada, Mike Tyers Journal of Biology 2006, 5:11 (8 June 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A new literature-based yeast database documents over 33,000 biological interactions, manually curated from the primary literature, and provides an invaluable resource to benchmark high-throughput methods in the study of complex networks.
		Minireview The interaction map of yeast: terra incognita? Joe Mellor, Charles DeLisi Journal of Biology 2006, 5:10 (8 June 2006) Abstract \| Full text \| PDF \| PubMed
		Research article The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans Cheng-Wen Su, Suzanne Tharin, Yishi Jin, Bruce Wightman, Mona Spector, David Meili, Nancy Tsung, Christa Rhiner, Dimitris Bourikas, Esther Stoeckli, Gian Garriga, H Robert Horvitz, Michael O Hengartner Journal of Biology 2006, 5:9 (25 May 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Newly characterized in C. elegans, the protein UNC-69 interacts with kinesin–binding protein UNC-76 in a complex associated with trafficking vesicles along axons - a process that drives axon growth and helps synapse formation.
		Minireview Regulators of kinesin involved in polarized trafficking and axon outgrowth Shuo Luo, Michael L Nonet Journal of Biology 2006, 5:8 (25 May 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Building bridges with astrocytes for spinal cord repair Robert H Miller Journal of Biology 2006, 5:6 (9 May 2006) Abstract \| Full text \| PDF \| PubMed
		Research article Astrocytes derived from glial-restricted precursors promote spinal cord repair Jeannette E Davies, Carol Huang, Christoph Proschel, Mark Noble, Margot Mayer-Proschel, Stephen JA Davies Journal of Biology 2006, 5:7 (27 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Significantly better spinal cord repair in rats results from transplanting specific pre-differentiated cells, cultured to become immature neural-support cells, than from transplanting undifferentiated embryonic stem cells.
		Research article Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function Owain R Millington, Caterina Di Lorenzo, R Phillips, Paul Garside, James M Brewer Journal of Biology 2006, 5:5 (12 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Hemozoin pigment, released during malarial infection, is now known to cause dendritic cell failure and subsequent host immunosupression, explaining why people with malaria become prone to infection and respond poorly to vaccines.
		Minireview Malaria pigment paralyzes dendritic cells Britta C Urban, Stephen Todryk Journal of Biology 2006, 5:4 (12 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Global analysis of X-chromosome dosage compensation Vaijayanti Gupta, Michael Parisi, David Sturgill, Rachel Nuttall, Michael Doctolero, Olga K Dudko, James D Malley, P Scott Eastman, Brian Oliver Journal of Biology 2006, 5:3 (16 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary In Drosophila germ cells, X chromosome genes are upregulated to balance their expression with that of autosomes; the same happens in somatic cells of mice and nematodes.
		Minireview A balancing act between the X chromosome and the autosomes Mimi K Cheng, Christine M Disteche Journal of Biology 2006, 5:2 (16 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research news Getting the right dose of sex (chromosomes) Jonathan B Weitzman Journal of Biology 2006, 5:1 (16 February 2006) Abstract \| Full text \| PDF
		Minireview Recycling signals in the neural crest Lisa A Taneyhill, Marianne Bronner-Fraser Journal of Biology 2006, 4:10 (9 January 2006) Abstract \| Full text \| PDF
		Research article Compound developmental eye disorders following inactivation of TGFβ signaling in neural-crest stem cells Lars M Ittner, Heiko Wurdak, Kerstin Schwerdtfeger, Thomas Kunz, Fabian Ille, Per Leveen, Tord A Hjalt, Ueli Suter, Stefan Karlsson, Farhad Hafezi, Walter Born, Lukas Sommer Journal of Biology 2005, 4:11 (14 December 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Important structures in developing mouse eyes originate from neural crest cells controlled by TGFbeta signals from the lens, providing insight into human conditions that results in glaucoma and blindness.

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		Minireview Reconstructing prokaryotic transcriptional regulatory networks: lessons from actinobacteria Thiago M Venancio, L Aravind Journal of Biology 2009, 8:29 (15 April 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Venancio and Aravind review recent studies, including one in BMC Systems Biology, that offer new ways to reconstruct transcriptional regulatory networks in previously uncharacterised prokaryotes, such as the actinobacteria.
