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1: J Biol. 2003;2(2):11. Epub 2003 Jun 6.
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Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements.

Zhang Z, Gerstein M.

Department of Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, CT 06520-8114, USA.

Phylogenetic footprinting is an approach to finding functionally important sequences in the genome that relies on detecting their high degrees of conservation across different species. A new study shows how much it improves the prediction of gene-regulatory elements in the human genome.

Publication Types:
PMID: 12814519 [PubMed - indexed for MEDLINE]

PMCID: PMC193683