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1.

67136
Accesses

Research article   Open Access Highly Accessed

Compound developmental eye disorders following inactivation of TGFβ signaling in neural-crest stem cells

Lars M Ittner, Heiko Wurdak, Kerstin Schwerdtfeger, Thomas Kunz, Fabian Ille, Per Leveen, Tord A Hjalt, Ueli Suter, Stefan Karlsson, Farhad Hafezi, Walter Born, Lukas Sommer Journal of Biology 2005, 4:11 (14 December 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Important structures in developing mouse eyes originate from neural crest cells controlled by TGFbeta signals from the lens, providing insight into human conditions that results in glaucoma and blindness.

2.

57511
Accesses

Research article   Open Access Highly Accessed

A functional genomic analysis of cell morphology using RNA interference

AA Kiger, B Baum, S Jones, MR Jones, A Coulson, C Echeverri, N Perrimon Journal of Biology 2003, 2:27 (1 October 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

3.

46873
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Comment   Free Highly Accessed

Are we training pit bulls to review our manuscripts?

Virginia Walbot Journal of Biology 2009, 8:24 (9 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 4 comments |  Editor’s summary

Virginia Walbot accepts some of the blame for remorselessly negative reviewers, and suggests a training program for graduate students and post docs that will deliver a fairer assessment of manuscripts.

4.

46726
Accesses

Research article   Open Access Highly Accessed

The Drosophila Forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling

Martin A Jünger, Felix Rintelen, Hugo Stocker, Jonathan D Wasserman, Mátyás Végh, Thomas Radimerski, Michael E Greenberg, Ernst Hafen Journal of Biology 2003, 2:20 (7 August 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

5.

44620
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Comment   Free Highly Accessed

Open access to the scientific journal literature

Peter Suber Journal of Biology 2002, 1:3 (18 June 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

6.

44007
Accesses

Research article   Open Access Highly Accessed

The functional landscape of mouse gene expression

Wen Zhang, Quaid D Morris, Richard Chang, Ofer Shai, Malina A Bakowski, Nicholas Mitsakakis, Naveed Mohammad, Mark D Robinson, Ralph Zirngibl, Eszter Somogyi, Nancy Laurin, Eftekhar Eftekharpour, Eric Sat, Jörg Grigull, Qun Pan, Wen-Tao Peng, Nevan Krogan, Jack Greenblatt, Michael Fehlings, Derek van der Kooy, Jane Aubin, Benoit G Bruneau, Janet Rossant, Benjamin J Blencowe, Brendan J Frey, Timothy R Hughes Journal of Biology 2004, 3:21 (6 December 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Gene function in mammals can be quickly and reliably predicted using a quantitative analysis of tissue-specific patterns of RNA expression.

7.

41108
Accesses

Research article   Open Access Highly Accessed

Growth control of the eukaryote cell: a systems biology study in yeast

Juan I Castrillo, Leo A Zeef, David C Hoyle, Nianshu Zhang, Andrew Hayes, David CJ Gardner, Michael J Cornell, June Petty, Luke Hakes, Leanne Wardleworth, Bharat Rash, Marie Brown, Warwick B Dunn, David Broadhurst, Kerry O'Donoghue, Svenja S Hester, Tom PJ Dunkley, Sarah R Hart, Neil Swainston, Peter Li, Simon J Gaskell, Norman W Paton, Kathryn S Lilley, Douglas B Kell, Stephen G Oliver Journal of Biology 2007, 6:4 (30 April 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

The first comprehensive systems biology study on growth rate control in yeast integrates information from the transcriptome, proteome and metabolome to reveal how cell growth underlies key cellular and development processes.

8.

40017
Accesses

Research article   Open Access Highly Accessed

The hydrodynamics of dolphin drafting

Daniel Weihs Journal of Biology 2004, 3:8 (4 May 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Models of the hydrodynamic forces between two swimming dolphins show that baby dolphins keep up with their more powerful mothers by getting an almost energetically "free ride" in their slipstream.

9.