		Minireview Genome degeneration affects both extracellular and intracellular bacterial endosymbionts Heike Feldhaar, Roy Gross Journal of Biology 2009, 8:31 (6 April 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Feldhaar and Gross discuss a new study in BMC Biology that suggests extracellular endosymbionts, like obligate intracellular bacteria, lose essential genes and become slaves to their hosts.
		Minireview Distant metastasis: not out of reach any more François Bertucci, Daniel Birnbaum Journal of Biology 2009, 8:28 (27 March 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Bertucci and Birnbaum review gene expression profiles published in BMC Medicine and BMC Cancer on distant cancer metastasis that predict poor outcome, but may help target anti-angiogenesis therapies.
		Minireview Pitfalls in the phylogenomic evaluation of human disease-causing mutations Andrew OM Wilkie Journal of Biology 2009, 8:26 (24 March 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Andrew Wilkie discusses (the pitfalls of) a new phylogenomic study, published in BMC Evolutionary Biology, that has identified conserved sequences in the MSX homeobox family proteins suspected to be involved in human diseases.
		Minireview Liaison amid disorder: non-native interactions may underpin long-range coupling in proteins Hue Chan, Zhuqing Zhang Journal of Biology 2009, 8:27 (13 March 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Chan and Zhang, discussing a study published in BMC Structural Biology, argue that while close contacts between amino acids stabilize protein folds, long-range destablilizing interactions may be important in allowing them to evolve new functions.
		Comment Are we training pit bulls to review our manuscripts? Virginia Walbot Journal of Biology 2009, 8:24 (9 March 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 4 comments \| Editor’s summary Virginia Walbot accepts some of the blame for remorselessly negative reviewers, and suggests a training program for graduate students and post docs that will deliver a fairer assessment of manuscripts.
		Minireview In ovo omnia: diversification by duplication in fish and other vertebrates Ingo Braasch, Walter Salzburger Journal of Biology 2009, 8:25 (5 March 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Ingo Braasch and Walter Salzburger discuss an article published in BMC Evolutionary Biology that suggests how differential evolution of the duplicated vitellogenin yolk protein genes in fish allowed the development of crucial new spawning strategies.
		Editorial The light of evolution Miranda Robertson Journal of Biology 2009, 8:10 (27 February 2009) Full text \| PDF \| PubMed
		Minireview Estimating rates and patterns of morphological evolution from phylogenies: lessons in limb lability from Australian Lerista lizards John J Wiens Journal of Biology 2009, 8:19 (24 February 2009) Abstract \| Full text \| PDF \| PubMed
		Opinion Why didn't Darwin discover Mendel's laws? Jonathan C Howard Journal of Biology 2009, 8:15 (24 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In an opinion piece, Jonathan Howard suggests that Darwin failed to discover the laws of inheritance (Mendel’s laws) due to his focus on small quantitative variations as the raw material of evolution.
		Opinion Darwin and Huxley revisited: the origin of allometry Charles F Stevens Journal of Biology 2009, 8:14 (23 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Charles Stevens argues that evolution respects power laws, and that explains the way that organs scale with the size of the individual- first described by Julian Huxley as "allometry".
		Opinion Mayr, mathematics and the study of evolution James F Crow Journal of Biology 2009, 8:13 (23 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary James Crow picks up the gauntlet thrown down by Mayr at the feet of JBS Haldane, and describes the essential contribution of mathematics to the understanding of evolution from genetic drift to molecular clocks.
		Opinion Evolutionary genomics and the reach of selection Laurence D Hurst Journal of Biology 2009, 8:12 (23 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Laurence Hurst explains how evolutionary genomics, married to an understanding of molecular mechanisms, can show the impact of selection where it is not expected.
		Question & Answer Q&A: What did Charles Darwin prove? Paul Harvey Journal of Biology 2009, 8:11 (23 February 2009) Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Paul Harvey argues that Darwin was an accomplished 21st-century biologist and marvels that in his extensive studies on the inheritance of variation he failed to discover Mendel’s laws.
