http://jbiol.com/content/3/4/13/comments The latest comments on the article 'The curious world of apoptotic cell clearance' 2004-10-15T00:00:00Z This is an RSS newsfeed from BioMed Central It is intended to be used with an RSS reader. For more information about RSS newsfeeds from BioMed Central, visit http://www.biomedcentral.com/info/about/rss/ http://jbiol.com/content/3/4/13/comments#78454 <p>A paper was published in Development online (Development. 2004 Oct 6 [Epub ahead of print]), reporting that the PSR knockdown by a PSR morpholino oligonucleotide led to accumulation of a large number of dead apoptotic cells in whole early embryo. These unengulfed cells interfere with embryonic cell migration. In addition, normal development of the somite, brain, heart, and notochord was sequentially disrupted up to 24 hours post-fertilization. The phenotypes of the PSR knockdown in Zebrafish are quite similar to the PSR knockout phenotypes reported by Li et al. in Science. Thus in three organisms examined so far (worm, zebrafish, and mice) PSR is important for removal of apoptotic cell corpses. I think that this paper will help resolve the current controversial regarding PSR.</p> Ding Xue 2004-10-15T00:00:00Z