Related Articles for PubMed (Select 14511394)

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.

Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Mäkelä TP, Alessi DR, Hardie DG.

J Biol. 2003;2(4):28. Epub 2003 Sep 24.

PMID: 14511394 [PubMed - indexed for MEDLINE]

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Effects of 3-phosphoglycerate and other metabolites on the activation of AMP-activated protein kinase by LKB1-STRAD-MO25.

Ellingson WJ, Chesser DG, Winder WW.

Am J Physiol Endocrinol Metab. 2007 Feb;292(2):E400-7. Epub 2006 Sep 19.

PMID: 16985256 [PubMed - indexed for MEDLINE]

Long-chain acyl-CoA esters inhibit phosphorylation of AMP-activated protein kinase at threonine-172 by LKB1/STRAD/MO25.

Taylor EB, Ellingson WJ, Lamb JD, Chesser DG, Winder WW.

Am J Physiol Endocrinol Metab. 2005 Jun;288(6):E1055-61. Epub 2005 Jan 11.

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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

Lizcano JM, Göransson O, Toth R, Deak M, Morrice NA, Boudeau J, Hawley SA, Udd L, Mäkelä TP, Hardie DG, Alessi DR.

EMBO J. 2004 Feb 25;23(4):833-43. Epub 2004 Feb 19.

PMID: 14976552 [PubMed - indexed for MEDLINE]

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Analysis of the LKB1-STRAD-MO25 complex.

Boudeau J, Scott JW, Resta N, Deak M, Kieloch A, Komander D, Hardie DG, Prescott AR, van Aalten DM, Alessi DR.

J Cell Sci. 2004 Dec 15;117(Pt 26):6365-75. Epub 2004 Nov 23.

PMID: 15561763 [PubMed - indexed for MEDLINE]

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.

Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA, Cantley LC.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3329-35. Epub 2004 Feb 25.

PMID: 14985505 [PubMed - indexed for MEDLINE]

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The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation.

Jaleel M, Villa F, Deak M, Toth R, Prescott AR, Van Aalten DM, Alessi DR.

Biochem J. 2006 Mar 15;394(Pt 3):545-55.

PMID: 16396636 [PubMed - indexed for MEDLINE]

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Characterization of the AMP-activated protein kinase pathway in chickens.

Proszkowiec-Weglarz M, Richards MP, Ramachandran R, McMurtry JP.

Comp Biochem Physiol B Biochem Mol Biol. 2006 Jan;143(1):92-106. Epub 2005 Dec 15.

PMID: 16343965 [PubMed - indexed for MEDLINE]

Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate.

Jaleel M, McBride A, Lizcano JM, Deak M, Toth R, Morrice NA, Alessi DR.

FEBS Lett. 2005 Feb 28;579(6):1417-23.

PMID: 15733851 [PubMed - indexed for MEDLINE]

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Evidence against regulation of AMP-activated protein kinase and LKB1/STRAD/MO25 activity by creatine phosphate.

Taylor EB, Ellingson WJ, Lamb JD, Chesser DG, Compton CL, Winder WW.

Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E661-9. Epub 2005 Nov 8.

PMID: 16278246 [PubMed - indexed for MEDLINE]

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Thyroid hormone effects on LKB1, MO25, phospho-AMPK, phospho-CREB, and PGC-1alpha in rat muscle.

Branvold DJ, Allred DR, Beckstead DJ, Kim HJ, Fillmore N, Condon BM, Brown JD, Sudweeks SN, Thomson DM, Winder WW.

J Appl Physiol. 2008 Oct;105(4):1218-27. Epub 2008 Jul 31.

PMID: 18669938 [PubMed - indexed for MEDLINE]

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IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner.

Suzuki A, Kusakai G, Kishimoto A, Shimojo Y, Ogura T, Lavin MF, Esumi H.

Biochem Biophys Res Commun. 2004 Nov 19;324(3):986-92.

PMID: 15485651 [PubMed - indexed for MEDLINE]

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Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR.

Sakamoto K, Göransson O, Hardie DG, Alessi DR.

Am J Physiol Endocrinol Metab. 2004 Aug;287(2):E310-7. Epub 2004 Apr 6.

PMID: 15068958 [PubMed - indexed for MEDLINE]

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Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells.

Xie Z, Dong Y, Zhang M, Cui MZ, Cohen RA, Riek U, Neumann D, Schlattner U, Zou MH.

J Biol Chem. 2006 Mar 10;281(10):6366-75. Epub 2006 Jan 9.

PMID: 16407220 [PubMed - indexed for MEDLINE]

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LKB1 is the upstream kinase in the AMP-activated protein kinase cascade.

Woods A, Johnstone SR, Dickerson K, Leiper FC, Fryer LG, Neumann D, Schlattner U, Wallimann T, Carlson M, Carling D.

Curr Biol. 2003 Nov 11;13(22):2004-8.

PMID: 14614828 [PubMed - indexed for MEDLINE]

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MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm.

Boudeau J, Baas AF, Deak M, Morrice NA, Kieloch A, Schutkowski M, Prescott AR, Clevers HC, Alessi DR.

EMBO J. 2003 Oct 1;22(19):5102-14.

PMID: 14517248 [PubMed - indexed for MEDLINE]

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Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD.

Baas AF, Boudeau J, Sapkota GP, Smit L, Medema R, Morrice NA, Alessi DR, Clevers HC.

EMBO J. 2003 Jun 16;22(12):3062-72.

PMID: 12805220 [PubMed - indexed for MEDLINE]

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LKB1-dependent signaling pathways.

Alessi DR, Sakamoto K, Bayascas JR.

Annu Rev Biochem. 2006;75:137-63. Review.

PMID: 16756488 [PubMed - indexed for MEDLINE]

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AICAR induces phosphorylation of AMPK in an ATM-dependent, LKB1-independent manner.

Sun Y, Connors KE, Yang DQ.

Mol Cell Biochem. 2007 Dec;306(1-2):239-45. Epub 2007 Sep 5.

PMID: 17786544 [PubMed - indexed for MEDLINE]

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Endurance training increases LKB1 and MO25 protein but not AMP-activated protein kinase kinase activity in skeletal muscle.

Taylor EB, Hurst D, Greenwood LJ, Lamb JD, Cline TD, Sudweeks SN, Winder WW.

Am J Physiol Endocrinol Metab. 2004 Dec;287(6):E1082-9. Epub 2004 Aug 3.

PMID: 15292028 [PubMed - indexed for MEDLINE]

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