		Research article Contrast enhancement of stimulus intermittency in a primary olfactory network and its behavioral significance Hong Lei, Jeffrey A Riffell, Stephanie L Gage, John G Hildebrand Journal of Biology 2009, 8:21 (20 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Discrete bursts of activity in the olfactory neurons of moths allow them to track drifting odors, essential for locating pheromone-releasing females.
		Minireview Representations of odor plume flux are accentuated deep within the moth brain Thomas C Baker Journal of Biology 2009, 8:16 (20 February 2009) Abstract \| Full text \| PDF \| PubMed
		Review Apes, lice and prehistory Robin A Weiss Journal of Biology 2009, 8:20 (10 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments \| Editor’s summary In a special issue to celebrate the bicentennial of Darwin's birth, Robin Weiss reviews recent speculations on human prehistory based on louse phylogeny, and adds his own on the origins of pubic hair.
		Minireview Timing the first human migration into eastern Asia Roscoe Stanyon, Marco Sazzini, Donata Luiselli Journal of Biology 2009, 8:18 (6 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments
		Minireview Conserved elements within open reading frames of mammalian Hox genes Joost M Woltering, Denis Duboule Journal of Biology 2009, 8:17 (6 February 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Joost Woltering and Denis Duboule, writing on a paper published in BMC Evolutionary Biology, discuss the increasing evidence for regulatory elements in the coding sequences of genes, and possible explanations of their specialized functions.
		Editorial What are journals for? Miranda Robertson Journal of Biology 2009, 8:1 (27 January 2009) Full text \| PDF \| Editor’s summary Journal of Biology launches a re-review opt-out experiment in response to widespread dissatisfaction with peer review, and publishes the first of two new regular features - a full review on the ribosome and a question-and-answer feature on systems biology.
		Research article A circuit supporting concentration-invariant odor perception in Drosophila Kenta Asahina, Matthieu Louis, Silvia Piccinotti, Leslie B Vosshall Journal of Biology 2009, 8:9 (26 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary In Drosophila, inhibitory interneurons are progressively recruited as olfactory sensory neurons are activated at increasing odor concentrations, allowing the flies to identify distinct odors at different intensities.
		Review The ribosome returned Peter B Moore Journal of Biology 2009, 8:8 (26 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Lateral inhibition and concentration-invariant odor perception Susy M Kim, Jing W Wang Journal of Biology 2009, 8:4 (26 January 2009) Abstract \| Full text \| PDF \| PubMed
		Comment 'Validation' in genome-scale research Timothy R Hughes Journal of Biology 2009, 8:3 (26 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Question & Answer Q&A: Systems biology James E Ferrell Journal of Biology 2009, 8:2 (26 January 2009) Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Happy together: genomic insights into the unique Nanoarchaeum/Ignicoccus association Patrick Forterre, Simonetta Gribaldo, Céline Brochier-Armanet Journal of Biology 2009, 8:7 (23 January 2009) Abstract \| Full text \| PDF \| PubMed
		Minireview Sperm dumping as a defense against meiotic drive Tom Price, Zenobia Lewis, Nina Wedell Journal of Biology 2009, 8:6 (20 January 2009) Abstract \| Full text \| PDF \| PubMed
		Minireview Limb regeneration revisited Jessica L Whited, Clifford J Tabin Journal of Biology 2009, 8:5 (13 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview The future of artemisinins: natural, synthetic or recombinant? Marcel Hommel Journal of Biology 2008, 7:38 (15 December 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Neuronal remodeling on the evolutionary timescale Ithai Rabinowitch, William Schafer Journal of Biology 2008, 7:37 (15 December 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Bridge helix and trigger loop perturbations generate superactive RNA polymerases Lin Tan, Simone Wiesler, Dominika Trzaska, Hannah C Carney, Robert OJ Weinzierl Journal of Biology 2008, 7:40 (2 December 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Mutations targeted to key functional areas of RNA polymerases can generate superactive enzymes that suggest how conformational changes in specialized domains of the enzyme contribute to the catalytic cycle.