37363
Accesses

Research article   Open Access Highly Accessed

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

Maria Frank-Kamenetsky, Xiaoyan M Zhang, Steve Bottega, Oivin Guicherit, Hynek Wichterle, Henryk Dudek, David Bumcrot, Frank Y Wang, Simon Jones, Janine Shulok, Lee L Rubin, Jeffery A Porter Journal of Biology 2002, 1:10 (6 November 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Characterization of small-molecule agonists and antagonists of the Hedgehog signaling pathway reveals that these candidate therapeutics act at the level of the pathway activator Smoothened, which may normally be regulated by an endogenous small molecule.

10.

36984
Accesses

Research article   Open Access Highly Accessed

Evidence for large domains of similarly expressed genes in the Drosophila genome

Paul T Spellman, Gerald M Rubin Journal of Biology 2002, 1:5 (18 June 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

11.

34980
Accesses

Research article   Open Access Highly Accessed

Adaptive evolution of centromere proteins in plants and animals

Paul B Talbert, Terri D Bryson, Steven Henikoff Journal of Biology 2004, 3:18 (31 August 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Centromere-binding proteins, like the DNA they bind, are rapidly evolving, a remarkable finding given that they are essential for every cell division and so would be expected to be very highly conserved.

12.

33376
Accesses

Research article   Open Access Highly Accessed

CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo

Joerg Dietrich, Ruolan Han, Yin Yang, Margot Mayer-Pröschel, Mark Noble Journal of Biology 2006, 5:22 (30 November 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Chemotherapeutic agents are more toxic to cells of the central nervous system than to cancer cells when administered to mice and cultured cells, providing an explanation for adverse neurological effects of systemic chemotherapy.

13.

33069
Accesses

Research article   Open Access Highly Accessed

Identification of conserved regulatory elements by comparative genome analysis

Boris Lenhard, Albin Sandelin, Luis Mendoza, Pär Engström, Niclas Jareborg, Wyeth W Wasserman Journal of Biology 2003, 2:13 (22 May 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

14.

31991
Accesses

Research article   Open Access Highly Accessed

Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae

Teresa Reguly, Ashton Breitkreutz, Lorrie Boucher, Bobby-Joe Breitkreutz, Gary C Hon, Chad L Myers, Ainslie Parsons, Helena Friesen, Rose Oughtred, Amy Tong, Chris Stark, Yuen Ho, David Botstein, Brenda Andrews, Charles Boone, Olga G Troyanskya, Trey Ideker, Kara Dolinski, Nizar N Batada, Mike Tyers Journal of Biology 2006, 5:11 (8 June 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A new literature-based yeast database documents over 33,000 biological interactions, manually curated from the primary literature, and provides an invaluable resource to benchmark high-throughput methods in the study of complex networks.

15.

31143
Accesses

Research article   Open Access Highly Accessed

The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal

Jens Böse, Achim D Gruber, Laura Helming, Stefanie Schiebe, Ivonne Wegener, Martin Hafner, Marianne Beales, Frank Köntgen, Andreas Lengeling Journal of Biology 2004, 3:15 (23 August 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

The phosphatidylserine receptor is not needed for the recognition of dying cells as previously thought, and instead plays a role in the differentiation of a wide range of tissues during embryogenesis.

16.

30996
Accesses

Research article   Open Access Highly Accessed

High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry

Claude Lechene, Francois Hillion, Greg McMahon, Douglas Benson, Alan M Kleinfeld, J Patrick Kampf, Daniel Distel, Yvette Luyten, Joseph Bonventre, Dirk Hentschel, Kwon Park, Susumu Ito, Martin Schwartz, Gilles Benichou, Georges Slodzian Journal of Biology 2006, 5:20 (5 October 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

For the first time it is possible to image and quantify at nanometer resolution biological samples labeled with stable isotopes, using multi-isotope imaging mass spectrometry, applicable to all fields of biomedical research.

17.

30980
Accesses

Research article   Open Access Highly Accessed

Differences in the way a mammalian cell and yeast cells coordinate cell growth and cell-cycle progression

Ian Conlon, Martin Raff Journal of Biology 2003, 2:7 (24 April 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 4 comments | F1000 Biology

18.

