Journal of Biology | Most Viewed

Advertisement

Articles

Display/download options Articles per page: 25 | 50 | 100

Display options

Editor's summary Citation

Download options

Send
To

	All
	76. 171 Accesses	Opinion The nature of cell-cycle checkpoints: facts and fallacies Alexey Khodjakov, Conly L Rieder Journal of Biology 2009, 8:88 (16 November 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary The development of the checkpoint concept was a landmark in the understanding of cell cycle control, but Alexey Khodjakov and Conly Rieder argue that it is widely misunderstood, to the detriment of progress in cell cycle research.
	77. 168 Accesses	Minireview Regeneration review reprise Jessica L Whited, Clifford J Tabin Journal of Biology 2010, 9:15 (16 February 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Stem cell biology and new high throughput techniques are inspiring new advances in research on regeneration. Whited and Tabin discuss recent developments, including two recent reports in BMC Biology that may mean a reevaluation of the regenerative prospects for humans.
	78. 166 Accesses	Minireview An expanded evolutionary role for flower symmetry genes Lena C Hileman, Pilar Cubas Journal of Biology 2009, 8:90 (6 November 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Cubas and Hileman discuss studies, including one in BMC Evolutionary Biology, showing that the CYC-like genes that control floral symmetry have profound effects on other features and have been recruited to diverse roles in floral evolution.
	79. 164 Accesses	Minireview The long term effects of chemotherapy on the central nervous system Patricia K Duffner Journal of Biology 2006, 5:21 (30 November 2006) Abstract \| Full text \| PDF \| PubMed
	80. 163 Accesses	Question & Answer Q&A: Cooperativity James E Ferrell Journal of Biology 2009, 8:53 (16 June 2009) Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary James Ferrell explains in Q&A format how cooperativity can tune the behaviour of biological macromolecules to their physiological functions, and can be achieved in many different ways.
	81. 164 Accesses	Opinion The 'stem cell' concept: is it holding us back? Arthur D Lander Journal of Biology 2009, 8:70 (21 September 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments \| Editor’s summary Arthur Lander argues that the molecular definition of a stem cell is a mirage and 'stemness' is an emergent property of cells in their physiological context, so that the current concept is arguably an obstacle to research.
	82. 163 Accesses	Minireview RNA interference in nematodes and the chance that favored Sydney Brenner Marie-Anne Félix Journal of Biology 2008, 7:34 (13 November 2008) Abstract \| Full text \| PDF \| PubMed
	83. 161 Accesses	Minireview Infectious causes of cancer and their detection Lucy Dalton-Griffin, Paul Kellam Journal of Biology 2009, 8:67 (11 August 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Lucy Dalton-Griffin and Paul Kellam discuss the role of viruses in cancer following a recent paper in BMC Medical Genomics describing a new method of detecting viral DNA in cancer cells.
	84. 158 Accesses	Minireview The human spermatozoon – a stripped down but refined machine Christopher LR Barratt, Vanessa Kay, Senga K Oxenham Journal of Biology 2009, 8:63 (7 August 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Christopher Barratt and colleagues review our current knowledge of the human sperm cell and available treatments for male subfertility in the light of a recent paper in BMC Developmental Biology on the role of the annulus.
	85. 158 Accesses	Minireview Evolution of virulence in malaria Bridget Penman, Sunetra Gupta Journal of Biology 2008, 7:22 (28 August 2008) Abstract \| Full text \| PDF \| PubMed
	86. 159 Accesses	Research article Environmental stresses can alleviate the average deleterious effect of mutations Roy Kishony, Stanislas Leibler Journal of Biology 2003, 2:14 (29 May 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| F1000 Biology
	87. 158 Accesses	Review The ribosome returned Peter B Moore Journal of Biology 2009, 8:8 (26 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	88. 156 Accesses	Research article Combined optical trapping and single-molecule fluorescence Matthew J Lang, Polly M Fordyce, Steven M Block Journal of Biology 2003, 2:6 (24 February 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	89. 156 Accesses	Research article Global analysis of X-chromosome dosage compensation Vaijayanti Gupta, Michael Parisi, David Sturgill, Rachel Nuttall, Michael Doctolero, Olga K Dudko, James D Malley, P Scott Eastman, Brian Oliver Journal of Biology 2006, 5:3 (16 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary In Drosophila germ cells, X chromosome genes are upregulated to balance their expression with that of autosomes; the same happens in somatic cells of mice and nematodes.