		Minireview A bridge to transcription by RNA polymerase Craig D Kaplan, Roger D Kornberg Journal of Biology 2008, 7:39 (2 December 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Obesity genes: so close and yet so far... Daniel Pomp, Karen L Mohlke Journal of Biology 2008, 7:36 (27 November 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Globin genes on the move Ross C Hardison Journal of Biology 2008, 7:35 (20 November 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview RNA interference in nematodes and the chance that favored Sydney Brenner Marie-Anne Félix Journal of Biology 2008, 7:34 (13 November 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Aquaglyceroporins: ancient channels for metalloids Hiranmoy Bhattacharjee, Rita Mukhopadhyay, Saravanamuthu Thiyagarajan, Barry P Rosen Journal of Biology 2008, 7:33 (7 November 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Islands in the sky: the impact of Pleistocene climate cycles on biodiversity Allan J Baker Journal of Biology 2008, 7:32 (3 November 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Guanylyl cyclase sees the light John JG Tesmer Journal of Biology 2008, 7:31 (31 October 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview X-chromosome inactivation: the molecular basis of silencing Barbara Panning Journal of Biology 2008, 7:30 (27 October 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview NFIX – one gene, two knockouts, multiple effects Vladimir Pekarik, Juan Belmonte Journal of Biology 2008, 7:29 (23 October 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Immune function keeps endosymbionts under control Stuart Reynolds, Jens Rolff Journal of Biology 2008, 7:28 (16 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Bridging spinal cord injuries James W Fawcett Journal of Biology 2008, 7:25 (15 October 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Observing bacteria through the lens of social evolution Carey D Nadell, Bonnie L Bassler, Simon A Levin Journal of Biology 2008, 7:27 (30 September 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Will he still look good with the lights on? Spectral tuning of visual pigments in fish Julia C Jones, Helen M Gunter, Axel Meyer Journal of Biology 2008, 7:26 (25 September 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injury Jeannette E Davies, Christoph Pröschel, Ningzhe Zhang, Mark Noble, Margot Mayer-Pröschel, Stephen JA Davies Journal of Biology 2008, 7:24 (19 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Glial cells can promote the repair of damaged spinal cord, but experiments in rats show that while some promote functional recovery others cause abnormal growth and pain, depending on the growth factor used to cultivate them in culture.
		Minireview Appetite for reproduction: dietary restriction, aging and the mammalian gonad Roopa L Nalam, Scott D Pletcher, Martin M Matzuk Journal of Biology 2008, 7:23 (16 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Evolution of virulence in malaria Bridget Penman, Sunetra Gupta Journal of Biology 2008, 7:22 (28 August 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Music, memory and emotion Lutz Jäncke Journal of Biology 2008, 7:21 (8 August 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Drug-therapy networks and the prediction of novel drug targets Zoltan Spiro, Istvan A Kovacs, Peter Csermely Journal of Biology 2008, 7:20 (31 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Genomics technology for assessing soil pollution Nico M van Straalen, Dick Roelofs Journal of Biology 2008, 7:19 (14 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Stage debut for the elusive Drosophila insulin-like growth factor binding protein Nazif Alic, Linda Partridge Journal of Biology 2008, 7:18 (7 July 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Making the jump: new insights into the mechanism of trans-translation Jacek Wower, Iwona K Wower, Christian Zwieb Journal of Biology 2008, 7:17 (30 June 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Zoological detective stories: the case of the facetotectan crustacean life cycle Gerhard Scholtz Journal of Biology 2008, 7:16 (26 June 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Spatially patterned gradients of synaptic connectivity are established early in the developing retina Susana Cohen-Cory Journal of Biology 2008, 7:15 (9 June 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Process rather than pattern: finding pine needles in the coevolutionary haystack David R Nash Journal of Biology 2008, 7:14 (28 May 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Colugos: obscure mammals glide into the evolutionary limelight Robert D Martin Journal of Biology 2008, 7:13 (1 May 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system Ruolan Han, Yin M Yang, Joerg Dietrich, Anne Luebke, Margot Mayer-Pröschel, Mark Noble Journal of Biology 2008, 7:12 (22 April 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary The chemotherapy drug, 5-fluorouracil, causes delayed degeneration in the central nervous system of animals, a newly identified type of damage that helps explain the cognitive defects or `chemobrain` symptoms associated with cancer treatment.