30460
Accesses

Research article   Open Access Highly Accessed

Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system

Ruolan Han, Yin M Yang, Joerg Dietrich, Anne Luebke, Margot Mayer-Pröschel, Mark Noble Journal of Biology 2008, 7:12 (22 April 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

The chemotherapy drug, 5-fluorouracil, causes delayed degeneration in the central nervous system of animals, a newly identified type of damage that helps explain the cognitive defects or `chemobrain` symptoms associated with cancer treatment.

19.

29988
Accesses

Research article   Open Access Highly Accessed

Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade

Simon A Hawley, Jérôme Boudeau, Jennifer L Reid, Kirsty J Mustard, Lina Udd, Tomi P Mäkelä, Dario R Alessi, D Grahame Hardie Journal of Biology 2003, 2:28 (24 September 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

20.

28395
Accesses

Minireview   Free Highly Accessed

Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements

Zhaolei Zhang, Mark Gerstein Journal of Biology 2003, 2:11 (6 June 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

21.

27885
Accesses

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Combined optical trapping and single-molecule fluorescence

Matthew J Lang, Polly M Fordyce, Steven M Block Journal of Biology 2003, 2:6 (24 February 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

22.

27602
Accesses

Research article   Open Access Highly Accessed

Astrocytes derived from glial-restricted precursors promote spinal cord repair

Jeannette E Davies, Carol Huang, Christoph Proschel, Mark Noble, Margot Mayer-Proschel, Stephen JA Davies Journal of Biology 2006, 5:7 (27 April 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Significantly better spinal cord repair in rats results from transplanting specific pre-differentiated cells, cultured to become immature neural-support cells, than from transplanting undifferentiated embryonic stem cells.

23.

27534
Accesses

Research article   Open Access Highly Accessed

Systematic identification of regulatory proteins critical for T-cell activation

Peter Chu, Jorge Pardo, Haoran Zhao, Connie C Li, Erlina Pali, Mary M Shen, Kunbin Qu, Simon X Yu, Betty CB Huang, Peiwen Yu, Esteban S Masuda, Susan M Molineaux, Frank Kolbinger, Gregorio Aversa, Jan de Vries, Donald G Payan, X Charlene Liao Journal of Biology 2003, 2:21 (15 September 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

27158
Accesses

Research article   Open Access Highly Accessed

Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm

Tadashi Okubo, Brigid LM Hogan Journal of Biology 2004, 3:11 (8 June 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Abnormal activation of the Wnt signaling pathway can alter the fate of progenitor cells that normally generate the lung, causing them to create gut cells instead.

25.

26541
Accesses

Research article   Open Access Highly Accessed

Environmental stresses can alleviate the average deleterious effect of mutations

Roy Kishony, Stanislas Leibler Journal of Biology 2003, 2:14 (29 May 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment | F1000 Biology

26.

26390
Accesses

Minireview   Free Highly Accessed

Gene expression neighborhoods

Brian Oliver, Michael Parisi, David Clark Journal of Biology 2002, 1:4 (1 July 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

27.

25589
Accesses

Minireview   Free Highly Accessed

Music, memory and emotion

Lutz Jäncke Journal of Biology 2008, 7:21 (8 August 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

28.

25006
Accesses

Research article   Open Access Highly Accessed

ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially

Chiara Vantaggiato, Ivan Formentini, Attilio Bondanza, Chiara Bonini, Luigi Naldini, Riccardo Brambilla Journal of Biology 2006, 5:14 (28 June 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The mitogen-activated protein kinases ERK1 and ERK2 have unexpectedly independent roles in normal and malignant Ras-dependent cell proliferation; ERK2 controls normal cell proliferation whereas ERK1 antagonizes ERK2 activity.

29.

23526
Accesses

Research article   Open Access Highly Accessed

Nuclear localization is required for Dishevelled function in Wnt/β-catenin signaling

Keiji Itoh, Barbara K Brott, Gyu-Un Bae, Marianne J Ratcliffe, Sergei Y Sokol Journal of Biology 2005, 4:3 (15 February 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Dishevelled, a key player in the Wnt/beta-catenin signalling pathway, doesn't only function in the cytoplasm and at the cell membrane, but must be imported into the nucleus to perform at least one key aspect of its function.

30.

