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51.
15147 Accesses
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Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs
Andrey V Zavialov, Vasili V Hauryliuk, Måns Ehrenberg Journal of Biology 2005, 4:9 (27 June 2005)
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52.
14937 Accesses
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A quantitative analysis of the mechanism that controls body size in Manduca sexta
HF Nijhout, G Davidowitz, DA Roff Journal of Biology 2006, 5:16 (2 August 2006)
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Editor’s summary
Final body size in the moth Manduca sexta can be predicted from the juvenile caterpillar by modeling three key growth measurements to reveal how growth rate, nutrition and temperature determine eventual body size.
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53.
14621 Accesses
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Q&A: What have we found out about the influenza A (H1N1) 2009 pandemic virus?
Stephen J Turner, Lorena E Brown, Peter C Doherty, Anne Kelso Journal of Biology 2009, 8:69 (18 September 2009)
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Editor’s summary
Stephen Turner and colleagues follow up their earlier Q&A on influenza A (H1N1) 2009 and ask what we now know about its transmissibility, pathogenicity and variability, and the likelihood of more severe disease in the Northern hemisphere winter.
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54.
14102 Accesses
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RNAi and the shape of things to come
Jonathan B Weitzman Journal of Biology 2003, 2:23 (4 November 2003)
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55.
13910 Accesses
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Electrical protein detection in cell lysates using high-density peptide-aptamer microarrays
David Evans, Steven Johnson, Sophie Laurenson, A Giles Davies, Paul Ko Ferrigno, Christoph Wälti Journal of Biology 2008, 7:3 (31 January 2008)
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Editor’s summary
Specific detection of protein isoforms in whole cell lysates is now more efficient with the arrival of a label-free electronic sensing system consisting of immobilized peptide aptamers on individual gold electrodes at the micron scale.
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56.
13527 Accesses
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Environmental stress and the effects of mutation
Santiago F Elena, J Arjan GM de Visser Journal of Biology 2003, 2:12 (26 June 2003)
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57.
13519 Accesses
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Parasite immunomodulation and polymorphisms of the immune system
Rick M Maizels Journal of Biology 2009, 8:62 (5 August 2009)
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Rick Maizels discusses a recent paper in BMC Biology on wild mammals that lend support to the hygiene hypothesis, and explains why genetic variants that reduce parasite-induced immunosuppression are associated with an increase in allergic reactions.
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58.
13359 Accesses
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Dishevelled and Wnt signaling: is the nucleus the final frontier?
Raymond Habas, Igor B Dawid Journal of Biology 2005, 4:2 (17 February 2005)
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59.
13355 Accesses
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Journal of Biology celebrates its fifth anniversary
Journal of Biology 2007, 6:5 (29 June 2007)
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60.
13342 Accesses
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Infectious causes of cancer and their detection
Lucy Dalton-Griffin, Paul Kellam Journal of Biology 2009, 8:67 (11 August 2009)
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Editor’s summary
Lucy Dalton-Griffin and Paul Kellam discuss the role of viruses in cancer following a recent paper in BMC Medical Genomics describing a new method of detecting viral DNA in cancer cells.
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61.
13249 Accesses
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Connecting LKB1 and AMPK links metabolism with cancer
Pete Moore Journal of Biology 2003, 2:24 (29 October 2003)
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62.
12408 Accesses
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A circuit supporting concentration-invariant odor perception in Drosophila
Kenta Asahina, Matthieu Louis, Silvia Piccinotti, Leslie B Vosshall Journal of Biology 2009, 8:9 (26 January 2009)
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| F1000 Biology
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Editor’s summary
In Drosophila, inhibitory interneurons are progressively recruited as olfactory sensory neurons are activated at increasing odor concentrations, allowing the flies to identify distinct odors at different intensities.
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63.
12142 Accesses
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The origin and evolution of lactation
Anthony V Capuco, R Michael Akers Journal of Biology 2009, 8:37 (24 April 2009)
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Capuco and Akers review the biology of lactation and discuss a new report in Genome Biology that compares the bovine genome with six other mammalian genomes to study how lactation and its regulation evolved.
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64.
12113 Accesses
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Timing the first human migration into eastern Asia
Roscoe Stanyon, Marco Sazzini, Donata Luiselli Journal of Biology 2009, 8:18 (6 February 2009)
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11977 Accesses
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Q&A: Epistasis
Frederick P Roth, Howard D Lipshitz, Brenda J Andrews Journal of Biology 2009, 8:35 (22 May 2009)
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Editor’s summary
The term epistasis has at least three meanings in biology. Brenda Andrews and colleagues explain in Q&A format how in its classical sense, epistasis allows biological pathways to be defined.
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66.
11851 Accesses
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Promoter architecture and the evolvability of gene expression
Itay Tirosh, Naama Barkai, Kevin J Verstrepen Journal of Biology 2009, 8:95 (14 December 2009)
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Editor’s summary
Major evolutionary change depends on changes in gene expression. Itay Tirosh and colleagues review recent research on the influence of promoter architecture and mutations in regulatory proteins on divergent expression patterns and suggest what is required for evolvability.
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67.
11564 Accesses
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Agonizing Hedgehog
Jonathan B Weitzman Journal of Biology 2002, 1:7 (6 November 2002)
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11510 Accesses
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The long term effects of chemotherapy on the central nervous system
Patricia K Duffner Journal of Biology 2006, 5:21 (30 November 2006)
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11427 Accesses
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How chemotherapy damages the central nervous system
Christina A Meyers Journal of Biology 2008, 7:11 (22 April 2008)
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11333 Accesses
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Endothelial adherens junctions and the actin cytoskeleton: an 'infinity net'?
Maria Grazia Lampugnani Journal of Biology 2010, 9:16 (8 April 2010)
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71.
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Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance
Basil Honegger, Milos Galic, Katja Köhler, Franz Wittwer, Walter Brogiolo, Ernst Hafen, Hugo Stocker Journal of Biology 2008, 7:10 (15 April 2008)
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Editor’s summary
The first functional insulin-binding protein identified in invertebrates, Imp-L2, controls Drosophila body size by regulating insulin-mediated growth and is essential for larval survival and dampening insulin signaling under starvation conditions.
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72.
11138 Accesses
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Small changes, big results: evolution of morphological discontinuity in mammals
Rodney L Honeycutt Journal of Biology 2008, 7:9 (18 March 2008)
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73.
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The therapeutic potential of modulators of the Hedgehog-Gli signaling pathway
Barbara Stecca, Ariel Altaba Journal of Biology 2002, 1:9 (6 November 2002)
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74.
11029 Accesses
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Intestine in the lung
Jonathan MW Slack Journal of Biology 2004, 3:10 (8 June 2004)
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75.
10837 Accesses
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Combined single-molecule force and fluorescence measurements for biology
Mark I Wallace, Justin E Molloy, David R Trentham Journal of Biology 2003, 2:4 (14 April 2003)
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