		Minireview How chemotherapy damages the central nervous system Christina A Meyers Journal of Biology 2008, 7:11 (22 April 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
		Research article Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance Basil Honegger, Milos Galic, Katja Köhler, Franz Wittwer, Walter Brogiolo, Ernst Hafen, Hugo Stocker Journal of Biology 2008, 7:10 (15 April 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The first functional insulin-binding protein identified in invertebrates, Imp-L2, controls Drosophila body size by regulating insulin-mediated growth and is essential for larval survival and dampening insulin signaling under starvation conditions.
		Minireview Small changes, big results: evolution of morphological discontinuity in mammals Rodney L Honeycutt Journal of Biology 2008, 7:9 (18 March 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview A Caenorhabditis elegans genetic-interaction map wiggles into view Kristin C Gunsalus Journal of Biology 2008, 7:8 (7 March 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy? Nicolas Vodovar, François Schweisguth Journal of Biology 2008, 7:7 (28 February 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Reasons for breast cancer heterogeneity François Bertucci, Daniel Birnbaum Journal of Biology 2008, 7:6 (22 February 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Great exaptations Kathleen H Burns, Jef D Boeke Journal of Biology 2008, 7:5 (15 February 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Semaphorins deployed to repel cell migrants at spinal cord borders Sophie Chauvet, Geneviève Rougon Journal of Biology 2008, 7:4 (7 February 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Electrical protein detection in cell lysates using high-density peptide-aptamer microarrays David Evans, Steven Johnson, Sophie Laurenson, A Giles Davies, Paul Ko Ferrigno, Christoph Wälti Journal of Biology 2008, 7:3 (31 January 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Specific detection of protein isoforms in whole cell lysates is now more efficient with the arrival of a label-free electronic sensing system consisting of immobilized peptide aptamers on individual gold electrodes at the micron scale.
		Minireview The eleven-year switch of peptide aptamers Pierre Colas Journal of Biology 2008, 7:2 (31 January 2008) Abstract \| Full text \| PDF \| PubMed
		Minireview Metabolic reconfiguration is a regulated response to oxidative stress Chris M Grant Journal of Biology 2008, 7:1 (25 January 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Cryptic biodiversity in a changing world Luciano B Beheregaray, Adalgisa Caccone Journal of Biology 2007, 6:9 (21 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress Markus Ralser, Mirjam M Wamelink, Axel Kowald, Birgit Gerisch, Gino Heeren, Eduard A Struys, Edda Klipp, Cornelis Jakobs, Michael Breitenbach, Hans Lehrach, Sylvia Krobitsch Journal of Biology 2007, 6:10 (21 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary Yeast and C. elegans share a conserved cellular mechanism that counteracts the fatal consequences of oxidative stress by enabling the redirection of metabolic flux from glycolysis to the pentose phosphate pathway.
		Minireview Landscape genetics goes to sea Michael Hansen, Jakob Hemmer-Hansen Journal of Biology 2007, 6:6 (16 November 2007) Abstract \| Full text \| PDF \| PubMed
		Research article A global analysis of genetic interactions in Caenorhabditis elegans Alexandra B Byrne, Matthew T Weirauch, Victoria Wong, Martina Koeva, Scott J Dixon, Joshua M Stuart, Peter J Roy Journal of Biology 2007, 6:8 (26 September 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A C. elegans genetic-interaction network built by combining gene mutants and knockdowns is the largest animal network to date, revealing redundancy among functional modules and surprisingly little conservation of network connections compared to yeast.
		Editorial Journal of Biology celebrates its fifth anniversary Journal of Biology 2007, 6:5 (29 June 2007) Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Growth control of the eukaryote cell: a systems biology study in yeast Juan I Castrillo, Leo A Zeef, David C Hoyle, Nianshu Zhang, Andrew Hayes, David CJ Gardner, Michael J Cornell, June Petty, Luke Hakes, Leanne Wardleworth, Bharat Rash, Marie Brown, Warwick B Dunn, David Broadhurst, Kerry O'Donoghue, Svenja S Hester, Tom PJ Dunkley, Sarah R Hart, Neil Swainston, Peter Li, Simon J Gaskell, Norman W Paton, Kathryn S Lilley, Douglas B Kell, Stephen G Oliver Journal of Biology 2007, 6:4 (30 April 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary The first comprehensive systems biology study on growth rate control in yeast integrates information from the transcriptome, proteome and metabolome to reveal how cell growth underlies key cellular and development processes.