21065
Accesses

Opinion   Free Highly Accessed

Top dogs: wolf domestication and wealth

Carlos A Driscoll, David W Macdonald Journal of Biology 2010, 9:10 (24 February 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Commenting on a phylogeographic analysis in BMC Biology that supports a Middle Eastern origin of small dogs, Driscoll and Macdonald speculate on the implications of wolf domestication and size reduction occurring at a time of transition between hunter-gatherer and sedentary societies.

31.

21023
Accesses

Research article   Open Access Highly Accessed

Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress

Markus Ralser, Mirjam M Wamelink, Axel Kowald, Birgit Gerisch, Gino Heeren, Eduard A Struys, Edda Klipp, Cornelis Jakobs, Michael Breitenbach, Hans Lehrach, Sylvia Krobitsch Journal of Biology 2007, 6:10 (21 December 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Yeast and C. elegans share a conserved cellular mechanism that counteracts the fatal consequences of oxidative stress by enabling the redirection of metabolic flux from glycolysis to the pentose phosphate pathway.

32.

20708
Accesses

Research article   Open Access Highly Accessed

Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network

Lan V Zhang, Oliver D King, Sharyl L Wong, Debra S Goldberg, Amy HY Tong, Guillaume Lesage, Brenda Andrews, Howard Bussey, Charles Boone, Frederick P Roth Journal of Biology 2005, 4:6 (1 June 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

The multiple complex biological interactions in a yeast cell can be mapped in a simple graphical form, enhancing our understanding of the networks of interaction by which components of a cell influence one another.

33.

20304
Accesses

Research article   Open Access Highly Accessed

Dosage compensation is less effective in birds than in mammals

Yuichiro Itoh, Esther Melamed, Xia Yang, Kathy Kampf, Susanna Wang, Nadir Yehya, Atila Van Nas, Kirstin Replogle, Mark R Band, David F Clayton, Eric E Schadt, Aldons J Lusis, Arthur P Arnold Journal of Biology 2007, 6:2 (22 March 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Male:female ratios of gene expression in zebra finch and chicken reveal that birds, unlike mammals, have surprisingly ineffective sex-chromosome dosage compensation mechanisms resulting in an imbalance between autosomal and sex-linked genes.

34.

19705
Accesses

Research article   Open Access Highly Accessed

Conservation of core gene expression in vertebrate tissues

Esther T Chan, Gerald T Quon, Gordon Chua, Tomas Babak, Miles Trochesset, Ralph A Zirngibl, Jane Aubin, Michael JH Ratcliffe, Andrew Wilde, Michael Brudno, Quaid D Morris, Timothy R Hughes Journal of Biology 2009, 8:33 (16 April 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

High conservation of tissue-specific expression is found across vertebrates yet there is a lack of conservation in common regulatory sequences/signatures.

35.

19629
Accesses

Opinion   Free Highly Accessed

The 'stem cell' concept: is it holding us back?

Arthur D Lander Journal of Biology 2009, 8:70 (21 September 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 2 comments |  Editor’s summary

Arthur Lander argues that the molecular definition of a stem cell is a mirage and 'stemness' is an emergent property of cells in their physiological context, so that the current concept is arguably an obstacle to research.

36.

19442
Accesses

Research news   Free

Transcriptional territories in the genome

Jonathan B Weitzman Journal of Biology 2002, 1:2 (25 June 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

37.

19423
Accesses

Research article   Open Access Highly Accessed

Global analysis of X-chromosome dosage compensation

Vaijayanti Gupta, Michael Parisi, David Sturgill, Rachel Nuttall, Michael Doctolero, Olga K Dudko, James D Malley, P Scott Eastman, Brian Oliver Journal of Biology 2006, 5:3 (16 February 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

In Drosophila germ cells, X chromosome genes are upregulated to balance their expression with that of autosomes; the same happens in somatic cells of mice and nematodes.

38.

18292
Accesses

Editorial   Open Access Highly Accessed

What are journals for?

Miranda Robertson Journal of Biology 2009, 8:1 (27 January 2009)

Full text | PDF |  Editor’s summary

Journal of Biology launches a re-review opt-out experiment in response to widespread dissatisfaction with peer review, and publishes the first of two new regular features - a full review on the ribosome and a question-and-answer feature on systems biology.

39.

