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	76. 1752 Accesses	Minireview The transcriptome of human monocyte subsets begins to emerge Fernando O Martinez Journal of Biology 2009, 8:99 (23 December 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Monocytes are circulating cells that can differentiate into macrophages with either repair and maintenance or inflammatory properties. Martinez discusses recent papers, including one published in BMC Genomics, that help define these distinct properties and thus identify therapeutic targets.
	77. 1752 Accesses	Minireview RNA interference in nematodes and the chance that favored Sydney Brenner Marie-Anne Félix Journal of Biology 2008, 7:34 (13 November 2008) Abstract \| Full text \| PDF \| PubMed
	78. 1745 Accesses	Minireview Forward genetics in Tribolium castaneum: opening new avenues of research in arthropod biology Andrew D Peel Journal of Biology 2009, 8:106 (30 December 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Peel discusses the merits of the flour beetle over the fruit fly as a new arthropod model organism and describes how a new mutagenesis screen published in BMC Biology increases the usefulness of this creature.
	79. 1739 Accesses	Research article The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal Jens Böse, Achim D Gruber, Laura Helming, Stefanie Schiebe, Ivonne Wegener, Martin Hafner, Marianne Beales, Frank Köntgen, Andreas Lengeling Journal of Biology 2004, 3:15 (23 August 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary The phosphatidylserine receptor is not needed for the recognition of dying cells as previously thought, and instead plays a role in the differentiation of a wide range of tissues during embryogenesis.
	80. 1739 Accesses	Minireview The THO complex as a key mRNP biogenesis factor in development and cell differentiation Sonia Jimeno, Andrés Aguilera Journal of Biology 2010, 9:6 (28 January 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The THO complex is implicated in RNA export from the nucleus, but exactly how is not clear. Jimeno and Aguilera discuss a new report on the THOC5 subunit in BMC Biology that suggests a role in differentiation.
	81. 1719 Accesses	Minireview Exploiting the promiscuity of imatinib Shun J Lee, Jean YJ Wang Journal of Biology 2009, 8:30 (15 April 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Lee and Wang discuss how the structural flexibility of the cancer drug imatinib (Gleevec) accounts for the drug's off-target promiscuity, illustrated by a structural study published in BMC Structural Biology.
	82. 1679 Accesses	Minireview Cryptic biodiversity in a changing world Luciano B Beheregaray, Adalgisa Caccone Journal of Biology 2007, 6:9 (21 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	83. 1658 Accesses	Research article Identification of conserved regulatory elements by comparative genome analysis Boris Lenhard, Albin Sandelin, Luis Mendoza, Pär Engström, Niclas Jareborg, Wyeth W Wasserman Journal of Biology 2003, 2:13 (22 May 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	84. 1654 Accesses	Research article Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm Tadashi Okubo, Brigid LM Hogan Journal of Biology 2004, 3:11 (8 June 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Abnormal activation of the Wnt signaling pathway can alter the fate of progenitor cells that normally generate the lung, causing them to create gut cells instead.
	85. 1630 Accesses	Minireview Vernalization in cereals Elizabeth S Dennis, W James Peacock Journal of Biology 2009, 8:57 (22 June 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Elizabeth Dennis and James Peacock review recent advances in the molecular basis of the vernalization response that, with the increase in day length at the end of the winter season, triggers flowering.
	86. 1604 Accesses	Research article Adaptive evolution of centromere proteins in plants and animals Paul B Talbert, Terri D Bryson, Steven Henikoff Journal of Biology 2004, 3:18 (31 August 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary Centromere-binding proteins, like the DNA they bind, are rapidly evolving, a remarkable finding given that they are essential for every cell division and so would be expected to be very highly conserved.
	87. 1591 Accesses	Research article Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function Owain R Millington, Caterina Di Lorenzo, R Phillips, Paul Garside, James M Brewer Journal of Biology 2006, 5:5 (12 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Hemozoin pigment, released during malarial infection, is now known to cause dendritic cell failure and subsequent host immunosupression, explaining why people with malaria become prone to infection and respond poorly to vaccines.
	88. 1567 Accesses	Research article Systematic identification of regulatory proteins critical for T-cell activation Peter Chu, Jorge Pardo, Haoran Zhao, Connie C Li, Erlina Pali, Mary M Shen, Kunbin Qu, Simon X Yu, Betty CB Huang, Peiwen Yu, Esteban S Masuda, Susan M Molineaux, Frank Kolbinger, Gregorio Aversa, Jan de Vries, Donald G Payan, X Charlene Liao Journal of Biology 2003, 2:21 (15 September 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	89. 1532 Accesses	Minireview Reprogramming of the non-coding transcriptome during brain development Saba Valadkhan, Timothy W Nilsen Journal of Biology 2010, 9:5 (5 February 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Valadkhan and Nilsen discuss the mystery of long noncoding RNAs and a recent global expression study in BMC Neuroscience that provides a platform for answering fundamental questions about their role in the development of the brain.
	90. 1532 Accesses	Minireview Adaptation by introgression Michael L Arnold, Noland H Martin Journal of Biology 2009, 8:82 (13 October 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	91. 1530 Accesses	Question & Answer Q&A: What can microfluidics do for stem-cell research? Marie Csete Journal of Biology 2010, 9:1 (11 February 2010) Full text \| PDF \| PubMed
	92. 1529 Accesses	Minireview X-chromosome inactivation: the molecular basis of silencing Barbara Panning Journal of Biology 2008, 7:30 (27 October 2008) Abstract \| Full text \| PDF \| PubMed
	93. 1525 Accesses	Minireview The future of artemisinins: natural, synthetic or recombinant? Marcel Hommel Journal of Biology 2008, 7:38 (15 December 2008) Abstract \| Full text \| PDF \| PubMed
	94. 1520 Accesses	Opinion Beyond toxicity: aryl hydrocarbon receptor-mediated functions in the immune system Brigitta Stockinger Journal of Biology 2009, 8:61 (17 August 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Brigitta Stockinger argues that the immunosuppressive effects of dioxin and other toxic aryl hydrocarbons may reflect disruption of the regulatory interactions between immune cells, which variably express the specific receptor for these compounds.
	95. 1518 Accesses	Minireview Malaria pigment paralyzes dendritic cells Britta C Urban, Stephen Todryk Journal of Biology 2006, 5:4 (12 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	96. 1515 Accesses	Minireview Dishevelled and Wnt signaling: is the nucleus the final frontier? Raymond Habas, Igor B Dawid Journal of Biology 2005, 4:2 (17 February 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	97. 1496 Accesses	Research article Nuclear localization is required for Dishevelled function in Wnt/β-catenin signaling Keiji Itoh, Barbara K Brott, Gyu-Un Bae, Marianne J Ratcliffe, Sergei Y Sokol Journal of Biology 2005, 4:3 (15 February 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary Dishevelled, a key player in the Wnt/beta-catenin signalling pathway, doesn't only function in the cytoplasm and at the cell membrane, but must be imported into the nucleus to perform at least one key aspect of its function.
	98. 1485 Accesses	Review The ribosome returned Peter B Moore Journal of Biology 2009, 8:8 (26 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	99. 1484 Accesses	Minireview Limb regeneration revisited Jessica L Whited, Clifford J Tabin Journal of Biology 2009, 8:5 (13 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	100. 1480 Accesses	Minireview Observing bacteria through the lens of social evolution Carey D Nadell, Bonnie L Bassler, Simon A Levin Journal of Biology 2008, 7:27 (30 September 2008) Abstract \| Full text \| PDF \| PubMed