		Minireview Multilevel regulation of growth rate in yeast revealed using systems biology Arvind Ramanathan, Stuart L Schreiber Journal of Biology 2007, 6:3 (30 April 2007) Abstract \| Full text \| PDF \| PubMed
		Research article Dosage compensation is less effective in birds than in mammals Yuichiro Itoh, Esther Melamed, Xia Yang, Kathy Kampf, Susanna Wang, Nadir Yehya, Atila Van Nas, Kirstin Replogle, Mark R Band, David F Clayton, Eric E Schadt, Aldons J Lusis, Arthur P Arnold Journal of Biology 2007, 6:2 (22 March 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Male:female ratios of gene expression in zebra finch and chicken reveal that birds, unlike mammals, have surprisingly ineffective sex-chromosome dosage compensation mechanisms resulting in an imbalance between autosomal and sex-linked genes.
		Minireview Does gene dosage really matter? Jennifer Graves, Christine M Disteche Journal of Biology 2007, 6:1 (22 March 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo Joerg Dietrich, Ruolan Han, Yin Yang, Margot Mayer-Pröschel, Mark Noble Journal of Biology 2006, 5:22 (30 November 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Chemotherapeutic agents are more toxic to cells of the central nervous system than to cancer cells when administered to mice and cultured cells, providing an explanation for adverse neurological effects of systemic chemotherapy.
		Minireview The long term effects of chemotherapy on the central nervous system Patricia K Duffner Journal of Biology 2006, 5:21 (30 November 2006) Abstract \| Full text \| PDF \| PubMed
		Research article High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry Claude Lechene, Francois Hillion, Greg McMahon, Douglas Benson, Alan M Kleinfeld, J Patrick Kampf, Daniel Distel, Yvette Luyten, Joseph Bonventre, Dirk Hentschel, Kwon Park, Susumu Ito, Martin Schwartz, Gilles Benichou, Georges Slodzian Journal of Biology 2006, 5:20 (5 October 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary For the first time it is possible to image and quantify at nanometer resolution biological samples labeled with stable isotopes, using multi-isotope imaging mass spectrometry, applicable to all fields of biomedical research.
		Minireview Biological imaging using secondary ions Peter Williams Journal of Biology 2006, 5:18 (5 October 2006) Abstract \| Full text \| PDF \| PubMed
		Research news Imaging with isotopes: high resolution and quantitation Jonathan B Weitzman Journal of Biology 2006, 5:17 (5 October 2006) Full text \| PDF
		Research article A quantitative analysis of the mechanism that controls body size in Manduca sexta HF Nijhout, G Davidowitz, DA Roff Journal of Biology 2006, 5:16 (2 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Final body size in the moth Manduca sexta can be predicted from the juvenile caterpillar by modeling three key growth measurements to reveal how growth rate, nutrition and temperature determine eventual body size.
		Minireview The proximate determinants of insect size Joseph Parker, Laura A Johnston Journal of Biology 2006, 5:15 (2 August 2006) Abstract \| Full text \| PDF \| PubMed
		Minireview Distinct functions for ERKs? Alison C Lloyd Journal of Biology 2006, 5:13 (19 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
		Comment Dimerization in protein kinase signaling Steven Pelech Journal of Biology 2006, 5:12 (19 July 2006) Abstract \| Full text \| PDF \| PubMed
		Research article ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially Chiara Vantaggiato, Ivan Formentini, Attilio Bondanza, Chiara Bonini, Luigi Naldini, Riccardo Brambilla Journal of Biology 2006, 5:14 (28 June 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The mitogen-activated protein kinases ERK1 and ERK2 have unexpectedly independent roles in normal and malignant Ras-dependent cell proliferation; ERK2 controls normal cell proliferation whereas ERK1 antagonizes ERK2 activity.