18063
Accesses

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A global analysis of genetic interactions in Caenorhabditis elegans

Alexandra B Byrne, Matthew T Weirauch, Victoria Wong, Martina Koeva, Scott J Dixon, Joshua M Stuart, Peter J Roy Journal of Biology 2007, 6:8 (26 September 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A C. elegans genetic-interaction network built by combining gene mutants and knockdowns is the largest animal network to date, revealing redundancy among functional modules and surprisingly little conservation of network connections compared to yeast.

40.

17762
Accesses

Opinion   Free Highly Accessed

The nature of cell-cycle checkpoints: facts and fallacies

Alexey Khodjakov, Conly L Rieder Journal of Biology 2009, 8:88 (16 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

The development of the checkpoint concept was a landmark in the understanding of cell cycle control, but Alexey Khodjakov and Conly Rieder argue that it is widely misunderstood, to the detriment of progress in cell cycle research.

41.

17335
Accesses

Research article   Open Access Highly Accessed

Search for a 'Tree of Life' in the thicket of the phylogenetic forest

Pere Puigbò, Yuri I Wolf, Eugene V Koonin Journal of Biology 2009, 8:59 (13 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Koonin and colleagues, comparing a forest of 7000 phylogenetic trees, discern vertical inheritance even at the earliest stages of prokaryotic evolution, despite horizontal gene transfer, but the branching order of the earliest radiations may never be resolved.

42.

17247
Accesses

Opinion   Free Highly Accessed

Why didn't Darwin discover Mendel's laws?

Jonathan C Howard Journal of Biology 2009, 8:15 (24 February 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

In an opinion piece, Jonathan Howard suggests that Darwin failed to discover the laws of inheritance (Mendel’s laws) due to his focus on small quantitative variations as the raw material of evolution.

43.

16642
Accesses

Research news   Free Highly Accessed

Stress, sex and evolution

Pete Moore Journal of Biology 2003, 2:10 (27 June 2003)

Abstract | Full text | PDF | PubMed

44.

16531
Accesses

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Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production

Margaret Q Wang, Wankee Kim, Guangxia Gao, Ted A Torrey, Herbert C Morse, Pietro De Camilli, Stephen P Goff Journal of Biology 2003, 3:4 (4 December 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

45.

16476
Accesses

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Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function

Owain R Millington, Caterina Di Lorenzo, R Phillips, Paul Garside, James M Brewer Journal of Biology 2006, 5:5 (12 April 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Hemozoin pigment, released during malarial infection, is now known to cause dendritic cell failure and subsequent host immunosupression, explaining why people with malaria become prone to infection and respond poorly to vaccines.

46.

16184
Accesses

Research article   Open Access Highly Accessed

Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injury

Jeannette E Davies, Christoph Pröschel, Ningzhe Zhang, Mark Noble, Margot Mayer-Pröschel, Stephen JA Davies Journal of Biology 2008, 7:24 (19 September 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Glial cells can promote the repair of damaged spinal cord, but experiments in rats show that while some promote functional recovery others cause abnormal growth and pain, depending on the growth factor used to cultivate them in culture.

47.

16121
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Research article   Open Access Highly Accessed

The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans

Cheng-Wen Su, Suzanne Tharin, Yishi Jin, Bruce Wightman, Mona Spector, David Meili, Nancy Tsung, Christa Rhiner, Dimitris Bourikas, Esther Stoeckli, Gian Garriga, H Robert Horvitz, Michael O Hengartner Journal of Biology 2006, 5:9 (25 May 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Newly characterized in C. elegans, the protein UNC-69 interacts with kinesin–binding protein UNC-76 in a complex associated with trafficking vesicles along axons - a process that drives axon growth and helps synapse formation.

48.

15683
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The mathematics of sexual attraction

José A Feijó Journal of Biology 2010, 9:18 (29 March 2010)

Abstract | Full text | PDF | PubMed

49.

15519
Accesses

Minireview   Free

Controlling cell division in yeast and animals: does size matter?

Savraj S Grewal, Bruce A Edgar Journal of Biology 2003, 2:5 (24 April 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

50.

15095
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Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs

Andrey V Zavialov, Vasili V Hauryliuk, Måns Ehrenberg Journal of Biology 2005, 4:9 (27 June 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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