	90. 154 Accesses	Research article Nuclear localization is required for Dishevelled function in Wnt/β-catenin signaling Keiji Itoh, Barbara K Brott, Gyu-Un Bae, Marianne J Ratcliffe, Sergei Y Sokol Journal of Biology 2005, 4:3 (15 February 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary Dishevelled, a key player in the Wnt/beta-catenin signalling pathway, doesn't only function in the cytoplasm and at the cell membrane, but must be imported into the nucleus to perform at least one key aspect of its function.
	91. 152 Accesses	Research article Adaptive evolution of centromere proteins in plants and animals Paul B Talbert, Terri D Bryson, Steven Henikoff Journal of Biology 2004, 3:18 (31 August 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary Centromere-binding proteins, like the DNA they bind, are rapidly evolving, a remarkable finding given that they are essential for every cell division and so would be expected to be very highly conserved.
	92. 152 Accesses	Minireview Comparative embryology without a microscope: using genomic approaches to understand the evolution of development David A Garfield, Gregory A Wray Journal of Biology 2009, 8:65 (21 July 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The early stages of development are generally very highly conserved. Garfield and Wray discuss recent genome-scale studies published in BMC Biology and aimed at testing three theories of how selection acts on early embryos.
	93. 152 Accesses	Minireview The THO complex as a key mRNP biogenesis factor in development and cell differentiation Sonia Jimeno, Andrés Aguilera Journal of Biology 2010, 9:6 (28 January 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The THO complex is implicated in RNA export from the nucleus, but exactly how is not clear. Jimeno and Aguilera discuss a new report on the THOC5 subunit in BMC Biology that suggests a role in differentiation.
	94. 152 Accesses	Minireview Movement in ribosome translocation Christopher S Fraser, John WB Hershey Journal of Biology 2005, 4:8 (27 June 2005) Abstract \| Full text \| PDF \| PubMed
	95. 153 Accesses	Minireview Aquaglyceroporins: ancient channels for metalloids Hiranmoy Bhattacharjee, Rita Mukhopadhyay, Saravanamuthu Thiyagarajan, Barry P Rosen Journal of Biology 2008, 7:33 (7 November 2008) Abstract \| Full text \| PDF \| PubMed
	96. 150 Accesses	Research article Identification of conserved regulatory elements by comparative genome analysis Boris Lenhard, Albin Sandelin, Luis Mendoza, Pär Engström, Niclas Jareborg, Wyeth W Wasserman Journal of Biology 2003, 2:13 (22 May 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	97. 149 Accesses	Research article Systematic identification of regulatory proteins critical for T-cell activation Peter Chu, Jorge Pardo, Haoran Zhao, Connie C Li, Erlina Pali, Mary M Shen, Kunbin Qu, Simon X Yu, Betty CB Huang, Peiwen Yu, Esteban S Masuda, Susan M Molineaux, Frank Kolbinger, Gregorio Aversa, Jan de Vries, Donald G Payan, X Charlene Liao Journal of Biology 2003, 2:21 (15 September 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	98. 147 Accesses	Question & Answer Q&A: What can microfluidics do for stem-cell research? Marie Csete Journal of Biology 2010, 9:1 (11 February 2010) Full text \| PDF \| PubMed
	99. 146 Accesses	Minireview Reconstructing prokaryotic transcriptional regulatory networks: lessons from actinobacteria Thiago M Venancio, L Aravind Journal of Biology 2009, 8:29 (15 April 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Venancio and Aravind review recent studies, including one in BMC Systems Biology, that offer new ways to reconstruct transcriptional regulatory networks in previously uncharacterised prokaryotes, such as the actinobacteria.
	100. 146 Accesses	Minireview The genetics of gender and life span John Tower, Michelle Arbeitman Journal of Biology 2009, 8:38 (29 April 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Tower and Arbeitman discuss two studies in BMC Evolutionary Biology showing that the genetic differences between male and female seed beetles and in fruit flies have a significant effect upon aging and life span.