		Research article Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae Teresa Reguly, Ashton Breitkreutz, Lorrie Boucher, Bobby-Joe Breitkreutz, Gary C Hon, Chad L Myers, Ainslie Parsons, Helena Friesen, Rose Oughtred, Amy Tong, Chris Stark, Yuen Ho, David Botstein, Brenda Andrews, Charles Boone, Olga G Troyanskya, Trey Ideker, Kara Dolinski, Nizar N Batada, Mike Tyers Journal of Biology 2006, 5:11 (8 June 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A new literature-based yeast database documents over 33,000 biological interactions, manually curated from the primary literature, and provides an invaluable resource to benchmark high-throughput methods in the study of complex networks.
		Minireview The interaction map of yeast: terra incognita? Joe Mellor, Charles DeLisi Journal of Biology 2006, 5:10 (8 June 2006) Abstract \| Full text \| PDF \| PubMed
		Research article The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans Cheng-Wen Su, Suzanne Tharin, Yishi Jin, Bruce Wightman, Mona Spector, David Meili, Nancy Tsung, Christa Rhiner, Dimitris Bourikas, Esther Stoeckli, Gian Garriga, H Robert Horvitz, Michael O Hengartner Journal of Biology 2006, 5:9 (25 May 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Newly characterized in C. elegans, the protein UNC-69 interacts with kinesin–binding protein UNC-76 in a complex associated with trafficking vesicles along axons - a process that drives axon growth and helps synapse formation.
		Minireview Regulators of kinesin involved in polarized trafficking and axon outgrowth Shuo Luo, Michael L Nonet Journal of Biology 2006, 5:8 (25 May 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Minireview Building bridges with astrocytes for spinal cord repair Robert H Miller Journal of Biology 2006, 5:6 (9 May 2006) Abstract \| Full text \| PDF \| PubMed
		Research article Astrocytes derived from glial-restricted precursors promote spinal cord repair Jeannette E Davies, Carol Huang, Christoph Proschel, Mark Noble, Margot Mayer-Proschel, Stephen JA Davies Journal of Biology 2006, 5:7 (27 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Significantly better spinal cord repair in rats results from transplanting specific pre-differentiated cells, cultured to become immature neural-support cells, than from transplanting undifferentiated embryonic stem cells.
		Research article Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function Owain R Millington, Caterina Di Lorenzo, R Phillips, Paul Garside, James M Brewer Journal of Biology 2006, 5:5 (12 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Hemozoin pigment, released during malarial infection, is now known to cause dendritic cell failure and subsequent host immunosupression, explaining why people with malaria become prone to infection and respond poorly to vaccines.
		Minireview Malaria pigment paralyzes dendritic cells Britta C Urban, Stephen Todryk Journal of Biology 2006, 5:4 (12 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Global analysis of X-chromosome dosage compensation Vaijayanti Gupta, Michael Parisi, David Sturgill, Rachel Nuttall, Michael Doctolero, Olga K Dudko, James D Malley, P Scott Eastman, Brian Oliver Journal of Biology 2006, 5:3 (16 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary In Drosophila germ cells, X chromosome genes are upregulated to balance their expression with that of autosomes; the same happens in somatic cells of mice and nematodes.
		Minireview A balancing act between the X chromosome and the autosomes Mimi K Cheng, Christine M Disteche Journal of Biology 2006, 5:2 (16 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research news Getting the right dose of sex (chromosomes) Jonathan B Weitzman Journal of Biology 2006, 5:1 (16 February 2006) Abstract \| Full text \| PDF
		Minireview Recycling signals in the neural crest Lisa A Taneyhill, Marianne Bronner-Fraser Journal of Biology 2006, 4:10 (9 January 2006) Abstract \| Full text \| PDF
		Research article Compound developmental eye disorders following inactivation of TGFβ signaling in neural-crest stem cells Lars M Ittner, Heiko Wurdak, Kerstin Schwerdtfeger, Thomas Kunz, Fabian Ille, Per Leveen, Tord A Hjalt, Ueli Suter, Stefan Karlsson, Farhad Hafezi, Walter Born, Lukas Sommer Journal of Biology 2005, 4:11 (14 December 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Important structures in developing mouse eyes originate from neural crest cells controlled by TGFbeta signals from the lens, providing insight into human conditions that results in glaucoma and blindness.